Increased expression of liver PKC α in hypoinsulinemic diabetic rats: A post-translational effect

Molecular and Cellular Endocrinology

Volumn 146, Issue 1-2, 1998, Pages 177-185

  Nivet, V ^a   Antoine, P J ^b   Amessou, M ^c   Descamps, G ^a   Desbuquois, B ^c   Clot, J P ^c   Durand, D ^a  

^a Faculte de Pharmacie   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Diabetic rats; Insulin; Liver subcellular fractions; Phlorizin; PKC mRNA; STZ

Indexed keywords

MESSENGER RNA; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; HYPOINSULINEMIA; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; CELL NUCLEUS; CYTOSOL; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION; INSULIN; ISOENZYMES; LIVER; MALE; MICROSOMES, LIVER; MITOCHONDRIA, LIVER; PHLORHIZIN; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0032567198     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(98)00155-5     Document Type: Article

References (37)

1. Aronson N.N., Touster O. Isolation of rat liver plasma membranes fragments in isotonic sucrose. Methods Enzymol. 31:1974;90-102.
2. Avignon A., Yamada K., Zhou X. et al. Chronic activation of protein kinase C in soleus muscles and others tissues of insulin-resistant type II diabetic goto-kakizaki (GK); obese/aged; and obese/Zucker rats. Diabetes. 45:1996;1396-1404.
3. Borner C., Filipuzzi I., Wartmann M., Eppenberger U., Fabbro D. Biosynthesis and posttranslational modifications of protein kinase C in human breast cancer cells. J. Biol. Chem. 264:1989;13902-13909.
4. Cazaubon S., Bornancin F., Parker P.J. Threonine-497 is a critical site for permissive activation of protein kinase C α Biochem. J. 301:1994;443-448.
5. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
6. Considine RV., Nyce M.R., Allen L.E. et al. Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia. J. Clin. Invest. 95:1995;2938-2944.
7. Cooper D.R., Konda T.S., Standaert M.L., Davis J.S., Pollet J.R., Farese R.V. Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes. J. Biol. Chem. 262:1987;3633-3639.
8. Cooper D.R., Hernandez H., Kuo J.Y., Farese R.V. Insulin increases the synthesis of phospholipid and diacylglycerol and protein kinase C activity in rat hepatocytes. Arch. Biochem. Biophys. 276:1990;486-494.
9. Craven P.A., Derubertis F.R. Protein kinase C is activated in glomeruli from streptozotocin diabetic rats: possible mediation by glucose. J. Clin. Invest. 83:1989;1667-1675.
10. Croquet F., Brehier A., Gil S., Davy J., Feger J. Five isoenzymes of protein kinase C are expressed in normal and STZ-diabetic rat hepatocytes: effect of phorbol 12myristate 13-acetate. Biochim. Biophys. Acta. 1315:1996;163-168.
11. Derubertis F.R., Craven P.A. Activation of protein kinase C in glomerular cells in diabetes. Diabetes. 43:1994;1-8.
12. Errol J.K., Rushovich H., Thomas T.P., Ueda T., Agranoff B.W., Green D. Diminished specific activity of cytosolic protein kinase C in sciatic nerve of streptozotocin-induced diabetic rats and its correction by dietary myo-inositol. Diabetes. 40:1991;1545-1554.
13. Garcia-Paramio P., Carmena M.J., Gutierrez-Ocana M.T., Recio M.N., Prieto J.C. Biochem. Biophys. Res. Commun. 195:1993;166-172.
14. Gatti A., Wang X., Robinson P.J. Protein kinase C α is multiply phosphorylated in response to phorbol ester stimulation of PC 12 cells. Biochim. Biophys. Acta. 1313:1996;111-118.
15. Gatti A., Robinson P.J. Unique phosphorylation of Protein kinase C α in PC 12 cells induces resistance to translocation and downregulation. J. Biol. Chem. 271:1996;31718-31722.
