Synthesis and aldose reductase inhibitory activity of benzoyl-amino acid derivatives

Farmaco

Volumn 53, Issue 6, 1998, Pages 439-442

  Benvenuti, Stefania ^a   Severi, Fabio ^a   Costantino, Luca ^a   Vampa, Gabriella ^a   Melegari, Michele ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Aldose reductase inhibitors; Benzoyl L amino acid derivatives

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; AMINO ACID DERIVATIVE; QUERCETIN; SORBINIL; TOLRESTAT;

ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; LENS; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; ULTRAVIOLET SPECTROPHOTOMETRY;

ALDEHYDE REDUCTASE; AMINO ACIDS; ANIMALS; CATTLE; ENZYME INHIBITORS; LENS, CRYSTALLINE;

EID: 0032580926     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(98)00038-X     Document Type: Article

References (13)

1. [1] C.R. Rasmussen, B.E. Maryanoff, G.F. Tutwiler, Section IV, Metabolie diseases and endocrin function. Ch. 17, Diabetes mellitus, Ann. Rep. Med. Chem. 16 (1981) 173-187.
2. [2] M. Brownlee, A. Cerami, The biochemistry of the complications of diabetes mellitus, Ann. Rev. Biochem. 50 (1981) 385-432.
3. [3] P.F. Kador, The role of aldose reductase in the development of diabetic complications, Med. Res. Rev. 8 (1988) 325-352.
4. [4] R. Sarges, P.J. Dates, Aldose reductase inhibitors: recent developments, Prog. Drug Res. 40 (1993) 99-161.
5. [5] P.F. Kador, J.H. Kinoshita, N.E. Sharpless, Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications, J. Med. Chem. 28 (1985) 841-849.
6. [6] J. De Ruiter, B.E. Swearingen, V. Wandrekar, C.A. Mayfield, Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety, J. Med. Chem. 32 (1989) 1033-1038.
7. [7] K. Sestanj, F. Bellini, S. Fung, N. Abraham, A. Treasurywala, L. Humber, N. Simard-Duquesns, D. Dvornik, N-[[5-(Trifluoromethyl)-6-methoxy-1-naphthalenyl]-N-methylglycine (Tolrestat), a potent orally active aldose reductase inhibitor, J. Med. Chem. 26 (1984) 255-256.
8. [8] L. Costantino, G. Rastelli, K. Vescovini, G. Cignarella, P. Vianello, A. Del Corso, M. Cappiello, U. Mura, D. Barlocco, Synthesis, activity, and molecular modelling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors, J. Med. Chem. 39 (1996) 4396-4405.
9. [9] A. Del Corso, M. Camici, U. Mura, In vitro modification of bovine lens aldose reductase activity, Biochem. Biophys. Res. Commun. 148 (1987) 369-375.
10. [10] W.H.J. Ward, C.M. Sennitt, H. Ross, A. Dingle, D. Timms, D.J. Mirrlees, D.P. Tuffin, Ponalrestat: a potent and specific inhibitor of aldose reductase, Biochem. Pharmacol. 39 (1990) 337-346.
11. [11] H.G. Bray, M. Valda, S. Craddock, M.W. Thorpe, Biochem. J. 60 (1955) 225 [Beilstein 10, IV, 435].
12. [12] N. Friedler, J.N. Smith, Biochem. J. 57 (1954) 396 [Beilstein, 9, IV, 1199].
13. [13] M. Van der Schear, S. Landsteiner, J. Immunol. 29 (1935) 371 [Beilstein, 14, III, 1523].