Homotropic activation via the subunit interaction and allosteric symmetry revealed on analysis of hybrid enzymes of L-lactate dehydrogenase

Journal of Biological Chemistry

Volumn 273, Issue 5, 1998, Pages 2971-2976

  Fushinobu, Shinya ^a   Ohta, Takahisa ^a,b   Matsuzawa, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KOGAKUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LACTATE DEHYDROGENASE;

ALLOSTERISM; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; LACTOBACILLUS BIFIDUS; PRIORITY JOURNAL;

BIFIDOBACTERIUM; ENZYME ACTIVATION; ISOENZYMES; ISOMERISM; KINETICS; L-LACTATE DEHYDROGENASE; MALATE DEHYDROGENASE; MODELS, BIOLOGICAL; MUTATION; OXALOACETATES; OXALOACETIC ACIDS; PROTEIN HYBRIDIZATION; PYRUVIC ACID; RECOMBINANT PROTEINS;

EID: 0032579247     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.5.2971     Document Type: Article

References (23)

1. Gerhart, J. C., and Pardee, A. B. (1962) J. Biol. Chem. 237, 891-896
2. Foote, J., and Schachman, H. K. (1985) J. Mol. Biol. 186, 175-184
3. Holbrook, J. J., Liljas, A., Steindel, S. J., and Rossmann, M. G. (1975) in The Enzymes (Boyer, P. D., ed) 3rd Ed., Vol. 11, pp. 191-292, Academic Press, New York
4. Garvie, E. I. (1980) Microbiol. Rev. 44, 106-139
5. Minowa, T., Iwata, S., Sakai, H., Masaki, H., and Ohta, T. (1989) Gene (Amst.) 85, 161-168
6. Iwata, S., Minowa, T., Sakai, H., and Ohta, T. (1989) Agric. Biol. Chem. 53, 3365-3366
7. Iwata, S., Kamata, K., Yoshida, S., Minowa, T., and Ohta, T. (1994) Nat. Struct. Biol. 1, 176-185
8. Iwata, S., and Ohta, T. (1993) J. Mol. Biol. 230, 21-27
9. Rossmann, M. G., Adams, M. J., Buehner, M., Ford, G. C., Hackert, M. L., Liljas, A., Rao, S. T., Banaszak, L. J., Hill, E., Tsernoglou, D., and Webb, L. (1973) J. Mol. Biol. 76, 533-537
10. Monod, J., Wyman, J., and Changeux, J.-P. (1965) J. Mol. Biol. 12, 88-118
11. Fushinobu, S., Kamata, K., Iwata, S., Sakai, H., Ohta, T., and Matsuzawa, H. (1996) J. Biol. Chem. 271, 25611-25616
12. Ohta, T., Yokota, K., Minowa, T., and Iwata, S. (1992) Faraday Discuss. 93, 153-161
13. Wilks, H. M., Hart, K. W., Feeney, R., Dunn, C. R., Muirhead, H., Chia, W. N., Barstow, D. A., Atkinson, T., Clarke, A. R., and Holbrook, J. J. (1988) Science 242, 1541-1544
14. Iwata, S., Minowa, T., Mikami, B., Morita, Y., and Ohta, T. (1989) J. Biochem. (Tokyo) 106, 558-559
15. Dixon, M., and Webb, E. C. (1979) in Enzymes, 3rd Ed., pp. 400-402, Longman, London
16. Perutz, M. F. (1989) Mechanisms of Cooperativity and Allosteric Regulation in Proteins, Cambridge University Press, Cambridge, England
17. Yang, Y. R., and Schachman, H. K. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 5187-5191
18. Mattevi, A., Rizzi, M., and Bolognesi, M. (1996) Curr. Opin. Struct. Biol. 6, 824-829
19. Zhang, Y., Liang, J.-Y., Huang, S., and Lipscomb, W. N. (1994) J. Mol. Biol. 244, 609-624
20. Ackers, G. K., and Hazzard, J. H. (1993) Trends Biochem. Sci. 18, 385-390
21. Mattevi, A., Bolognesi, M., and Valentini, G. (1996) FEBS Lett. 389, 15-19
22. Bloom, C. R., Choi, W. E., Brzovic, P. S., Ha, J. J., Huang, S.-T., Kaarsholm, N. C., and Dunn, M. F. (1995) J. Mol. Biol. 245, 324-330
23. Eventoff, W., Rossmann, M. G., Taylor, S. S., Torff, H.-J., Meyer, H., Keil, W., and Kiltz, H.-H. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 2677-2681