Synthesis of 15-deoxy-12-hydroxy-10-(trifluoromethyl)-Δ7-PGA1 methyl ester

Journal of Organic Chemistry

Volumn 63, Issue 17, 1998, Pages 5971-5976

  Tius, Marcus A ^a   Hu, Huaping ^a   Kawakami, Joel K ^a   Busch Petersen, Jakob ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY 12 HYDROXY 10 (TRIFLUOROMETHYL) DELTA7 PROSTAGLANDIN A1; PROSTAGLANDIN DERIVATIVE; PROSTANOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYCLIZATION; CYTOSTASIS; CYTOTOXICITY; HUMAN; HUMAN CELL; ISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 0032555424     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980621z     Document Type: Article

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30. This material is extremely sensitive even to weak aqueous acids or bases. Solvent evaporation was done using a silanized glass flask.