Conformational differences of an immunosuppressant peptolide in a single crystal and in a crystal complex with human cyclophilin A

Journal of Molecular Biology

Volumn 283, Issue 2, 1998, Pages 451-461

  Mikol, Vincent ^a   Taylor, Paul ^a   Kallen, Joerg ^a   Walkinshaw, Malcolm D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cyclophilin; Cyclosporin A; Immunophilin; Ligand binding; Peptolide 214103

Indexed keywords

AMIDE; CYCLOPHILIN A; CYCLOSPORIN DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; SDZ 214 103; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG PROTEIN BINDING; HYDROGEN BOND; LIGAND BINDING; PRIORITY JOURNAL; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

EID: 0032561129     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2109     Document Type: Article

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