β-Amino-thiols inhibit the zinc metallopeptidase activity of tetanus toxin light chain

Journal of Medicinal Chemistry

Volumn 41, Issue 18, 1998, Pages 3450-3460

  Martin, Loïc ^a   Cornille, Fabrice ^a   Coric, Pascale ^a   Roques, Bernard P ^a   Fournié Zaluski, Marie Claude ^a  

^a Laboratoire de Pharmacochimie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BETA AMINO (4 SULFAMOYLPHENYL)GLYCINE THIOL; NEUROTOXIN INHIBITOR; TETANUS TOXIN; UNCLASSIFIED DRUG; ZINC METALLOPEPTIDASE; ZINC METALLOPEPTIDASE INHIBITOR;

ARTICLE; BOTULISM; CLOSTRIDIUM TETANI; ENZYME ACTIVITY; EXOCYTOSIS; INFECTION PREVENTION; INHIBITION KINETICS; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ENZYME INHIBITORS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; NERVE TISSUE PROTEINS; R-SNARE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; SULFONAMIDES; TETANUS TOXIN; ZINC;

EID: 0032572832     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm981015z     Document Type: Article

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