The role of ancillary properties of beta-blockers;DE BETEKENIS VAN BIJKOMENDE EIGENSCHAPPEN VAN BETABLOKKERS. MET EEN LIPOFIELE SELECTIEVE BETABLOKKER ZIT MEN VRIJWEL ALTIJD GOED.

Pharmaceutisch Weekblad

Volumn 133, Issue 31, 1998, Pages 1134-1139

  Cleophas, T J ^a   Kauw, F H ^b   Van Der Meulen, J ^b   Kalmansohn, R B ^b  

^a Merwedeziekenhuis   (Netherlands)

^b NONE

Author keywords

Adrenergic beta antagonists; Intrinsic sympathicomimetic activity; Lipophilicity; Receptor affinity; Selectivity; Vasodilation

Indexed keywords

ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; BEVANTOLOL; BISOPROLOL; CARVEDILOL; CELIPROLOL; ESMOLOL; LABETALOL; METOPROLOL; NEBIVOLOL; OXPRENOLOL; PINDOLOL; PROPRANOLOL; SOTALOL; TERTATOLOL; TIMOLOL;

ANGINA PECTORIS; ARTICLE; CARDIOSELECTIVITY; CEREBROVASCULAR ACCIDENT; DRUG INDICATION; HEART FAILURE; HUMAN; HYPERTENSION; INTRINSIC SYMPATHOMIMETIC ACTIVITY; LIPOPHILICITY; ORTHOSTATIC HYPOTENSION; PRESSOR RESPONSE; RECEPTOR AFFINITY; VASODILATATION;

EID: 0032584778     PISSN: 00316911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Hoffman BB, Lefkowitz RJ. Beta-adrenergic receptor antagonists. In: Hardman JG, Limbird LE, Molinoff PB, et al, red. Goodman & Gillman's Pharmacological Basis of Therapeutics. New York: McGraw-Hill, 1996:232-48.
2. Wilhelmsen L, Berglund C, Elmfeldt D, et al. Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY Trial. J Hypertens 1987;5:561-72.
3. Soriano JB, Ferro A, Wilhelmi E. Increased survival with beta-blockers: importance of ancillary properties. Prog Cardiovasc Dis 1997;93:445-56.
4. Van den Meiracker AH, Man in 't Veld AJ, Ritsema van Eck HJ, et al. Hemodynamic and hormonal adaptations to beta-adrenoceptor blockade. Circulation 1988;78:957-68.
5. Man in 't Veld AJ, Schalekamp MADH. Pindolol acts as beta-adrenoceptor agonist in orthostatic hypotension. BMJ 1981;282:929-31.
6. Cleophas TJ, Kauw FH, Bijl CH. Effects of beta-adrenergic receptor agonists and antagonists in diabetics with symptoms of postural hypotension: a double blind placebo controlled study. Angiology 1986;37:855-62.
7. Brown MJ. To beta block or better block, selectivity rarely matters despite the hype. BMJ 1995;311:701-2.
8. Houston MC. New insights and new approaches for the treatment of essential hypertension: selection of therapy based on coronary heart disease risk factor analysis. Am Heart J 1989;117:911-51.
9. Cleophas TJ, Kauw FH. Pressor responses from noncardioselective beta-blockers. Angiology 1988,39:587-96.
10. Cleophas TJ, Kauw FH. More on paradoxical pressor effects of nonselective beta-blockers. Circulation 1994;90:2157-9.
11. Van Herwaarden CL. Selective and non-selective beta-blockade in hypertension [dissertatie]. Nijmegen: Katholieke Universiteit Nijmegen, 1978.
12. Houben H, Thien T, Van 't Laar A Effects of low-dose epinephrine infusion on hemodynamics after selective and non-selective beta-blockade in hypertension. Clin Pharmacol Ther 1982;31:685-90.
13. Cleophas TJM. Beta-blockers in hypertension and angina pectoris. Dordrecht: Kluwer Academic Publishers, 1995.
14. Cleophas TJ, Stappers GJ. A pressor effect of nonselective beta-blockers during acute hospitalization. Angiology 1990;41:125-32.
15. Cleophas TJ, Stappers GJ, Oudshoorn N, et al. A pressor effect of nonselective beta-blockers during surgery under anesthesia. Angiology 1991;42:805-11.
16. Cleophas TJ, Niemeyer MG, Zwinderman AH. A pressor effect of nonselective beta-blockade in unstable angina pectoris. Clin Pharmacol Ther 1995;57.50-6.
17. Packer M, Bristow MR, Cohn JN, et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 1996; 334:1349-55.
18. Cleophas TJ, Niemeyer MG, Kalmansohn RB. NO donors and angina pectoris, more than just symptomatic treatment. Neth J Med 1997;50:180-18.
19. Johnston GD, Vyssoulis G, Feely J, et al Effect of celiprolol and metoprolol on airways function in patients with asthma and obstructive lung disease. J Hum Hypertens 1995;9:123-7
20. Brodde OE. The functional importance of beta-1 and beta-2 adrenoceptors in the human heart. Am J Cardiol 1988;62:24-9C.
21. Saruta T, Kumagai H The sympathetic nervous system in hypertension and renal disease. Curr Opin Nephrol Hypertens 1996;5.72-9.
22. Shimkets RA, Lifton RP. Recent advances in the molecular genetics of hypertension. Curr Opin Nephrol Hypertens 1996;5:162-5
23. CAST Investigators, Preliminary report, effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989;321:406-12.
24. Brown MJ. Hazards of beta-blockade. Author's reply. BMJ 1996;11:165-8.
25. The Guidelines Subcommittee of the WHO/ISH Mild Hypertension Liaison Committee. 1993 guidelines for the management of mild hypertension: memorandum from a World Health Organization/International Society of Hypertension Meeting. Hypertension 1993;22:392-403.
26. Zanchetti A. Guidelines for the management of hypertension: the World Health Organization/International Society of Hypertension view. J Hypertens 1995;13 suppl:119-22.
27. Medical Research Council Working Party. Medical Research Council trial of treatment of hypertension in older adults: principal results. BMJ 1992,304:405-12.
28. Medical Research Council Working Party. MRC trial of mild hypertension: principal results. BMJ 1985;291:97-104.
29. The IPPPSH Collaborative Group. Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: the International Prospective Primary Prevention Study in Hypertension (IPPPSH). J Hypertens 1985;3 379-92.
30. Packer M, O'Connor CM, Ghall JK, et al. Effect of amlodipine on morbidity and mortality in severe chronic heart failure. N Engl J Med 1996,335:1107-14.
31. DEFIANT II Study Group. Doppler flow and echocardiography in functional cardiac insufficiency; assessment of nisoldipine therapy. Eur Heart J 1997;18:31-40.
32. CRIS Study Group. Calcium antagonist italian study. Am J Cardiol 1996;77 365-9
33. Gong L, Zhang W, Zhu Y. Shanghai trial of nifedipine in the elderly (STONE). J Hypertens 1996;14:1237-45.
34. Staessen JA, Fagard R, Thijs L, et al. Randomized double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997; 350:757-64.