Regulation of G protein-mediated adenylyl cyclase in striatum and cortex of opiate-dependent and opiate withdrawing mice

Brain Research

Volumn 788, Issue 1-2, 1998, Pages 104-110

  Kaplan, Gary B ^a   Leite Morris, Kimberly A ^a   Sethi, Rajiv K ^a   McClelland, Eric G ^a  

^a PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Adenosine 3',5' cyclic phosphate; Adenylyl cyclase; G protein; Morphine; Opiate dependence; Opiate withdrawal; Opioid receptor

Indexed keywords

ADENYLATE CYCLASE; GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; OPIATE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DRUG WITHDRAWAL; ENZYME ACTIVITY; ENZYME ANALYSIS; MALE; MOUSE; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; WITHDRAWAL SYNDROME;

ADENYLATE CYCLASE; ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL CORTEX; CORPUS STRIATUM; FORSKOLIN; GTP-BINDING PROTEINS; LOGISTIC MODELS; MALE; MICE; MICE, INBRED STRAINS; MORPHINE; MORPHINE DEPENDENCE; SUBSTANCE WITHDRAWAL SYNDROME; TELENCEPHALON;

EID: 0032579824     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01524-2     Document Type: Article

References (40)

1. Ammer H., Schulz R. Alterations in the expression of G-proteins and regulation of adenylate cyclase in human neuroblastoma SH-SY5Y cells chronically exposed to low-efficacy mu-opioids. Biochem. J. 295:1993;263-271.
2. sα and opioid peptide mRNA levels in discrete brain regions. J. Neurosci. Res. 36:1993;551-557.
3. Bassareo V., Tanda G., DiChiara G. Increase of extracellular dopamine in the medial prefrontal cortex during spontaneous and naloxone-precipitated opiate abstinence. Psychopharmacology. 122:1995;202-205.
4. Breivogel C.S., Selley D.E., Childers R. Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes. J. Neurochem. 68:1997;1462-1472.
5. Chakrabarti S., Law P., Loh H.H. Neuroblastoma Neuro2A cells stably expressing a cloned mu-opioid receptor: a specific cellular model to study acute and chronic effects of morphine. Mol. Brain Res. 30:1995;269-278.
6. Chen J., Rasenick M.M. Chronic antidepressant treatment facilitates G protein activation of adenylyl cyclase without altering G protein content. J. Pharmacol. Exp. Ther. 275:1995;509-517.
7. Crippens D., Robinson T. Withdrawal from morphine or amphetamine: different effects on dopamine in the ventral-medial striatum studied with microdialysis. Brain Res. 650:1994;56-62.
8. DiChiara G., North R.A. Neurobiology of opiate abuse. TiPS. 13:1992;185-193.
9. Duman R.S., Tallman J.F., Nestler E.J. Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus. J. Pharmacol. Exp. Ther. 246:1988;1033-1039.
10. Eriksson P.S., Carlsson B., Isaksson O.G.P., Hansson E., Ronnback L. Altered amounts of G-protein mRNA and cAMP accumulation after long-term opioid receptor stimulation of neurons in primary culture from the rat cerebral cortex. Mol. Brain Res. 14:1992;317-325.
11. Escriba P.V., Sastre M., Garcia-Sevilla J.A. Increased density of guanine nucleotide-binding proteins in the postmortem brains of heroin addicts. Arch. Gen. Psychiatry. 51:1994;494-501.
12. i-protein beta-gamma subunits. Nature. 356:1992;159-161.
13. Ingram S.L., Williams J.T. Opioid inhibition of Ih via adenylyl cyclase. Neuron. 13:1994;179-186.
14. Izenwasser S., Buzas B., Cox B.M. Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens. J. Pharmacol. Exp. Ther. 267:1993;145-152.
15. Kaplan G.B., Leite-Morris K.A. Up-regulation of adenosine transporter-binding sites in striatum and hypothalamus of opiate tolerant mice. Brain Res. 763:1997;215-220.
16. Kaplan G.B., Sears M.T. Adenosine receptor agonists attenuate and adenosine receptor antagonists exacerbate opiate withdrawal signs. Psychopharmacology. 123:1996;64-70.
17. Kaplan G.B., Leite-Morris K.A., Sears M.T. Alterations of adenosine A1 receptors in morphine dependence. Brain Res. 657:1994;347-350.
