The relationship between plasma insulin level, prostaglandin production by adipose tissue, and blood pressure in normal rats and rats with diabetes mellitus and diabetic ketoacidosis

Metabolism: Clinical and Experimental

Volumn 45, Issue 6, 1996, Pages 691-698

  Chatzipanteli, Katina ^b   Head, Caroline ^b   Megerman, Joseph ^b   Axelrod, Lloyd ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; GLUCOSE; INSULIN; PROSTAGLANDIN E2;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CALCULATION; CELL POPULATION; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; LIPOLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; STATISTICAL ANALYSIS; STREPTOZOCIN DIABETES;

EID: 0029977059     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(96)90133-X     Document Type: Article

References (30)

1. Axelrod L: Insulin, prostaglandins and the pathogenesis of hypertension. Diabetes 40:1223-1227, 1991
2. Axelrod L, Levine L: Inhibitory effect of insulin on prostacyclin production by isolated rat adipocytes. Prostaglandins 25:571-579, 1983
3. Axelrod L, Ryan CA, Shaw JL, et al: Prostacyclin production by isolated rat adipocytes: Evidence for cyclic adenosine 3′,5′-monophosphate-dependent and -independent mechanisms and for a selective effect of insulin. Endocrinology 119:2233-2239, 1986
4. Axelrod L, Levine L: Plasma prostaglandin levels in rats with diabetes mellitus and diabetic ketoacidosis. Diabetes 31:994-1001, 1982
5. 2 in patients with diabetic ketoacidosis and in normal fasting subjects. Diabetes 35:1004-1010, 1986
6. 2 and prostacyclin in rat adipose tissue. Diabetes 41:927-935, 1992
7. Pfeffer JM, Pfeffer MA, Frolich ED: Validity of an indirect tailcuff method for determining systolic arterial pressure in unanesthetized normotensive and spontaneously hypertensive rats. J Lab Clin Med 78:957-961, 1971
8. Williamson DH, Mellanby J, Krebs HA: Enzymic determination of D-β-hydroxybutyric acid and acetoacetic acid in blood. Biochem J 82:90-98, 1962
9. Albino JDM, Ekins RP, Maritz G, et al: A sensitive precise RIA of serum insulin relying on charcoal separation of bound and free hormone moieties. Acta Endocrinol (Copenh) 70:487-509, 1972
10. 2 production by rat adipose tissue. Diabetes 38:1123-1132, 1989
11. Hirsch J, Gallian E: Methods for the determination of adipose cell size in man and animals. J Lipid Res 9:110-119, 1968
12. Marcus C, Karpe B, Bolme P, et al: Changes in catecholamine-induced lipolysis in isolated human fat cells during the first year of life. J Clin Invest 79:1812-1818, 1987
13. Zinder O, Shapiro B: Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells. J Lipid Res 12:91-95, 1971
14. 125I) RIA Kit. Instructions and Material Safety Data Handbook. Cambridge, MA, Advanced Magnetics Inc, 1992
15. Modan M, Halkin H, Almog S, et al: Hyperinsulinemia: A link between hypertension, obesity and glucose intolerance. J Clin Invest 75:809-817, 1985
16. Manicardi V, Camellini L, Bellodi G, et al: Evidence for an association of high blood pressure and hyperinsulinemia in obese man. J Clin Endocrinol Metab 62:1302-1304, 1986
17. Fournier AM, Gadia MT, Kubrusly DB, et al: Blood pressure, insulin, and glycemia in non-diabetic subjects. Am J Med 80:861-864, 1986
18. Bauman W, Maimen M, Langer O: An association between hyperinsulinemia and hypertension during the third trimester of pregnancy. Am J Obstet Gynecol 159:446-450, 1988
19. Brown ML, Jakubowski JA, Leventis LL, et al: Elevated glucose alters eicosanoid release from porcine aortic endothelial cells. J Clin Invest 82:2136-2141, 1988
20. Brown ML, Clark CA, Vaillancourt R, et al: Elevated glucose alters A23187-induced release of arachidonic acid from porcine aortic endothelial cells by enhancing reacylation. Biochim Biophys Acta 1165:239-247, 1992
21. Tesfamarian B, Cohen RA: Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol 263:H321-H326, 1992
22. Williams B, Schrier RW: Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells. J Clin Invest 92:2889-2896, 1993
23. Quyyumi A, Iaffaldano R, Guerrero JL, et al: Prostacyclin and pathogenesis of hemodynamic abnormalities of diabetic ketoacidosis in rats. Diabetes 38:1585-1594, 1989
24. Larsen OA, Lassen NA, Quaade F: Blood flow through human adipose tissue determined with radioactive xenon. Acta Physiol Scand 66:337-345, 1966
25. West DB, Prinz WA, Francendese AA, et al: Adipocyte blood flow is decreased in obese Zucker rats. Am J Physiol 253:R228-R233, 1987
26. Prinz WA, West DB, Cohen A, et al: Intraarterial insulin infusion reduces adipose tissue blood flow (ATBF). Fed Proc 45:601, 1986 (abstr)
27. West DB, Prinz WA, Greenwood MRC: Regional changes in adipose tissue blood flow and metabolism in rats after a meal. Am J Physiol 257:R711-R716, 1989
28. Madsen J, Malchow-Moller A: Effects of glucose, insulin and nicotinic acid on adipose tissue blood flow in rats. Acta Physiol Scand 118:175-180, 1983
29. Zorzano A, Balon TW, Jakubowski JA, et al: Effects of insulin and prior exercise on prostaglandin release from perfused rat muscle. Biochem J 240:437-443, 1986
30. Anderson EA, Hoffman RP, Balon TW, et al: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87:2246-2252, 1991