Survival of accommodated cardiac xenografts upon retransplantation into cyclosporine-treated recipients

Transplantation

Volumn 65, Issue 12, 1998, Pages 1563-1569

  Miyatake, Tsukasa ^a   Koyamada, Nozomi ^b   Hancock, Wayne W ^c   Soares, Miguel P ^f   Bach, Fritz H ^d,e  

^a HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

^e HARVARD MEDICAL SCHOOL   (United States)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL PROTECTION; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HAMSTER; HEART GRAFT; HEART TRANSPLANTATION; HELPER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; SPECIES DIFFERENCE; VASCULARIZATION; XENOGRAFT;

ANIMALS; COBRA VENOMS; CRICETINAE; CYCLOSPORINE; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOSUPPRESSIVE AGENTS; MALE; MESOCRICETUS; POLYENES; RATS; RATS, INBRED LEW; REOPERATION; SIROLIMUS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0032572260     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199806270-00005     Document Type: Article

References (22)

1. Bach FH, Ferran C, Hechenleitner P, et al. Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment. Nature Med 1997; 3(2): 196.
2. Hasan R, Van den Bogaerde JB, Wallwork J, White DJ. Evidence that long-term survival of concordant xenografts is achieved by inhibition of antispecies antibody production. Transplantation 1992; 54(3): 408.
3. Anrather J, Csizmadia V, Brostjan C, Soares MP, Bach FH, Winkler H. Inhibition of bovine endothelial cell activation in vitro by regulated expression of a transdominant inhibitor of NF-kappa B. J Clin Invest 1997; 99(4): 763.
4. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers [Review]. FASEB J 1995; 9(10): 899.
5. Cooper JT, Stroka DM, Brostjan C, Palmetshofer A, Bach FH, Ferran C. A20 blocks endothelial cell activation through a NF-kappa B-dependent mechanism. J Biol Chem 1996; 271(30): 18068.
6. Xiao F, Chong AS, Foster P, et al. Leflunomide controls rejection in hamster to rat cardiac xenografts. Transplantation 1994; 58(7): 828.
7. Lin Y, Vandeputte M, Waer M. Natural killer cell- and macrophage-mediated rejection of concordant xenografts in the absence of T and B cell responses. J Immunol 1997; 158(12): 5658.
8. 7a. Miyatake T, Sato K, Takigami K, et al. Complement fixing elicited antibodies are a major component in the pathogenesis of xenograft rejection. J Immunol 1998; 160: 4114.
9. Soares M, Havaux X, Nisol F, Bazin H, Latinne D. Modulation of rat B cell differentiation in vivo by the administration of an anti-μ monoclonal antibody. J Immunol 1996; 156: 108.
10. Bach FH, Winkler H, Ferran C, Hancock WW, Robson SC. Delayed xenograft rejection [Review]. Immunol Today 1996; 17(8): 379.
11. Platt JL. Xenotransplantation: recent progress and current perspectives. [Review]. Curr Opin Immunol 1996; 8(5): 721.
12. Parker W, Saadi S, Lin SS, Holzknecht ZE, Bustos M, Platt JL. Transplantation of discordant xenografts: a challenge revisited [Review]. Immunol Today 1996; 17(8): 373.
13. Saadi S, Holzknecht RA, Patte CP, Stern DM, Platt JL. Complement-mediated regulation of tissue factor activity in endothelium. J Exp Med 1995; 182(6): 1807.
14. Saadi S, Platt JL. Transient perturbation of endothelial integrity induced by natural antibodies and complement. J Exp Med 1995; 181(1): 21.
15. Bach FH, Robson SC, Ferran C, et al. Endothelial cell activation and thromboregulation during xenograft rejection [Review]. Immunol Rev 1994; 141(5): 5.
16. Parker W, Lundberg SK, Holzknecht ZE, et al. Isohemagglutinins and xenoreactive antibodies: members of a distinct family of natural antibodies. Human Immunol 1996; 45(2): 94.
17. Platt JL, Bach FH. Discordant xenografting: challenges and controversies [Review]. Curr Opin Immunol 1991; 3(5): 735.
18. Bach FH, Turman MA, Vercellotti GM, Platt JL, Dalmasso AP. Accommodation: a working paradigm for progressing toward clinical discordant xenografting [Review]. Transplant Proc 1991; 23(1 Pt 1): 205.
19. Alexandre GP, Squifflet JP, De BM, et al. Present experiences in a series of 26 ABO-incompatible living donor renal allografts. Transplant Proc 1987; 19(6): 4538.
20. Bach FH, Hancock WW, Ferran C. Protective genes in endothelial cells: a regulatory response to injury. Immunol Today 1998; 18: 483.
21. Platt JL, Bach FH. The barrier to xenotransplantation [Review]. Transplantation 1991; 52(6): 937.
22. Cooper JT, Stroka DM, Brostjan C, Palmetshofer A, Bach FH, Ferran C. A20 expression inhibits endothelial cell activation. Transplantation Proc 1997; 29: 881.