메뉴 건너뛰기




Volumn 400, Issue 1-2, 1998, Pages 3-14

Functional genomics in the post-genome era

Author keywords

DNA chips; ENU mutagenesis; Functional genomics; Gene expression; Microhomologous recombination

Indexed keywords

DNA; ETHYLNITROSOUREA;

EID: 0032565542     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00023-2     Document Type: Article
Times cited : (46)

References (47)
  • 4
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global views of biology
    • [4] E.S. Lander, The new genomics: global views of biology, Science 274 (1996) 536-539.
    • (1996) Science , vol.274 , pp. 536-539
    • Lander, E.S.1
  • 11
    • 0031235029 scopus 로고    scopus 로고
    • Analysis of biosensor chips for identification of nucleic acids
    • [11] H.F. Arlinghaus, M.N. Kwoka, K.B. Jacobson, Analysis of biosensor chips for identification of nucleic acids, Anal. Chem. 69 (1997) 3747-3753.
    • (1997) Anal. Chem. , vol.69 , pp. 3747-3753
    • Arlinghaus, H.F.1    Kwoka, M.N.2    Jacobson, K.B.3
  • 12
    • 0031569494 scopus 로고    scopus 로고
    • Multiplexed DNA sequencing and diagnostics by hybridization with enriched stable isotope labels
    • [12] H.F. Arlinghaus, M.N. Kwoka, X.Q. Guo, K.B. Jacobson, Multiplexed DNA sequencing and diagnostics by hybridization with enriched stable isotope labels, Anal. Chem. 69 (1997) 1510-1517.
    • (1997) Anal. Chem. , vol.69 , pp. 1510-1517
    • Arlinghaus, H.F.1    Kwoka, M.N.2    Guo, X.Q.3    Jacobson, K.B.4
  • 14
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • [14] K.R. Thomas, M.R. Capecchi, Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells, Cell 51 (1987) 503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 16
    • 0028222953 scopus 로고
    • Targeting frequency for deletion vector in embryonic stem cells
    • [16] H. Zhang, P. Hasty, A. Bradley, Targeting frequency for deletion vector in embryonic stem cells, Mol. Cell. Biol. 14 (1994) 4389-4397.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4389-4397
    • Zhang, H.1    Hasty, P.2    Bradley, A.3
  • 17
    • 0031570713 scopus 로고    scopus 로고
    • Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: Establishment of new HPRT-deficient mouse embryonic stem cell lines
    • [17] H. Tsuda, C.E. Maynard-Currie, L.H. Reid, T. Yoshida, K. Edamura, N. Maeda, O. Smithies, A. Jakobovits, Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines, Genomics 42 (1997) 413-421.
    • (1997) Genomics , vol.42 , pp. 413-421
    • Tsuda, H.1    Maynard-Currie, C.E.2    Reid, L.H.3    Yoshida, T.4    Edamura, K.5    Maeda, N.6    Smithies, O.7    Jakobovits, A.8
  • 18
    • 0029562967 scopus 로고
    • Chromosome engineering in mice
    • [18] R. Ramirez-Solis, P. Liu, A. Bradley, Chromosome engineering in mice, Nature 378 (1995) 720-724.
    • (1995) Nature , vol.378 , pp. 720-724
    • Ramirez-Solis, R.1    Liu, P.2    Bradley, A.3
  • 19
    • 0026100231 scopus 로고
    • Testing an 'in-out' targeting procedure for making subtle genomic modifications in mouse embryonic stem cells
    • [19] V. Valancius, O. Smithies, Testing an 'in-out' targeting procedure for making subtle genomic modifications in mouse embryonic stem cells, Mol. Cell. Biol. 11 (1991) 1402-1408.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1402-1408
    • Valancius, V.1    Smithies, O.2
  • 20
    • 0025943412 scopus 로고
    • The length of homology required in embryonic stem cells
    • [20] P. Hasty, J. Rivera-Perez, A. Bradley, The length of homology required in embryonic stem cells, Mol. Cell. Biol. 11 (1991) 5586-5591.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5586-5591
