Assessment of a possible genotoxic environmental risk in sheep bred on grounds with strongly elevated contents of mercury, arsenic and antimony

Mutation Research - Genetic Toxicology

Volumn 368, Issue 3-4, 1996, Pages 267-274

  Gebel, Thomas ^a   Kevekordes, Sebastian ^a   Schaefer, Jasmin ^a   Von Platen, Hilmar ^b   Dunkelberg, Hartmut ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alkaline elution; Antimony; Arsenic; Biomonitoring; Mercury; Sister chromatid exchange

Indexed keywords

ANTIMONY; ARSENIC; MERCURY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BIOLOGICAL MONITORING; BLOOD ANALYSIS; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; NONHUMAN; PRIORITY JOURNAL; SHEEP; SISTER CHROMATID EXCHANGE; SOIL POLLUTION; WOOL;

EID: 0030570525     PISSN: 01651218     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(96)90068-3     Document Type: Article

References (24)

1. Boyum A. Separation of white blood cells. Nature. 204:1964;793.
2. 2 in cell culture systems. Chem. Biol. Interact. 49:1984;209-224.
3. Chittleborough G. A chemist's view of the analysis of human hair for trace elements. Sci. Total Environ. 14:1980;53-75.
4. Christie N.T., Cantoni O., Evans R.M., Meyn R.E., Costa M. Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. Biochem. Pharmacol. 33:1984;1661-1670.
5. DeFlora S., Bennicelli C., Bagnasco M. Genotoxicity of mercury compounds. A review. Mutation Res. 317:1994;57-79.
6. Dong J.-T., Luo X.-M. Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts. Mutation Res. 302:1993;97-102.
7. Dunkelberg H., Krames J. Sister-chromatid exchange in cultured lymphocytes of ewes and their newborn lambs. Mutation Res. 140:1984;117-121.
8. Friberg L., Vostal J. Mercury in the environment: An Epidemiological and Toxicological Appraisal. 1972;CRC Press, Cleveland.
9. Gebel T., Schaefer J., Beuermann I., Platen H.v., Dunkelberg H. Biomonitoring-Untersuchung bei Personen in Wohngebieten mit erhöhten Bodenwerten an Quecksilber, Arsen und Antimon. Forum Staedtehygiene. 45:1995;211-215.
10. Groth D.H., Stettler L.E., Burg J.R., Busey W.E., Grant G.C., Wong L. Carcinogenic effects of antimony trioxide and antimony ore concentrate in rats. J. Toxicol. Environ. Health. 18:1986;607-626.
11. Hengstler J.G., Fuchs J., Gebhard S., Oesch F. Glycoaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity. Mutation Res. 304:1994;229-334.
12. Hermann M., Schweinsberg F. Biomonitoring and evaluation of mercury burden from amalgam fillings - Mercury analysis in urine without and after oral gavagof 2,3-dimercapto-1 propane sulfonic acid (DMPS) and in hair. Zbl. Hygiene. 194:1993;271-291.
13. Jones R.D. Survey of antimony workers: mortality 1961-1992. Occup. Environ. Med. 51:1994;772-776.
14. Kentner M., Leinemann M., Schaller K.-H., Weltle D., Lehnert G. External and internal antimony exposure in starter battery production. Int. Arch. Occup. Environ. Health. 67:1995;119-123.
15. Kohn K.W., Ewig R.A.G., Erickson L.C., Zwelling L.A. Measurement of strand breaks and cross-links by alkaline elution. Friedberg E.C., Hanawalt P.C. DNA Repair. 1980;379-401 Dekker, New York.
16. Kuroda K., Endo G., Okamoto A., Yoo Y.S., Horiguchi S. Genotoxicity of beryllium, gallium and antimony in short-term assays. Mutation Res. 264:1991;163-170.
17. Lee C.-T., Oshimura M., Barett J.C. Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenic effects in Syrian hamster embryo cells in culture. Carcinogenesis. 6:(10):1985;1421-1426.
18. Lerda D. Sister-chromatid exchange (SCE) among individuals chronically exposed to arsenic in drinking water. Mutation Res. 312:1994;111-120.
19. Morimoto K., Iijima S., Koizumi A. Selenite prevents the induction of sister-chromatid exchanges by methyl mercury and mercuric chloride in human whole-blood cultures. Mutation Res. 102:1982;183-192.
20. Perry P., Wolff S. New Giemsa method for differential staining of sister chromatid exchanges. Nature. 251:1974;156-158.
21. Sina J.F., Bean C.L., Dysart G.R., Taylor V.I., Bradley M.O. Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential. Mutation Res. 113:1983;357-391.
22. Sterzel W., Bedford P., Eisenbrand G. Automated determination of DNA using the fluorochrome Hoechst 33258. Anal. Biochem. 147:1985;462-467.
23. 74As. Anal. Biochem. 86:1978;505-511.
24. Yamoto N. Concentration and chemical species of arsenic in human urine and hair. Bull. Environ. Contam. Toxicol. 40:1988;633-640.