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Volumn 8, Issue 20, 1998, Pages 2913-2918

First synthesis of alternating sate-phosphotriester/phosphodiester prooligonucleotides on solid support

Author keywords

[No Author keywords available]

Indexed keywords

ESTERASE; OLIGONUCLEOTIDE; PRODRUG;

EID: 0032552844     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00518-6     Document Type: Article
Times cited : (19)

References (15)
  • 10
    • 0010397494 scopus 로고    scopus 로고
    • note
    • 10. MS ESI (neg. mode): 7 mass calc. 4630.2 found 4630.7; 8 mass calc. 4629.2 found 4629.7; 9 mass calc. 4725.6 found 4724.9; 10 mass calc. 4532.8 found 4533.7; 11 mass calc. 4522.0 found 4522.0; 12 mass calc. 4628.8 found 4629.5. Noteworthy that the monophosphorothioate at 3'-end of 7 and 9 was slightly desulfurized during the photolysis (7 -S mass calc. 4613.1 found 4613.5 and 9 -S mass calc. 4709.5 found 4708.9). Presence of dithiothreitol avoids this side reaction.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.