16. Hise M.K., Mehta P.S. Characterization and localization of calcium/phospholipid-dependent protein kinase-C during diabetic renal growth. Endocrinology. 123:1988;1553-1558.
17. Hoffman J.M., Ishizuka T., Farese R.V. Interrelated effects of insulin and glucose on diacylglycerol protein kinase C signaling in rat adipocytes and solei muscle in vitro and in vivo in diabetic rats. Endocrinology. 128:1991;2937-2948.
18. Inoguchi T., Battan R., Handler E., Sportsman J.R., Heath W., King G.L. Preferential elevation of protein kinase C isoform β2 and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc. Natl. Acad. Sci. USA. 89:1992;11059-11063.
19. Inoguchi T., Xia P., Kunisaki M., Higashi S., Feener E., King G.L. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues. Am. J. Physiol. 267:1994;E369-E379.
20. Ishizuka T., Cooper D.R., Farese R.V. Insulin stimulates the translocation of protein kinase C in rat adipocytes. FEBS Lett. 257:1989;337-340.
21. Ishizuka T., Cooper D.R., Hernandez H., Buckley D., Standaert M., Farese R.V. Effects of insulin on diacylglycerol-protein kinase C signaling in rat diaphragm and soleus muscles and relationship to glucose transport. Diabetes. 39:1990;181-190.
22. Lee T.S., Saltsman K.A., Ohashi H., King G.L. Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc. Natl. Acad. Sci. USA. 86:1989;5141-5145.
23. Lee H.W., Smith L., Pettit G.R., Vinitsky A., Smith J.B. Ubiquitination of protein kinase C-alpha and degradation by the proteasome. J. Biol. Chem. 271:1996;20973-20976.
24. Newton A.C. Protein kinase C: structure, function, and regulation; minireview. J. Biol. Chem. 270:1995;28495-28498.
25. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
26. Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses; serial review. Protein kinase C and lipid signaling for sustained cellular responses; serial review. 9:1995;484-496.
27. Nivet V., Clot J.P., Do X.T., Barrault V., Prelot M., Durand D. Evidence that growth hormone stimulates protein kinase C activity in isolated hepatocytes. Metabolism. 42:1993;1291-1295.
28. 3H]PDBu binding using a 96-well microtiter plate and a cell harvester. 184:1990;283-290.
29. Pears C., Stabel S., Cazaubon S., Parker P.J. Studies on the phosphorylation of protein kinase C α Biochem. J. 283:1992;515-518.
30. Perletti G.P. Partial purification of protein kinase C isoenzymes from rat liver. J. Biochem. Biophys. Methods. 28:1994;195-204.
31. Pugazhenti S., Mantha S.V., Khandelwal R.L. Decrease of liver protein kinase C in streptozotocin-induced diabetic rats and restoration by vanadate treatment. Biochem. Int. 21:1990;651-657.
32. Robles-Flores M., Alcantara-Hernandez R., Garcia-Sainz J.A. Differences in phorbol ester-induced decrease of the activity of protein kinase C isozymes in rat hepatocytes. Biochim. Biophys. Acta. 1094:1991;77-84.
33. Tang E.Y., Parker P.J., Beattie J., Houslay M.D. Diabetes induces selective alterations in the expression of protein kinase C isoforms in hepatocytes. FEBS Lett. 326:1993;117-123.
34. Wetsel W.C., Khan C.A., Merchenthaler I. et al. Tissue and cellular distribution of the extended family of protein kinase C isoenzymes. J. Cell. Biol. 117:1992;121-133.
35. Xiang H., Macneil J.H. Protein kinase C activity is altered in diabetic rat hearts. Biochem. Biophys. Res. Commun. 187:1992;703-710.
36. Young S., Parker P.J., Ullrich A., Stabel S. Downregulation of protein kinase C is due to an increased rate of degradation. Biochem. J. 244:1987;775-779.
37. Zimmermann K., Mannhalter WM. Technical aspects of quantitative competitive PCR. Biotechniques. 21:1996;268-279.