    • Hasty, P.1    Rivera-Perez, J.2    Bradley, A.3
  • 21
    • 0030608379 scopus 로고    scopus 로고
    • Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting
    • [21] L.R. Toth, T.J. Smith, C. Jones, H.V. de Silva, O. Smithies, N. Maeda, Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting, Genetics 161 (1996) 161-168.
    • (1996) Genetics , vol.161 , pp. 161-168
    • Toth, L.R.1    Smith, T.J.2    Jones, C.3    De Silva, H.V.4    Smithies, O.5    Maeda, N.6
  • 22
    • 0027316203 scopus 로고
    • Site-directed point mutation in embryonic stem cells: A gene-targeting tag-and-exchange strategy
    • [22] G.R. Askew, T. Doetschman, J.B. Lingrel, Site-directed point mutation in embryonic stem cells: a gene-targeting tag-and-exchange strategy, Mol. Cell. Biol. 13 (1993) 4115-4124.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4115-4124
    • Askew, G.R.1    Doetschman, T.2    Lingrel, J.B.3
  • 23
    • 0028333746 scopus 로고
    • Double replacement: Strategy for efficient introduction of a subtle mutation into the murine Colla-1 gene by homologous recombination in embryonic stem cells
    • [23] H. Wu, X. Liu, R. Jaenisch, Double replacement: strategy for efficient introduction of a subtle mutation into the murine Colla-1 gene by homologous recombination in embryonic stem cells, Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 2819-2823.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2819-2823
    • Wu, H.1    Liu, X.2    Jaenisch, R.3
  • 24
    • 0030806247 scopus 로고    scopus 로고
    • Introduction of precise alterations into the mouse genome with high efficiency by stable tag-exchange gene targeting: Implications for gene targeting in ES cells
    • [24] L. Whyatt, P.D. Rathjen, Introduction of precise alterations into the mouse genome with high efficiency by stable tag-exchange gene targeting: implications for gene targeting in ES cells, Nucl. Acids Res. 25 (1997) 2381-2388.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 2381-2388
    • Whyatt, L.1    Rathjen, P.D.2
  • 25
    • 0027938450 scopus 로고
    • Deletion and replacement of the mouse adult β-globin genes by a 'plug and socket' repeated targeting strategy
    • [25] P.J. Detloff, J. Lewis, S.W.M. John, W.R. Shehee, R. Langenbach, N. Maeda, O. Smithies, Deletion and replacement of the mouse adult β-globin genes by a 'plug and socket' repeated targeting strategy, Mol. Cell. Biol. 14 (1994) 6936-6943.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6936-6943
    • Detloff, P.J.1    Lewis, J.2    John, S.W.M.3    Shehee, W.R.4    Langenbach, R.5    Maeda, N.6    Smithies, O.7
  • 27
    • 0029120399 scopus 로고
    • Micro-homology mediated PCR targeting in Saccharomyces cerevisiae
    • [27] P. Manivasakam, S.C. Weber, J. McElver, R.H. Schiestl, Micro-homology mediated PCR targeting in Saccharomyces cerevisiae, Nucl. Acids Res. 23 (1995) 2799-2800.
    • (1995) Nucl. Acids Res. , vol.23 , pp. 2799-2800
    • Manivasakam, P.1    Weber, S.C.2    McElver, J.3    Schiestl, R.H.4
  • 32
    • 0029859602 scopus 로고    scopus 로고
    • Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse
    • [32] T. Storck, U. Kruth, R. Kolhekar, R. Sprengel, P.H. Seeburg, Rapid construction in yeast of complex targeting vectors for gene manipulation in the mouse, Nucl. Acids Res. 24 (1996) 4594-4596.
    • (1996) Nucl. Acids Res. , vol.24 , pp. 4594-4596
    • Storck, T.1    Kruth, U.2    Kolhekar, R.3    Sprengel, R.4    Seeburg, P.H.5
  • 34
    • 0022369586 scopus 로고
    • Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia
    • [34] S. Hitotsumachi, D.A. Carpenter, W.L. Russell, Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia, Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 6619-6621.
