Platelet-activating factor receptor antagonist attenuates endotoxin- induced vascular hyporeactivity in the pithed rat

European Journal of Pharmacology

Volumn 342, Issue 2-3, 1998, Pages 241-245

  Yoshikawa, Daisuke ^a   Shiga, Tatsuya ^a   Saito, Shigeru ^a   Morita, Toshihiro ^a   Imai, Takasuke ^a   Goto, Fumio ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Endotoxin; N(G) Monomethyl L arginine; Noradrenaline; PAF (platelet activating factor); TCV 309; Vascular hyporeactivity

Indexed keywords

3 BROMO 5 [N PHENYL N [2 [[2 (1,2,3,4 TETRAHYDRO 2 ISOQUINOLYLCARBONYLOXY)ETHYL]CARBAMOYL]ETHYL]CARBAMOYL] 1 PROPYLPYRIDINIUM NITRATE; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; SODIUM CHLORIDE; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL ANIMAL;

ANIMALS; BLOOD PRESSURE; BLOOD VESSELS; DECEREBRATE STATE; ENDOTOXINS; ENZYME INHIBITORS; ISOQUINOLINES; MALE; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; OMEGA-N-METHYLARGININE; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; PYRIDINIUM COMPOUNDS; RATS; RATS, WISTAR; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; TETRAHYDROISOQUINOLINES; VASOCONSTRICTOR AGENTS;

EID: 0032567704     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01513-6     Document Type: Article

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