Immunolocalization of IL-1β and IL-6 in optic nerves of patients with AIDS

Current Eye Research

Volumn 19, Issue 3, 1999, Pages 264-268

  Saadati, Hossein G ^a   Khan, Iftikhar A ^a   Lin, Xiang Hong ^a   Kadakia, Anish ^a   Heller, Keith B ^a   Sadun, Alfredo A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

AIDS; Immunohistochemistry; Interleukin 1 ; Interleukin 6; Optic nerve

Indexed keywords

CYTOKINE; DIAMINOBENZIDINE; HORSERADISH PEROXIDASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 1;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL TYPE; CONTROLLED STUDY; DEMYELINATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MICROGLIA; NERVE CELL DEGENERATION; OPTIC NERVE; OPTIC NERVE DISEASE; PRIORITY JOURNAL; BIOSYNTHESIS; ENDOTHELIUM; METABOLISM;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ASTROCYTES; ENDOTHELIUM; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; INTERLEUKIN-6; MACROPHAGES; MICROGLIA; OPTIC NERVE; OPTIC NERVE DISEASES;

EID: 0032586270     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.19.3.264.5319     Document Type: Article

References (24)

1. Tyor WR, Glass JD, Griffin JW, Becker PS, McArthur JC, Bezman L, Griffin DE. Cytokine expression in the brain during the acquired immunodeficiency syndrome. Ann Neurol. 1992;31: 349-60.
2. Benveniste EN. Cytokine Circuits in Brain: Implications for AIDS Dementia Complex. HIV and the Brain. New York, USA: Raven Press Ltd; 1994: 71-87.
3. Merrill JE, Chen IS. HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease. FASEB. 1991;5:2391-7.
4. Madigan MC, Sadun AA, Rao NS, Dugel PU, Tenhula WN, Gill PS. Tumor necrosis factor (TNF-alpha)-induced optic neuropathy in rabbits. Neurol Res. 1996;18:176-184.
5. Arai K, Lee F, Miyajima A, Miyatake S, Arai N, Yokota T. Cytokines: coordinators of immune and inflammatory response. Annu Rev Biochem. 1990;59:783-836.
6. Gallo P, Frei K, Rordorf C, Lazdins J, Tavolato B, Fontana A. Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in the cerebrospinal fluid. J of NeuroImmun. 1989;23:109-116.
7. Swingler M, Easton A, Morris A. Cytokine augmentation of HIV-1 LTR-driven gene expression in neural cells. AIDS Res and Hum Retroviruses. 1992:8:487-493.
8. Torre D, Zeroli C, Ferraro G, Speranza F, Tambini R, Martegani R, Fiori GP. Cerebrospinal fluid levels of IL-6 in patients with acute infections of the central nervous system. Scand J of Infect Dis. 1992;24:787-91.
9. Lin XH, Kashima Y, Khan M, Heller KB, Gu XZ, Sadun AA. An immuno-histochemical study of TNF-α in optic nerves from AIDS patients. Curr Eye Res. 1997;16:1064-68.
10. Kolesnick RN, Golde DW. The sphingomyelin pathway in TNF and IL-1 signaling. Cell. 1994;77:325-328.
11. Heller, R. A. and Kronke, M. TNF receptor mediated signaling pathways. J Cell Biol. 1994;126:5-9.
12. Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. Microglial cell cytotoxicity for oligodendrocytes is mediated through nitric oxide. J Immunol. 1993;151: 2132-2141.
13. Merrill JE. Effects of interleukin-1 and tumor necrosis factor-alpha on astrocytes, microglia, oligodendrocytes, and glial precursors in vitro. Develop Neurosci. 1991; 13:130-137.
14. Robbins DS, Shirazi Y, Drysdale BE, Lieberman A, Shin HS, Shin ML. Production of cytotoxic factors for oligodendrocytes by stimulated astrocytes. J Immunol. 1987;139:2593-2597.
15. Vasilakos J, Sjivers B. Watch for ICE in neurodegeneration. Mol Psych. 1996;1:72-6.
16. Rothwell NJ, Strijbos PJ. Cytokines in neurodegeneration and repair. Int J of Develop Neurosci. 1995;13:179-185.
17. Bethea JR. Interleukin-1beta induction of tumor necrosis factor-alpha gene expression in human astroglioma cells. J of Neuroimmun. 1992;36:179-191.
18. Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell. 1993;75; 1169-1178.
19. Lipton SA. Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120. Neuro Report. 1992;3:913-915.
20. Fiebich BJ, Lieb K, Hull M, Berger M, Bauer J. Effects of NSAIDs on IL-1beta-induced IL-6 mRNA and protein synthesis in human astrocytoma cells. Neuro Report. 1996;7:1209-1213.
21. Carman-Krzan M, Wise G. Arachidonic acid lipoxygenation may mediate Interleukin-1 stimulation of nerve growth factor secretion in astroglial cultures. J of Neurosci Res. 1993;34:225-232.
22. Faber-Elman A, Solomon A, Abraham JA, Marikovsky M. Schwartz M. Involvement of wound-associated factors in rat brain astrocyte migratory response to axonal injury: In vitro stimulation. J of Clin Invest. 1996;97: 162-171.
23. Martiney JA, Litwak M, Berman JW, Arezzo JC, Brosnan CF. Pathophysiological effect of Interleukin-1 in the rabbit retina. Am J Path. 1990;137:1411-1423.
24. Burton BJ, Leff A, Plant GT. Steroid-responsive HIV optic neuropathy. J of Neuro-Ophth. 1998;18:25-29.