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 6619-6621
    • Hitotsumachi, S.1    Carpenter, D.A.2    Russell, W.L.3
  • 36
    • 0025095309 scopus 로고
    • A strategy for line-structure functional analysis of a 6-to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis
    • [36] E.M. Rinchik, D.A. Carpenter, P.B. Selby, A strategy for line-structure functional analysis of a 6-to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis, Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 896-900.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 896-900
    • Rinchik, E.M.1    Carpenter, D.A.2    Selby, P.B.3
  • 37
    • 0025964682 scopus 로고
    • Chemical mutagenesis and fine-structure functional analysis of the mouse genome
    • [37] E.M. Rinchik, Chemical mutagenesis and fine-structure functional analysis of the mouse genome, Trends Genet. 7 (1991) 15-21.
    • (1991) Trends Genet. , vol.7 , pp. 15-21
    • Rinchik, E.M.1
  • 38
    • 0031414346 scopus 로고    scopus 로고
    • Using targeted large deletions and high-efficiency N-ethyl-N-nitosourea mutagenesis for functional analyses of the mammalian genome
    • M.F. Seldin (Ed.), Academic Press, in press
    • [38] M.J. Justice, B. Zheng, R.P. Woychik, A. Bradley, Using targeted large deletions and high-efficiency N-ethyl-N-nitosourea mutagenesis for functional analyses of the mammalian genome, in: M.F. Seldin (Ed.), Methods: A Companion to Methods in Enzymology, Vol. 13, Academic Press, in press.
    • Methods: A Companion to Methods in Enzymology , vol.13
    • Justice, M.J.1    Zheng, B.2    Woychik, R.P.3    Bradley, A.4
  • 41
    • 0025679209 scopus 로고
    • Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice
    • [41] T. Yokoyama, D.W. Silversides, K.G. Waymire, B.S. Kwon, T. Takeuchi, P.A. Overbeek, Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice, Nucl. Acids Res. 18 (1990) 7293-7298.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 7293-7298
    • Yokoyama, T.1    Silversides, D.W.2    Waymire, K.G.3    Kwon, B.S.4    Takeuchi, T.5    Overbeek, P.A.6
  • 43
    • 0030042726 scopus 로고    scopus 로고
    • Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants
    • [43] G.T. Kucera, D.Z. Bortner, M.P. Rosenberg, Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants, Dev. Biol. 173 (1996) 162-173.
    • (1996) Dev. Biol. , vol.173 , pp. 162-173
    • Kucera, G.T.1    Bortner, D.Z.2    Rosenberg, M.P.3
  • 44
    • 0031024091 scopus 로고    scopus 로고
    • Spectrum of Bmp5 mutations from germline mutagenesis experiments in mice
    • [44] P.C. Marker, K. Seung, A.E. Bland, L.B. Russell, D.M. Kingsley, Spectrum of Bmp5 mutations from germline mutagenesis experiments in mice, Genetics 145 (1997) 435-443.
    • (1997) Genetics , vol.145 , pp. 435-443
    • Marker, P.C.1    Seung, K.2    Bland, A.E.3    Russell, L.B.4    Kingsley, D.M.5
  • 45
    • 0023940354 scopus 로고
    • Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations
    • [45] M.J. Justice, V.C. Bode, Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations, Genet. Res. 51 (1988) 95-102.
    • (1988) Genet. Res. , vol.51 , pp. 95-102
    • Justice, M.J.1    Bode, V.C.2
  • 47
    • 0029962816 scopus 로고    scopus 로고
    • DNA chips: Analysing sequence by hybridization to oligonucleotides on a large scale
    • [47] E.M. Southern, DNA chips: analysing sequence by hybridization to oligonucleotides on a large scale, Trends Genet. 12 (1996) 110-115.
    • (1996) Trends Genet. , vol.12 , pp. 110-115
    • Southern, E.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.