Active site modifications in a double mutant of liver alcohol dehydrogenase: Structural studies of two enzyme - Ligand complexes

Biochemistry

Volumn 37, Issue 26, 1998, Pages 9295-9304

  Colby, Thomas D ^a   Bahnson, Brian J ^b,c   Chin, Jodie K ^b   Klinman, Judith P ^b   Goldstein, Barry M ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; TRIFLUOROETHANOL;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; HORSE; HYDROGEN BOND; LIGAND BINDING; LIVER CELL; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; QUANTUM MECHANICS;

ALANINE; ALCOHOL DEHYDROGENASE; ALCOHOL OXIDOREDUCTASES; ANIMALS; BINDING SITES; COENZYMES; CRYSTALLOGRAPHY, X-RAY; HORSES; LIGANDS; LIVER; MODELS, MOLECULAR; NAD; NIACINAMIDE; PHENYLALANINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRYPTOPHAN; VALINE;

ANIMALIA; EQUUS CABALLUS;

EID: 0032580981     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi973184b     Document Type: Article

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