Macrocyclic inhibitors of penicillopepsin. 2. X-ray crystallographic analyses of penicillopepsin complexed with a P3-P1 macrocyclic peptidyl inhibitor and with its two acyclic analogues

Journal of the American Chemical Society

Volumn 120, Issue 19, 1998, Pages 4610-4621

  Ding, Jinhui ^a   Fraser, Marie E ^a   Meyer, J Hoyt ^b   Bartlett, Paul A ^b   James, Michael N G ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE DERIVATIVE; ASPARTIC PROTEINASE; ATROLACTIC ACID; ENZYME INHIBITOR; LEUCINE; MACROCYCLIC COMPOUND; PEPSIN A; PHOSPHONIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; MOLECULAR MIMICRY; X RAY CRYSTALLOGRAPHY;

EID: 0032550656     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja973714r     Document Type: Article

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