Solid phase synthesis of phosphinopeptoids as transition state analog inhibitors

Tetrahedron Letters

Volumn 39, Issue 21, 1998, Pages 3375-3378

  Dorff, Peter H ^a   Chiu, Gordon ^a   Goldstein, Steven W ^a   Morgan, Bradley P ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHINOPEPTOID; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG SYNTHESIS; HYDROLYSIS; SOLID PHASE EXTRACTION;

EID: 0032555017     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00496-1     Document Type: Article

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26. 3CN to determine accurate yields of 7a-d with > 95% purity.
27. The yields for 1a-d were 90, 48, 40, and 17% respectively.
28. 3CN to determine accurate yields of 7e-g with > 95% purity.