Shared antigenic epitopes on the V3 loop of HIV-1 gp120 and proteins on activated human T cells

Virology

Volumn 246, Issue 1, 1998, Pages 53-62

  Trujillo, J Roberto ^a   Rogers, Rick A ^a   Brain, Joseph D ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CELL PROTEIN; EPITOPE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PHYTOHEMAGGLUTININ; RECOMBINANT PROTEIN; VIRUS ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032551186     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9185     Document Type: Article

References (38)

1. Banda, N. K., Bernier, J., Kurahara, D. K., Kurrle, R., Haigwood, N., Sekaly, R. P., and Finkel, T. H. (1992). Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J. Exp. Med. 176, 1099-1106.
2. Barin, F., M'Boup, S., Denis, F., Kanki, P., Allan, J. S., Lee, T. H., and Essex, M. (1985). Serological evidence for virus related to simian T-lymphotropic retrovirus III in residents of West Africa. Lancet II, 1387-1390.
3. H3 gene products: Natural ligands for HIV gp120. Science 261, 1588-1591.
4. Boucher, C. A., de Wolf, F., Houweling, J. T., Bakker M., Dekker, J., Roos, M. T., Coutinho, R. A., van der Noordaa, J., and Goudsmit, J. (1989). Antibody response to a synthetic peptide covering a LAV-1/HTLV-IIIB neutralization epitope and disease progression. AIDS 3, 71-76.
5. Centers for Disease Control. (1992). 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 41, 1-19.
6. Duerst, R. E., Rose, D., and Frantz, C. N. (1991). Complement depletion in vitro limits monoclonal antibody 6-19-dependent complement-mediated killing of tumor cells in bone marrow. Exp. Hematol. 19, 863-867.
7. Emini, E. A., Schleif, W. A., Nunberg, J. H., Conley, A. J., Eda, Y., Tokiyoshi, S., Putney, S. D., Matsushita, S., Cobb, K. E., Jett, C. M., Eichberg, J. W., and Murphy, K. K. (1992). Prevention of HIV-1 infection in chimpanzees by gp120 V3 domain-specific monoclonal antibody. Nature 355, 728-730.
8. Fauci, A. S. (1993). Multifactorial nature of human immunodeficiency virus disease: Implications for therapy. Science 262, 1011-1018.
9. Foley, B., and Korber, B. (1995). In "Human Retroviruses and AIDS 1995" (G. Myers, B. H. Hahn, J. W. Mellors, L. E. Henderson, B. Korber, K. T. Jeang, F. E. McCutchan, and G. N. Pavlakis, Eds.), pp. III77-150. Los Alamos National Laboratory, Los Alamos, New Mexico.
10. Freed, E. O., Myers, D. S., and Risser, R. (1992). Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain. J. Virol. 65, 190-194.
11. Fujinami, R. S., and Oldstone, M. B. A. (1985). Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity. Science 230, 1043-1045.
12. Fujinami, R. S., and Oldstone, M. B. A. (1989). Molecular mimicry as a mechanism for virus-induced autoimmunity. Immunol. Res. 8, 3-15.
13. Gougeon, M. L., and Montagnier, L. (1993). Apoptosis in AIDS. Science 260, 1269-1270.
14. Hinkula, J., Bratt, G., Gilljam, G., Nordlund, S., Broliden, P. A., Holmberg, V., Olausson-Hansson, E., Albert, J., Sandstrom, E., Wahren, B. (1994). Immunological and virological interactions in patients receiving passive immunotherapy with HIV-1 neutralizing monoclonal antibodies. J. AIDS7, 940-951.
15. Ho, D. D., Neumann, A. U., Perelson, A. S., Chen, W., Leonard, J. M., and Makowitz, M. (1995). Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123-126.
16. Javaherian, K., Langlois, A. J., LaRosa, G. J., Profy, A. T., Bolognesi, D. P., Herlihy, W. C., Putney, S. D., and Matthews, T. J. (1990). Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1. Science 250, 1590-1593.
17. Koenig, S., Earl, P., Powell, D., Pantaleo, G., Merli, S., Moss, B., and Fauci, A. S. (1988). Group-specific, MHC class I restricted cytotoxic responses to HIV-1 envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual. Proc. Natl. Acad. Sci. USA 85, 8638-8642.
18. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
19. LaRosa, G. L., Davide, J. P., Weinhold, K., Waterbury, J. A., Profy, A. Y., Lewis, J. A., Langlois, A. J., Dreesman, G. R., Boswell, R. N., and Shadduck, P. (190). Conserved sequences and structural elements in the HIV-1 principal neutralizing determinant. Science 249, 932-935.
20. Levy, J. A. (1994). "HIV-1 and the Pathogenesis of AIDS," 3rd ed., pp. 174-180. Am. Soc. for Microbiol. Washington, DC.
21. Li, J. C., Friedman, D. J., Wang, C., Metelev, V., and Pardee, A. B. (1995). Induction of apoptosis in uninfected lymphocytes by HIV-1 tat protein. Science 268, 429-431.
22. Mellors, J. W., Rinaldo, C. R., Gupta, P., White, R. M., Todd, J. A., and Kingsley, L. A. (1996). Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 272, 1167-1170.
23. + lymphocyte counts and the risk of progression to AIDS. N. Engl. J. Med. 334, 426-431.
24. Robey, W. G., Safari, B., Oroszlan, S., Arthur, L. O., Gonda, M. A., Gallo, R. C., and Fishinger, P. J. (1985). Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients. Science 228, 593-595.
25. Silvestris, F., Williams, R. C., and Dammacco, F. (1995). Autoreactivity in HIV-1 infection: The role of molecular mimicry. Clin. Immunol. Immunopathol. 75, 197-205.
26. Skinner, M. A., Langlois, A. J., McDanal, C. B., McDougal, J. S., Bolognesi, D. P., and Matthews, T. J. (1988). Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4. J. Virol. 62, 4195-4200.
27. Srinivasappa, J., Saegusa, J., Prabhakar, B. S., Gentry, M. K., Buchmeier, M. L., Wiktor, T. J., Koprowski, H., Oldstone, M. B. A., and Notkins, A. L. (1986). Molecular mimicry: Frequency of reactivity of monoclonal antiviral antibodies with normal tissues. J. Virol. 57, 397-401.
28. + T cells. Nature 327, 710-713.
29. Takahashi, H., Nakagawa, Y., Pendleton, C. D., Houghten, R. A., Yokomuro, K., Germain, R. N., and Berzofsky, J. A. (1992). Induction of broadly cross-reactive cytotoxic t cells recognizing an HIV-1 envelope determinant. Science 255, 333-336.
30. Trujillo, J. R., McLane, M. F., DelaMonte, S., Navia, B., Brain, J. D., and Essex, M. (1996a). Molecular mimicry in HIV-1 neuropathogenesis: Human antibodies that bind to gp120 V3 loop and human brain proteins. J. Neurovirol. 2, 21.
31. 3 loop as a determinant of a CD4-negative neuronal cell tropism for HIV-1. Virology 217, 613-617.
32. Trujillo, J. R., McLane, M. F., Lee, T. H., and Essex, M. (1993). Molecular mimicry between the human immunodeficiency virus type 1 gp120 V3 loop and human brain proteins. J. Virol. 67, 7711-7715.
33. Wang, X. Z. S., Rushlow, K. E., Issel, C. J., Cook, R. R., Raabe, M. L., Chong, Y. H., Costa, L., and Montelaro, R. C. (1994). Enhancement of EIAV replication and disease by immunization with a baculovirus-expressed recombinant envelope surface glycoprotein. Virology 199, 247-251.
34. Wei, X., Ghosh, S. K., Taylor, M. E., Johnson, V. A., Emini, E. A., Deutsch, P., Lifson, J. D., Bonhoeffer, S., Novak, M. A., Hahn, B. H., Saag, M. S., and Shaw, G. M. (1995). Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373, 117-122.
35. Weiss, R. A., Clapham, P. R., Cheingsong-Popov, R., Dalgleish, A. G., Carne, C. A., Weller, I. V., and Tedder, R. S. (1985). Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients. Nature 316, 69-72.
36. Westendorp, M. O., Frank, R., Ochsenbauer, C., Striker, K., Dhein, J., Walczak, H., Debatin, K. M., and Krammer, P. H. (1995). Sensitization of T cells to CD95-mediated apoptosis by HIV-1 tat and gp120. Nature 375, 497-500.
37. + T cells by non-syncytium-inducing macrophage-tropic human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 91, 10237-10241.
38. Zack, J. A. (1995). "Cell Activation and Apoptosis in HIV Infection" (J. M. Andrieu and W. Lu, Eds.) Chap. 3, Vol. 374. Plenum, New York.