Metabolic alterations in fiber layers of the CA 1 region of the gerbil hippocampus following short-term ischemia: High-energy phosphates, glucose-related metabolites, and amino acids

Metabolic Brain Disease

Volumn 3, Issue 2, 1988, Pages 133-149

  Yasumoto, Yukimasa ^a   Passonneau, Janet V ^b   Feussner, Gretchen ^b   Lust, W David ^c  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ATP; energy metabolism; GABA; glucose; ischemia; selective vulnerability

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; GLUTAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN ISCHEMIA; ENERGY METABOLISM; GERBIL; GLUCOSE METABOLISM; HIPPOCAMPUS; NONHUMAN;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMAL; BRAIN ISCHEMIA; CEREBRAL CORTEX; ENERGY METABOLISM; GAMMA-AMINOBUTYRIC ACID; GERBILLINAE; GLUCOSE; GLUTAMINE; GLYCOGEN; HIPPOCAMPUS; NERVE FIBERS; NEURONS; PHOSPHATES;

EID: 0023875115     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/BF01001014     Document Type: Article

References (51)

1. Two different responses of hippocampal pyramidal cells to application of GABA
2. Energy metabolism in delayed neuronal death of CA1 Neurons of the hippocampus following transient ischemia in the gerbil
3. The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers
4. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
5. The distribution of glycine, GABA, glutamate and aspartate in rabbit spinal cord, cerebellum and hippocampus
6. Glutamate and glutamine distribution in the rat nephron in acidosis and alkalosis
7. Increased 2-deoxyglucose uptake in hippocampus, globus pallidus and substantia nigra after cerebral ischemia
8. Hippocampus: Synaptic pharmacology
9. Complete cerebral ischaemia in the rat: An ultrastructural and stereological analysis of the distal stratum radiatum in the hippocampal CA-1 region
10. Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates and associated amino acids in the rat cerebral cortex
11. Low dose of barbiturates for prevention of hippocampal lesions after brief ischemie episodes
12. Removal of the entorhinal cortex protects hippocampal CA-1 neurons from ischemie damage
13. Delayed neuronal death in the gerbil hippocampus following ischemia
14. Selective vulnerability of the hippocampus to ischemiareversible and irreversible types of ischemic cell damage
15. A reversible type of neuronal injury following ischemia in the gerbil hippocampus
16. Some morphological and biochemical aspects of abnormal glycogen accumulation in the glia
17. Concentrations of energy metabolites and cyclic nucleotides during and after bilateral ischemia in the gerbil cerebral cortex
18. Reduced ATP concentration as a basis for synaptic transmission failure during hypoxia in the in vitro guinea pig hippocampus
19. Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia
20. The enzymatic measurement of adenine nucleotides and P-creatine in picomole amounts
21. Metabolite levels in brain following experimental seizures: The effects of maximal electroshock and phenytoin in cerebellar layers
22. Metabolite levels in brain following experimental seizures: The effects of isoniazid and valproate in cerebellar and cerebral cortical layers
23. Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters
24. Postischemic changes in certain metabolites following prolonged ischemia in the gerbil cerebral cortex
25. Effect of 5-minute ischemia on regional pH and energy state of the gerbil brain: Relation to selective vulnerability of the hippocampus
26. Interactions between neurons and glia in glutamate/ glutamine compartmentation
27. Lesions to Schaffer collaterals prevent ischemie death of CA-1 pyramidal cells
28. Some aspects of intermediary metabolism in glioma cells in culture
29. Delayed Neuronal recovery and neuronal death in rat hippocampus following severe cerebral ischemia: Possible relationship to abnormalities in neuronal processes
30. Barbiturate-induced glycogen accumulation in brain. An electron microscopic study
31. Optimal freezing conditions for cerebral metabolites in rats
32. Dopamine and ischemie striatal nerve cell death
33. Regional energy balance in rat brain after transient forebrain ischemia
34. Temporal profile of neuronal damage in a model of transient forebrain ischemia
35. Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia
36. Glutamate and the pathophysiology of hypoxic-ischemic brain damage
37. Excitotoxicity and the NMDA receptor
38. Blockade of N-methyl-D-aspartate receptors may protect against ischemie damage in the brain
39. The [14C]2-deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure and normal values in the conscious and anesthetized rat
40. Erkrankung des Ammonshorns als aetiologisches Moment der Epilepsie
41. Pharmacological protection of against delayed neuronal death elicited by ischemia
42. Glutamate in hippocampal pathways. Glutamate as a neurotransmitter
43. The effects of 5-minute ischemia in Mongolian gerbils. I. Blood-brain barrier, cerebral blood flow and local cerebral glucose utilization changes
44. The effects of 5-minute ischemia in Mongolian gerbils. II. Changes of spontaneous neuronal activity in cerebral cortex and CA-1 sector of hippocampus
45. Sitz und Wesen der Krankheiten im Lichte der topistischen Hirnforschung und des Variierens der Tiere
46. Cerebral synaptic transmission during anoxia is protected by creatine
47. Hippocampal cell death following ischemia in the gerbil: Electrophysiological results obtained in vitro
48. Delayed metabolic changes in hippocampal layers following transient ischemia in the gerbil