18. Karreman M., Moghaddam B. The prefrontal cortex regulates the basal release of dopamine in the limbic striatum: an effect mediated by ventral tegmental area. J. Neurochem. 66:1996;589-598.
19. Lane-Ladd S.B., Pineda J., Boundy V.A., Pfeuffer T., Krupinski J., Aghajanian G.K., Nestler E.J. CREB (cAMP Response Element-Binding Protein) in the locus coeruleus: biochemical, physiological, and behavioral evidence for a role in opiate dependence. J. Neurosci. 17:1997;7890-7901.
20. Law P.Y., Hom D.S., Loh H.H. Loss of opiate receptor activity in neuroblastoma×glioma NG 108-15 hybrid cells after chronic opiate treatment. Mol. Pharmacol. 22:1982;1-4.
21. Mackler S.A., Eberwine J.H. Cellular adaptation to opiates alters ion-channel mRNA levels. Proc. Natl. Acad. Sci. 91:1994;385-389.
22. Matsuoka I., Maldonado R., Defer N., Noel F., Hanoune J., Roques B.-P. Chronic morphine administration causes region-specific increase of brain type VIII adenylyl cyclase mRNA. Eur. J. Pharmacol. 268:1994;215-221.
23. G. Milligan, Identification and analysis of function of heterotrimeric guanine nucleotide-binding proteins expressed in neuronal tissue, in: A.A. Boulton, G.B. Baker, C.W. Taylor (Eds.), Neuromethods, Humana Press, Totowa, NJ, 1992, pp. 1-56.
24. K.J. Murray, Methods in cyclic nucleotide research, in: A.A. Boulton, G.B. Baker, C.W. Taylor (Eds.), Neuromethods, Humana Press, Totowa, NJ, 1992, pp. 313-368.
25. Nestler E.J. Molecular mechanisms of drug addiction. J. Neurosci. 12:1992;2439-2450.
26. Nestler E.J., Erdos J.J., Terwilliger R., Duman R.S., Tallman J.F. Regulation of G proteins by chronic morphine in the rat locus coeruleus. Brain Res. 476:1989;230-239.
27. Noble F., Cox B.M. Differential desensitization of mu- and delta-opioid receptors in selected neural pathways following chronic morphine treatment. Br. J. Pharmacol. 117:1996;161-169.
28. oα mRNA in discrete brain regions of morphine-tolerant rats. Eur. J. Pharmacol. 244:1993;211-222.
29. Rasmussen K., Beitner-Johnson D.B., Krystal J.H., Aghajanian G.K., Nestler E.J. Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates. J. Neurosci. 10:1990;2308-2317.
30. Rubino T., Massi P., Patrini G., Venier I., Giagnoni G., Parolaro D. Effect of chronic exposure to naltrexone and opioid selective agonists on G protein mRNA levels in the rat nervous system. Mol. Brain Res. 23:1994;333-337.
31. Rubino T., Parenti M., Patrini G., Massi P., Parolaro D. Morphine withdrawal syndrome and G protein expression: a study of the time course in the rat central nervous system. Eur. J. Neurosci. 7:1995;2334-2340.
32. o proteins in nucleus accumbens reduces both cocaine and heroin reinforcement. J. Neurosci. 14:1994;6239-6247.
33. Self D.W., McClenahan A.W., Beitner-Johnson D., Terwilliger R.Z., Nestler E.J. Biochemical adaptations in the mesolimbic dopamine system in response to heroin self-administration. Synapse. 21:1995;312-318.
34. Sharma S.K., Klee W.A., Nirenberg M. Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc. Natl. Acad. Sci. U.S.A. 72:1975;3092-3096.
35. Simonato M. The neurochemistry of morphine addiction in the neocortex. TiPS. 17:1996;410-415.
36. sα. Biochemistry. 33:1994;12852-12859.
37. Terwilliger R.Z., Beitner-Johnson D., Sevarino K.A., Crain S.M., Nestler E.J. A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function. Brain Res. 548:1991;100-110.
38. Tremblay E.C., Charton G. Anatomical correlates of morphine-withdrawal syndrome: differential participation of structures located within the limbic system and striatum. Neurosci. Lett. 23:1981;137-142.
39. Valverde O., Tzavara E., Hanoune J., Roques B.P., Maldonado R. Protein kinases in the rat nucleus accumbens are involved in the aversive component of opiate withdrawal. Eur. J. Neurosci. 8:1996;2671-2678.
40. i-proteins underlie adenylyl cyclase sensitization in morphine-treated rat striatal neurons. Eur. J. Pharmacol. 245:1993;23-29.