Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting

Gene

Volumn 178, Issue 1-2, 1996, Pages 161-168

  Toth, Lori R ^a   Smith, Terry J ^a,c   Jones, Caroline ^a   De Silva, Harshini V ^b   Smithies, Oliver ^a   Maeda, Nobuyo ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

ES cells; Gene targeting; Homologous recombination; HPRT minigene; LDL receptor; Lipid metabolism

Indexed keywords

APOLIPOPROTEIN B; BETA GLOBIN; CHOLESTEROL; GENE PRODUCT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LOW DENSITY LIPOPROTEIN RECEPTOR; TIOGUANINE; TRIACYLGLYCEROL;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA RECOMBINATION; DRUG RESISTANCE; EMBRYO CELL; EXENCEPHALY; GENE DISRUPTION; GENE INSERTION; GENE LOCUS; GENE TARGETING; GENETIC RECOMBINATION; HOMOZYGOTE; HYDROCEPHALUS; HYPOLIPOPROTEINEMIA; LIPID METABOLISM; LIPOPROTEIN SECRETION; MOUSE; NONHUMAN; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SOUTHERN BLOTTING; STEM CELL; TRIACYLGLYCEROL BLOOD LEVEL;

ALOCASIA MACRORRHIZOS; ANIMALIA; MURINAE;

EID: 0030608379     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(96)00360-5     Document Type: Article

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