Transient hypothermia induces micronuclei in mice

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 413, Issue 1, 1998, Pages 7-14

  Asanami, S ^a   Shimono, K ^a   Kaneda, S ^a  

^a Naruto Research Institute   (Japan)

Author keywords

Body temperature; Chlorpromazine; Hypothermia; In vitro chromosome aberration test; Micronucleus; Mouse

Indexed keywords

CHLORPROMAZINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CHROMOSOME ABERRATION; CONTROLLED STUDY; ERYTHROCYTE; HYPOTHERMIA; MICRONUCLEUS; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MARROW; CELL LINE; CHLORPROMAZINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; HYPOTHERMIA; MALE; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE;

EID: 0032559672     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00004-7     Document Type: Article

References (22)

1. Schmid W. Chemical mutagen testing on in vivo somatic mammalian cells. Agents and Actions. 3:1973;77-85.
2. Schmid W. The micronucleus test. Mutat. Res. 31:1975;9-15.
3. Heddle J.A. A rapid in vivo test for chromosomal damage. Mutat. Res. 18:1973;187-190.
4. Heddle J.A., Cimino M.C., Hayashi M., Romagna F., Shelby M.D., Tucker J.D., Vanparys Ph., MacGregor J.T. Micronuclei as an index of cytogenetic damage: past, present and future. Mol. Environ. Mutagen. 18:1991;277-291.
5. Hayashi M., Tice R.R., MacGregor J.T., Anderson D., Blakey D.H., Kirsh-Volders M., Oleson F.B. Jr., Pacchierotti F., Romagna F., Shimada H., Sutou S., Vannier B. In vivo rodent erythrocyte micronucleus assay. Mutat. Res. 312:1994;293-304.
6. Asanami S., Shimono K. High body temperature induces micronuclei in mouse bone marrow. Mutat. Res. 390:1997;79-83.
7. Asanami S., Shimono K. Hypothermia induces micronuclei in mouse bone marrow cells. Mutat. Res. 393:1997;91-98.
8. Parton J.W., Garriott M.L., Beyers J.E. Expulsion of demecolcine-induced micronuclei from mouse bone marrow polychromatic erythrocytes. Environ. Mol. Mutagen. 17:1991;79-83.
9. Boschi G., Launay N., Rips R. Neuro-induced hypothermia in mice: lack of evidence for a central mechanism. Br. J. Pharmacol. 90:1987;745-751.
10. M. Ishidate, Jr. (Eds.), Data Book of Chromosomal Aberration Test In Vitro, Rev. edn., Life-Science Information Center, Tokyo, Japan, 1987, p. 95.
11. Gocke E. Review of the genotoxic properties of chlorpromazine and related phenothiazines. Mutat. Res. 366:1996;9-21.
12. Sofuni T., Matsushima A., Shimada M., Ishidate M. Jr., Zeiger E., Shelby M.D. A comparison of chromosome aberration induction by 25 compounds tested by two Chinese hamster cell (CHL and CHO) systems in culture. Mutat. Res. 241:1990;175-213.
13. I. Yoshimura (Eds.), Statistical Analysis of Toxicity and Drug Efficacy Data, Scientist, Tokyo, 1987, pp. 76-78, in Japanese.
14. Hayashi M., Sofuni T., Ishidate M. Jr. An application of acridine orange fluorescent staining to the micronucleus test. Mutat. Res. 120:1983;241-247.
15. CSGMT (Collaborative Study Group for the Micronucleus Test), Micronucleus test with peripheral blood erythrocytes by acridine orange by supravital staining: the summary reports of 5th collaborative study by CSGMT/MMS, Mutat. Res. 278, (1992) 83-98.
16. Yamamoto K., Kikuchi Y. A comparison of diameters of micronuclei induced by clastogens and by spindle poisons. Mutat. Res. 71:1980;127-131.
17. Kastenbaum M.A., Bowman K.O. Tables for determining the statistical significance of mutation frequencies. Mutat. Res. 9:1970;527-549.
18. Dunnett C.W. A multiple comparison procedure for comparing several treatments with control. J. Am. Statist. Assoc. 50:1955;1096-1121.
19. Hayashi M., Sofuni T., Ishidate M. Jr. Kinetics of micronucleus formation in relation to chromosomal aberrations in mouse bone marrow. Mutat. Res. 127:1984;129-137.
20. MacGregor J.T., Wehr C.M., Gould D.H. Clastogen-induced micronuclei in peripheral blood erythrocytes: the basis of an improved micronucleus test. Environ. Mutagen. 2:1980;509-514.
21. MacGregor J.T., Wehr C.M., Henika P.R., Shelby M.D. The in vivo erythrocyte micronucleus test: measurement at steady state increases assay efficiency and permits integration with toxicity studies. Fund. Appl. Toxicol. 14:1990;513-522.
22. Tinwell H., Ashby J. Micronucleus morphology as a means to distinguish aneugens and clastogens in the mouse bone marrow micronucleus assay. Mutagenesis. 6:1991;193-198.