Anxiolytic effects of flesinoxan in the stress-induced hyperthermia paradigm in singly-housed mice are 5-HT(1A) receptor mediated

European Journal of Pharmacology

Volumn 342, Issue 2-3, 1998, Pages 177-182

  Olivier, Berend ^a,b   Zethof, Theo J J ^a   Ronken, Eric ^a,b   Van Der Heyden, Jan A M ^a  

^a Solvay Pharmaceuticals Inc   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

(Mouse); 5 HT(1A) receptor; DU 125530; Flesinoxan, enantiomer; Hyperthermia, stress induced; WAY 100635

Indexed keywords

ANXIOLYTIC AGENT; FLESINOXAN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR;

ANIMAL EXPERIMENT; ANXIETY NEUROSIS; ARTICLE; DRUG EFFECT; DRUG RECEPTOR BINDING; HYPERTHERMIA; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTI-ANXIETY AGENTS; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTHERMIA, INDUCED; MALE; MICE; PIPERAZINES; PYRIDINES; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SOCIAL ISOLATION; STEREOISOMERISM; STRESS, PSYCHOLOGICAL; THIAZOLES;

EID: 0032567711     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01482-9     Document Type: Article

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