Watch for ICE in neurodegeneration

Molecular Psychiatry

Volumn 1, Issue 1, 1996, Pages 72-76

  Vasilakos, J ^a   Shivers, B ^a  

^a PFIZER INC   (United States)

Author keywords

Apoptosis; CED 3; Cysteine protease; ICE; Necrosis; Neurodegeneration

Indexed keywords

CYSTEINE PROTEINASE; INTERLEUKIN 1; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL; CELL DEATH; CYTOLOGY; ENZYMOLOGY; HUMAN; NERVE CELL; NERVE DEGENERATION; PHYSIOLOGY; REVIEW;

ANIMALS; CASPASE 1; CELL DEATH; CYSTEINE ENDOPEPTIDASES; HUMANS; INTERLEUKIN-1; NERVE DEGENERATION; NEURONS;

EID: 0030090883     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Kerr J, Wylie A, Currie A. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257.
2. Glücksmann A. Cell death in normal vertebrate ontogeny. Biol Rev 1951; 26: 59-86.
3. Oppenheim R. Naturally occurring cell death during neural development. Trends Neurosci 1985; 17: 487-493.
4. Cohen J. Programmed cell death in the immune system. Adv Immunol 1991; 50: 55-85.
5. Majno G, Joris I. Apoptosis, oncosis, and necrosis: an overview of cell death. Am J Pathol 1995; 146: 3-15.
6. Yuan J, Horvitz H. Genetic mosaic analysis of ced-3 and ced-4, two genes that control programmed cell death in the nematode. C. elegans. Dev Biol 1990; 138: 33-41.
7. McGeer P, Rogers J, McGeer E. Neuroimmune mechanisms in Alzheimer's disease pathogenesis. Alzheimer Dis Assoc Discord 1994; 8: 149-158.
8. Rothwell N, Hopkins S. Cytokines and the nervous system: actions and mechanisms of action. Trends Neurosci 1995; 18: 130-136.
9. Lassman H et al. Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropath 1995: 89: 35-41.
10. Portera-Cailliau C, Hedreen J, Price D, Koliatsos V. Evidence for apoptotic death in Huntington disease and excitotoxic animal models. J Neurosci 1995; 15: 3775-3787.
11. Rabizadeh S et al. Mutations associated with amyotropic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proc Natl Acad Sci USA 1995; 92: 3024-3028.
12. Estaquier J et al. Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc Natl Acad Sci USA 1994; 91: 9431-9435.
13. Linnik M, Zobrist R, Hatfield M. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 1993; 24: 2002-2009.
14. Cerretti D et al. Molecular cloning of the IL-1β converting enzyme. Science 1992; 256: 97-100.
15. Thornberry N et al. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 1992; 356: 768-774.
16. Walker N et al. Crystal structure of the cysteine protease interleukin-1β-converting enzyme: a (p20/p10)2 homodimer. Cell 1994; 78: 343-352.
17. Wilson K et al. Structure and mechanism of interleukin-1β converting enzyme. Nature 1994; 370: 270-275.
18. Howard A et al. IL-1β converting enzyme requires aspartic acid residues for processing of the IL-1β precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha. J Immunol 1991; 147: 2964-2969.
19. Sleath P et al. Substrate specificity of the protease that processes human interleukin-1β. J Biol Chem 1990; 265: 14526-14528.
20. Keane K et al. Cloning, tissue expression and regulation of rat interleukin-1β converting enzyme. Cytokine 1995; 7: 105.
21. Black R, Kornheim S, Sleath P. Activation of interleukin-1β by a co-induced protease. FEBS Lett 1989; 247: 386-390.
22. Kostura M et al. Identification of a monocyte specific pre-interleukin 1β convertase activity. Proc Natl Acad Sci USA 1989; 86: 5227-5231.
23. Vasilakos J et al. IL-1β converting enzyme (ICE) is not required for apoptosis induced by lymphokine deprivation in an IL-2-dependent T cell line. J Immunol 1995; 155: 3433-3442.
24. Li P et al. Mice deficient in interleukin-1β converting enzyme (ICE) are defective in production of mature interleukin-1β (IL-1β) and resistant to endotoxic shock. Cell 1995; 80: 401-411.
25. Shivers B et al. Distribution and regulation of interleukin-1β converting enzyme in rat and man. In: I Hannin, M Yoshida, A Fisher (eds). Alzheimer's and Parkinson's Diseases. Plenum Press: New York, 1995, pp 231-238.
26. Yuan J et al. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 1993; 75: 641-652.
27. Miura M et al. Induction of apoptosis in fibroblasts by IL-1β converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 1993; 75: 653-660.
28. Boudreau N, Sympson C, Werb Z, Bissell M. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 1995; 267: 891-893.
29. Kondo S et al. Interleukin-1β-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. Cancer Res 1995; 55: 6166-6171.
30. Kuida K et al. Altered cytokine export and apoptosis in mice deficient in IL-1β converting enzyme. Science 1995; 267: 2000-2003.
31. Biedler D et al. The baculovirus p35 protein inhibits fas-and tumour necrosis factor-induced apoptosis. J Biol Chem 1995; 270: 16526-16528.
32. Enari M, Hug H, Nagata S. Involvement of an ICE-like protease in fas-mediated apoptosis. Nature 1995; 375: 78-81.
33. Los M et al. Requirement of an ICE/CED-3 protease for fas/APO-1-mediated apoptosis. Nature 1995; 375: 81-83.
34. Tewari M, Dixit V. Fas- and tumor necrosis factor-induced apoptosis in inhibited by the poxvirus virus crmA gene product. J Biol Clin 1995; 270: 3255-3260.
35. Kumar S et al. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gone ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev 1994; 8: 1613-1626.
36. Wang L et al. Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 1994; 78: 739-750.
37. Kumar S. Inhibition of apoptosis by the expression of antisense Nedd2. FEBS Lett 1995; 368: 69-72.
38. Fernandos-Alnemri T, Litwack G, Alnemri E. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-convorting enzyme. J Biol Chem 1994; 269: 30761-30764.
39. Lazebnik Y et al. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Science 1994; 371: 346-347.
40. Nicholson D et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43.
41. Tewari M et al. Yama/CPP32β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymeraso. Cell 1995; 81: 801-809.
42. Wang X et al. Purification of an interleukin-1β converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains. J Biol Chem 1995; 270: 18044-18050.