Transport of fragmented DNA in apical dendrites of gerbil CA1 pyramidal neurons following transient fore ischemia

Brain Research

Volumn 806, Issue 2, 1998, Pages 274-277

  Hara, Akira ^a   Niwa, Masayuki ^a   Iwai, Tomohiko ^a   Nakashima, Masaya ^a   Yano, Hirohito ^a   Uematsu, Toshihiko ^a   Yoshimi, Naoki ^a   Mori, Hideki ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apical dendrite; Delayed neuronal death; DNA fragmentation; Fore ischemia; Gerbil

Indexed keywords

CELL DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITE; DNA CONTENT; DNA DEGRADATION; FOREBRAIN; GERBIL; INTRACELLULAR TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; PYRAMIDAL NERVE CELL;

ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; DENDRITES; DNA; DNA FRAGMENTATION; GERBILLINAE; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; MALE; PYRAMIDAL CELLS;

EID: 0032576018     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00753-7     Document Type: Article

References (21)

1. Collins J.A., Schandi C.A., Young K.K., Vesely J., Willingham M.C. Major DNA fragmentation is a late event in apoptosis. J. Histochem. Cytochem. 45:1997;923-934.
2. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
3. Gilbert S.P., Allen R.D., Sloboda R.D. Translocation of vesicles from squid axoplasm on flagellar microtubules. Nature. 315:1985;245-248.
4. Grafstein B., Forman D.S. Intracellular transport in neurons. Physiol. Rev. 60:1980;1168-1283.
5. Hara A., Yoshimi N., Hirose Y., Ino N., Tanaka T., Mori H. DNA fragmentation in granular cells of human cerebellum following global ischemia. Brain Res. 697:1995;247-250.
6. Hara A., Yoshimi N., Mori Y.H., Iwai T., Sakai N., Yamada H., Niwa M. Hypothermic prevention of nuclear DNA fragmentation in gerbil hippocampus following transient forebrain ischemia. Neurol. Res. 17:1995;461-464.
7. A. Hara, M. Niwa, M. Nakashima, T. Iwai, T. Uematsu, N. Yoshimi, H. Mori, Protective effect of apoptosis-inhibitory agent, N-tosyl-L-phenylalanyl chloromethyl ketone against ischemia-induced hippocampal neuronal damage, J. Cereb. Blood Flow Metab., 1998, in press.
8. Heron A., Pollard H., Dessi F., Moreau J., Lasbennes F., Ben-Ari Y., Charriaut-Marlangue C. Regional variability in DNA fragmentation after global ischemic evidenced by combined histological and gel electrophoresis observations in the rat brain. J. Neurochem. 61:1993;1973-1976.
9. Howard J. Molecular motors: structural adaptations to cellular functions. Nature. 389:1997;561-567.
10. Iwai T., Hara A., Niwa M., Nozaki M., Uematsu T., Sakai N., Yamada H. Temporal profile of nuclear DNA fragmentation in situ in gerbil hippocampus following transient forebrain ischemia. Brain Res. 671:1995;305-308.
11. Kass G.E., Eriksson J.E., Weis M., Orrenius S., Chow S.C. Chromatin condensation during apoptosis requires ATP. Biochem. J. 318:1996;749-752.
12. Kato H., Kogure K., Araki T., Itoyama Y. Graded expression of immunomolecules on activated microglia in the hippocampus following ischemia in a rat model of ischemic tolerance. Brain Res. 694:1995;85-93.
13. Levee M.G., Dabrowska M.I., Lelli J.L. Jr., Hinshaw D.B. Actin polymerization and depolymerization during apoptosis in HL-60 cells. Am. J. Physiol. 271:1996;1981-1992.
14. MacManus J.P., Buchan A.M., Hill I.E., Rasquinha I., Preston E. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci. Lett. 164:1993;89-92.
15. Morioka T., Kalehua A.N., Streit W.J. Progressive expression of immunomolecules on microglial cells in rat dorsal hippocampus following transient forebrain ischemia. Acta Neuropathol. 83:1992;149-157.
16. Nitatori T., Sato N., Waguri S., Karasawa Y., Araki H., Shibanai K., Kominami E., Uchiyama Y. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. 15:1995;1001-1011.
17. Niwa M., Hara A., Iwai T., Nakashima M., Yano H., Yoshimi N., Mori H., Uematsu T. Relationship between magnitude of hypothermia during ischemia and preventive effect against post-ischemic DNA fragmentation in the gerbil hippocampus. Brain Res. 794:1998;338-342.
18. Petito C.K., Torres-Munoz J., Roberts B., Olarte J.P., Nowak T.S. Jr., Pulsinelli W.A. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat. J. Cereb. Blood Flow Metab. 17:1997;967-976.
19. Wang Z., Khan S., Sheetz M.P. Single cytoplasmic dynein molecule movements: characterization and comparison with kinesin. Biophys. J. 69:1995;2011-2023.
20. Weisenberg R.C., Flynn J., Gao B.C., Awodi S., Skee F., Goodman S.R., Riederer B.M. Microtubule gelation-contraction: essential components and relation to slow axonal transport. Science. 238:1987;1119-1122.
21. Yasumoto Y., Passonneau J.V., Feussner G., Lust W.D. Metabolic alterations in fiber and somal layers of the CA1 regions of the gerbil hippocampus following short-term ischemia: high-energy phosphates, glucose-related metabolites and amino acids. Metab. Brain Dis. 3:1998;133-150.