Dominant-negative mutants of the SH2/SH3 adapters Nck and Grb2 inhibit MAP kinase activation and mesoderm-specific gene induction by eFGF in Xenopus

Oncogene

Volumn 17, Issue 17, 1998, Pages 2155-2165

  Gupta, Ruchika W ^a,b   Mayer, Bruce J ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

FGF; MAPK; Mesoderm induction; SH2 SH3 adapters

Indexed keywords

ADAPTOR PROTEIN; FIBROBLAST GROWTH FACTOR; MESODERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; GENE INDUCTION; GENE MUTATION; GENE TARGETING; MESODERM; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

ANIMALIA; XENOPUS; XENOPUS LAEVIS;

EID: 0032578801     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202158     Document Type: Article

References (61)

1. Chou MM and Hanafusa H. (1995). J. Biol. Chem., 270, 7359-7364.
2. Christian JL, McMahon JA, McMahon AP and Moon RT. (1991). Development, 111, 1045-1055.
3. Clark SG, Stern MJ and Horvitz HR. (1992). Nature, 356, 340-344.
4. Cohen GB and Baltimore D. (1995). Cell, 80, 237-248.
5. Dent P, Haster W, Haystead TAJ, Vincent LA, Roberts TM and Sturgill TW. (1992). Science, 257, 1404-1407.
6. Fantl WJ, Johnson DE and Williams LT. (1993). Annu. Rev. Biochem., 62, 453-481.
7. Feller SM, Knudson B and Hanafusa H. (1995). Oncogene, 18, 1465-1473.
8. Gomez N and Cohen P. (1991). Nature, 353, 170-173.
9. Gotoh T, Hattori S, Nakamura S, Kitayama H, Noda M, Takai Y, Kaibuchi K, Matsui H, Hatase O, Takahashi H, et al. (1995a). Mol. Cell. Biol., 15, 6746-6753.
10. Gotoh Y, Masuyama N, Suzuki A, Ueno N and Nishida E. (1995b). EMBO J., 14, 2491-2498.
11. Harlow E and Lane D. (1988). Antibodies, a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
12. Her JH, Lakhani S, Zu K, Vila J, Dent P, Sturgill TW and Weber MJ. (1993). Biochem. J., 296, 25-31.
13. Hu G, Milfay D and Williams LT. (1995). Mol. Cell. Biol., 15, 1169-1174.
14. Hughes DA, Ashworth A and Marshall CJ. (1993). Nature, 364, 349-352.
15. Isaacs HV, Tannahill D and Slack JM. (1992). Development, 114, 711-720.
16. Johnson DE and Williams LT. (1993). Adv. Cancer Res., 60, 1-41.
17. Kimelman D, Abraham JA, Haaparanta T, Palisi TM and Kirschner MW. (1988). Science, 242, 1053-1056.
18. Kimelman D and Kirschner M. (1987). Cell, 51, 869-877.
19. Kitamura T, Kitamura Y, Yonezawa K, Totty NF, Gout I, Hara K, Waterfield MD, Sakaue M, Ogawa W and Kasuga M. (1996). Biochem. Biophys. Res. Commun., 219, 509-514.
20. Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y and Noda M. (1989). Cell, 56, 77-84.
21. Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I and Schlessinger J. (1997). Cell, 89, 693-702.
22. Krieg PA and Melton DA. (1984). Nucl. Acids Res., 12, 7057-7070.
23. Krieg PA, Varnum SM, Wormington WM and Melton DA. (1989). Dev. Biol., 133, 93-100.
24. Kyriakis JM, App H, Zhang XF, Banerjee P, Brautigan DL, Rapp UR and Avruch J. (1992). Nature, 358, 417-421.
25. L'Allemain G, Her GH, Wu J, Sturgill TW and Weber MJ. (1992). Mol. Cell. Biol., 12, 2222-2229.
26. LaBonne C, Burke B and Whitman M. (1995). Development, 121, 1475-1486.
27. Lu W, Katz S, Gupta R and Mayer BJ. (1997). Curr. Biol., 7, 85-94.
