β1 integrin deficiency impairs migration and differentiation of mouse embryonic stem cell derived neurons

Neuroscience Letters

Volumn 251, Issue 3, 1998, Pages 165-168

  Andressen, Christian ^a   Arnhold, Stefan ^a   Puschmann, Martin ^a   Bloch, Wilhelm ^a   Hescheler, Jürgen ^b   Fässler, Reinhard ^c   Addicks, Klaus ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell matrix interaction; Embryonic stem cells; Neurite outgrowth; Neuronal migration

Indexed keywords

4 AMINOBUTYRIC ACID; BETA1 INTEGRIN; GLUTAMIC ACID; INTEGRIN; NEUROTRANSMITTER; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CELL MIGRATION; EMBRYO; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; STEM CELL; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVE CELL; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD29; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; EMBRYO; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; MICE; NEURONS; STEM CELLS; SYNAPTOPHYSIN;

EID: 0032584388     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00535-7     Document Type: Article

References (26)

1. Angelov D.N., Arnhold S., Andressen C., Grabsch H., Puschmann M., Hescheler J., Addicks K. Temporospatial relationships between macroglia and microglia during in vitro differentiation of murine stem cells. Dev. Neurosci. 20:1998;42-51.
2. Bain G., Kitchens D., Yao M., Huettner J.E., Gottlieb D.I. Embryonic stem cells express neuronal properties in vitro. Dev. Biol. 168:1995;342-357.
3. Bloch W., Forsberg E., Lentini S., Brakebusch C., Martin K., Krell H.W., Weidle U.H., Addicks K., Fässler R. β1 integrin is essential for teratoma growth and angiogenesis. J. Cell Biol. 139:1997;265-278.
4. Carri N.G., Perris R., Johansson S., Ebendal T. Differential outgrowth of retinal neurites on purified extracellular matrix molecules. J. Neurosci. Res. 19:1988;428-439.
5. Doetschman T.C., Eistetter H., Katz M., Schmidt W., Kemler R. The in vitro development of blastocyst derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morph. 87:1985;27-45.
6. Dziadek M. Role of laminin-nidogen complexes in basement membrane formation during development. Experientia. 51:1995;901-913.
7. Fässler R., Meyer M. Consequences of lack of β1 integrin gene expression in mice. Genes Dev. 9:1995;1896-1908.
8. Fässler R., Pfaff M., Murphy J., Noegel A., Johansson S., Timpl R., Albrecht R. Lack of β1 integrin in embryonic stem cells affect morphology, adhesion, and migration, but not integration into the inner cell mass of blastocysts. J. Cell Biol. 128:1995;979-988.
9. Fässler R., Rohwedel J., Maltsev V., Bloch W., Lentini S., Guan K., Gullberg D., Hescheler J., Addicks K., Wobus A.M. Differentiation and integrity of cardiac muscle cells are impaired in the absence of β1 integrin. J Cell Sci. 109:1996;2989-2999.
10. Fraichard A., Chassande O., Bilbaut G., Dehay C., Savatier P., Samarut J. In vitro differentiation of embryonic stem cells into glia cells and functional neurons. J. Cell Sci. 108:1995;3181-3188.
11. Gumbiner B.M. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:1996;345-357.
12. Haas T.A., Plow E.F. Integrin-ligand interactions: a year in review. Curr. Opin. Cell Biol. 6:1994;656-662.
13. Hall H., Carbonetto S., Schachner M. L1/HNK-1 carbohydrate- and β1 integrin-dependent neural cell adhesion to laminin-1. J. Neurochem. 68:1997;544-553.
14. Hirsch E., Iglesias A., Potocnik A.J., Hartmann U., Fässler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins. Nature. 380:1996;171-175.
15. Hynes R.O. Integrins: versatility, modulation, and signalling in cell adhesion. Cell. 69:1992;11-25.
16. Letourneau P.C., Condick M.L., Snow D.M. Interactions of developing neurons with the extracellular matrix. J. Neurosci. 14:1994;915-928.
17. Letourneau P.C. Extracellular matrix and neurite outgrowth. Curr. Opin. Genet. Dev. 2:1992;625-634.
18. McKerracher L., Chamoux M., Arregui C.O. Role of laminin and integrin interactions in growth cone guidance. Mol. Neurobiol. 12:1996;95-116.
19. Reichardt L.F., Tomaselli K.J. Extracellular matrix molecules and their receptors: functions in neural development. Ann. Rev. Neurosci. 14:1991;531-570.
20. Rossino P., Defilippi P., Silengo L., Tarone G. Up-regulation of the integrin α1/β1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin. Cell Regul. 2:1991;1021-1033.
21. Sakaguchi D.S., Radke K. β1 integrins regulate axon outgrowth and glial cell spreading on a glial derived extracellular matrix during development and regeneration. Dev. Brain Res. 97:1996;235-250.
22. Sanes J. Extracellular matrix molecules that influence neural development. Ann. Rev. Neurosci. 12:1989;491-516.
23. Schwartz M.A. Signalling by integrins: implications for tumorigenesis. Cancer Res. 53:1993;1503-1506.
24. Strübing C., Ahnert-Hilgert G., Shan J., Wiedenmann B., Hescheler J.K., Wobus A.M. Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons. Mech. Dev. 53:1995;275-287.
25. Timpl R., Brown J.C. The laminins. Matrix Biol. 14:1994;13729-13732.
26. Yamazaki T., Koo E.H., Selkoe D.J. Cell surface amyloid β protein precursor colocalizes with β1 integrins at substrate contact sites in neural cells. J. Neurosci. 17:1997;1004-1010.