γδ T cells increase with Mycobacterium avium complex infection but not with tuberculosis in AIDS patients

International Immunology

Volumn 11, Issue 9, 1999, Pages 1475-1478

  Pellegrin, J L ^a   Taupin, J L ^a   Dupon, M ^a   Ragnaud, J M ^a   Maugein, J ^b   Bonneville, M ^c   Moreau, J F ^a  

^a Hopitaux Universitaires de Bordeaux   (France)

^b BORDEAUX UNIVERSITY HOSPITAL   (France)

^c INSERM   (France)

Author keywords

TCR; AIDS; Immunosuppression; Mycobacterial infections; Opportunistic infections; T lymphocytes; Tuberculosis

Indexed keywords

T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; CD3 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BACTERIAL IMMUNITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MYCOBACTERIOSIS; MYCOBACTERIUM INTRACELLULARE AVIUM; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS; AIDS RELATED COMPLEX; ATYPICAL MYCOBACTERIOSIS; CD4 LYMPHOCYTE COUNT; CELLULAR IMMUNITY; COHORT ANALYSIS; COMPARATIVE STUDY; FOLLOW UP; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE DEFICIENCY; IMMUNOLOGY; MICROBIOLOGY; MYCOBACTERIUM TUBERCULOSIS; T LYMPHOCYTE SUBPOPULATION;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIGENS, CD3; ANTIGENS, CD45; ANTIGENS, CD8; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; FOLLOW-UP STUDIES; HIV SEROPOSITIVITY; HIV-1; HUMANS; IMMUNITY, CELLULAR; IMMUNOCOMPROMISED HOST; LYMPHOCYTE COUNT; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS;

EID: 0032589148     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.9.1475     Document Type: Article

References (14)

1. Haas, W., Pereira, P. and Tonegawa, S. 1993. Gamma/delta cells. Annu. Rev. Immunol. 11:637.
2. Kronenberg, M. 1994. Antigens recognized by γδ T cells. Curr. Opin. Immunol. 6:64.
3. Kasper, L. H., Matsuura, T., Fonseka, S., Arruda, J., Channon, J. Y. and Khan, I. A. 1996. Induction of γδ T cells during acute murine infection with Toxoplasma gondii. J. Immunol. 157:5521.
4. Constant, P., Davodeau, F., Peyrat, M. A., Poquet, Y., Puzo, G., Bonneville, M. and Fournié, J. J. 1994. Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands. Science 264:267.
5. δ2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands. J. Immunol. 154:5986.
6. + T cell expansion in the peripheral blood of HIV-infected persons. J. Immunol. 154:1418.
7. - T lymphocytes in AIDS patients with disseminated Mycobacterium avium-intracellular complex infection. J. Infect. Dis. 174:969.
8. Chêne, G., Dabis, F., Salamon, R. and GECSA. 1992. Hospital-based surveillance of HIV infection: epidemiological trends, Bordeaux, France, 1983-1989. Eur. J. Epidemiol. 8:58.
9. + subset. J. Infect. Dis. 174:1309.
10. Pechhold, K., Wesch, D., Schondelmaier, S. and Kabelitz, D. 1994. Primary activation of V gamma 9-expressing gamma delta T cells by Mycobacterium tuberculosis. Requirement for Th-1 type CD4 T cell help and inhibition by IL-10. J. Immunol. 152:4984.
11. Wesch, D., Kabelitz, D., Friese, K. and Pechhold, K. 1996. Mycobacteria-reactive gamma delta T cells in HIV-infected individuals: lack of V gamma 9 cell responsiveness is due to deficiency of antigen-specific CD4 T helper type 1 cells. Eur. J. Immunol. 26:557.
12. Constant, P., Poquet, Y., Peyrat, M. A., Davodeau, F., Bonneville, M. and Fournié, J. J. 1995. The antituberculous Mycobacterium bovis BCG vaccine is an attenuated mycobacterial producer of phosphorylated nonpeptidic antigens for human gamma delta T cells. Infect. Immun. 63:4628.
13. Li, B. Q., Rossman, M. D., Imir, T., Onereyuboglu, A. F., Lee, C. W., Biancanello, R. and Carding, S. R. 1996. Disease-specific changes in gamma delta T cell repertoire and function in patients with pulmonary tuberculosis. J. Immunol. 157:4222.
14. Roberts, S. J., Smith, A. L., West, A. B., Wen, L., Findly, R. C., Owen, M. J. and Hayday, A. C. 1996. T cell alpha beta(+) deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium. Proc. Nat/Acad. Sci. USA 93:11774.