28. MacDonald SG, Crews CM, Wu L, Driller J, Clark R, Erikson RL and McCormick F. (1993). Mol. Cell. Biol., 13, 6615-6620.
29. MacNicol AM, Muslin AJ and Williams LT. (1993). Cell, 73, 571-583.
30. Mason IJ. (1994). Cell, 78, 547-552.
31. Mohammedi M, Dionne CA, Li W, Li N, Spivak T, Honnegger AM, Jaye M and Schlessinger J. (1992). Nature 358, 681-684.
32. Muslin AJ, Peters G and Williams LT. (1994). Mol. Cell. Biol., 14, 3006-3012.
33. Nakeilny S, Cohen P, Wu J and Sturgill TW. (1992). EMBO J., 11, 2123-2129.
34. Newport J and Kirschner M. (1982). Cell, 30, 675-686.
35. Nieuwkoop PD and Faber J. (1967). Normal table of Xenopus laevis. North-Holland: Amsterdam.
36. Okada S and Pessin JE. (1996). J. Biol. Chem., 271, 25533-25538.
37. Olivier JP, Raabe T, Henkemeyer M, Dickson B, Mbamalu G, Margolis B, Schlessinger J, Hafen E and Pawson T. (1993). Cell, 73, 179-191.
38. Pawson T. (1995). Nature, 373, 573-579.
39. Pellman D, Garber EA, Cross RR and Hanafusa H. (1985). Nature, 314, 374-377.
40. Peters KG, Marie J, Wilson E, Ives HE, Escobedo J, Del Rosario M, Mirda D and Williams LT. (1992). Nature, 358, 678-681.
41. Quilliam LA, Lambert QT, Mickelson-Young LA, Westwick JK, Sparks AB, Kay BK, Jenkins NA, Gilbert DJ, Copeland NG and Der CJ. (1996). J. Biol. Chem., 271, 28772-28776.
42. Rivero-Lezcano OM, Marcilla A, Sameshima JH and Robbin SKC. (1995). Mol. Cell. Biol., 15, 5725-5731.
43. Rivero-Lezcano OM, Sameshima JH, Marcilla A and Robbins KC. (1994). J. Biol. Chem., 269, 17363-17366.
44. Rockow S, Tang J, Xiong W and Li W. (1996). Oncogene, 12, 2351-2359.
45. Rossomando AJ, Sanghera JS, Marsden LA, Weber MJ, Pelech SL and Sturgill TW. (1991). J. Biol. Chem., 266, 20270-20275.
46. Ryan PJ and Gillespie LL. (1994). Dev. Biol., 166, 101-111.
47. Schlaepler DD, Broome MA and Hunter T. (1997). Mol. Cell. Biol., 17, 1702-1713.
48. Simon MA, Dodson GS and Rubin GM. (1993). Cell, 73, 169-177.
49. Slack J, Darlington BG, Heath JK and Godsave SF. (1987). Nature, 326, 197-200.
50. Smith JC, Price BMJ, Green JBA, Weigel D and Herrmann BG. (1991). Cell, 67, 79-87.
51. Spencer DM, Graef I, Austin DJ, Schreiber SL and Crabtree GR. (1995). Proc. Natl. Acad. Sci. USA, 92, 9805-9809.
52. Stern MJ, Marengere LEM, Daly RJ, Lowenstein EJ, Kokel M, Batzer A, Olivier P, Pawson T and Schlessinger J. (1993). Mol. Cell. Biol., 4, 1175-1188.
53. Tanaka M, Gupta R and Mayer BJ. (1995). Mol. Cell. Biol., 15, 6829-6837.
54. Tanaka M, Lu W, Gupta R and Mayer BJ. (1997). Proc. Natl. Acad. Sci. USA, 94, 4493-4498.
55. Tanaka S, Morishita T, Hashimoto Y, Hattori S, Nakamura S, Shibuya M, Matuoka K, Takenawa T, Kurata T, Nagashima K and Matsuda M. (1994). Proc. Natl. Acad. Sci. USA, 91, 3443-3447.
56. Teng KK, Lander H, Fajardo JE, Hanafusa H, Hempstead BL and Birge RB. (1995). J. Biol. Chem., 270, 20677-20685.
57. Ullrich A and Schlessinger J. (1990). Cell, 61, 203-212.
58. Umbhauer M, Marshall CJ, Mason CS, Old RW and Smith JC. (1995). Nature, 376, 58-62.
59. Vize PD, Melton DA, Hemmati-Brivanlou A and Harland RM. (1991). Meth. Cell. Biol., 36, 367-387.
60. Ward CW, Gough KH, Rashke M, Wan SS, Tribbick G and Wang J-x. (1996). J. Biol. Chem., 271, 5603-5609.
61. Whitman M and Melton DA. (1992). Nature, 357, 252-254.