Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides

FEBS Letters

Volumn 425, Issue 1, 1998, Pages 91-96

  Abe, Takayuki ^a   Takai, Kazuyuki ^a   Nakada, Susumu ^b   Yokota, Tomoyuki ^c   Takaku, Hiroshi ^a  

^a CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

^c Rational Drug Design Laboratories   (Japan)

Author keywords

Antisense phosphodiester oligonucleotide; CAT assay; Circular dumbbell RNA DNA chimeric oligonucleotide; Exonuclease resistance; Influenza virus; Melting temperature; Nucleoprotein; RNA polymerase; RNase H

Indexed keywords

COMPLEMENTARY DNA; NUCLEOPROTEIN; RNA POLYMERASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA RNA HYBRIDIZATION; DNA STRUCTURE; ENZYME INHIBITION; GENE EXPRESSION REGULATION; IN VITRO STUDY; INFLUENZA VIRUS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; RNA STRUCTURE;

DNA; DNA-DIRECTED RNA POLYMERASES; GENE EXPRESSION REGULATION; NUCLEIC ACID HYBRIDIZATION; NUCLEOPROTEINS; OLIGONUCLEOTIDES, ANTISENSE; ORTHOMYXOVIRIDAE; RIBONUCLEASE H, CALF THYMUS; RNA;

ANIMALIA; INFLUENZA VIRUS; INFLUENZAVIRUS A; RNA VIRUSES;

EID: 0032549657     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)00206-3     Document Type: Article

References (34)

1. Stanley, T.C. (Ed.) (1995) Therapeutic Applications of Oligonucleotides, R.G. Landes Company, Austin, TX.
2. Sudhir, A. (Ed.) (1996) Antisense Therapeutics, Humana Press, Totowa, NJ.
3. Paul, S.M. (1996) in: Nucleic Acid Research and Molecular Biology: Development of Antisense and Antigene Oligonucleotide Analogs (Waldo, E.C. and Kivie, M., Eds.), pp. 261-291, Academic Press, San Diego, CA.
4. Reimar, S. and Wolfgang, B. (Eds.) (1997) Antisense - From Technology to Therapy, Blackwell Science, Vienna.
5. Zamecnik P.C., Goodchild J., Taguchi Y., Sarin P.S. Proc. Natl. Acad. Sci. USA. 83:1986;4143-4146.
6. Goodchild J., Agrawal S., Civera M.P., Sarin P.S., Sun D., Zamecnik P.C. Proc. Natl. Acad. Sci. USA. 85:1988;5507-5511.
7. Wickstrom E. J. Biochem. Biophys. Methods. 13:1987;97-102.
8. Shaw J., Kent K., Bird J., Fishback J., Froehler B. Nucleic Acids Res. 19:1991;747-750.
9. Stein C.A., Cohen J.S. Cancer Res. 48:1988;2559-2668.
10. Uhlmann E., Peyman A. Chem. Rev. 90:1990;544-584.
11. Matsukura M., Shinozuka K., Zon G., Mitsuya H., Reitz M., Cohen J.C., Broder S. Proc. Natl. Acad. Sci. USA. 84:1987;7706-7710.
12. Majumdar C., Stein C.A., Cohen J.S., Broder S., Wilson S.H. Biochemistry. 28:1989;1340-1346.
13. Maury G., Elalaoui A., Morvan F., Müller B., Imbach J.-L., Goody R.S. Biochem. Biophys. Res. Commun. 186:1992;1249-1256.
14. Stein C.A., Neckers L.M., Nair B.C., Mumbauer S., Hoke G., Pal R. J. Acquir. Immune Defic. Syndr. 4:1991;686-693.
15. Lederman S., Sullivan G., Benimetskaya L., Lowy I., Land K., Khaled Z., Cleary A., Yakubov L., Stein C.A. Antisense Res. Dev. 6:1996;281-289.
16. Gamper H.B., Reed M.W., Cox T., Virosco J.S., Adams A.D., Gall A.A., Scholler J.K., Meyer R.B. Jr. Nucleic Acids Res. 21:1993;145-150.
17. Rumney S.I.V., Kool E.T. Angew. Chem. 104:1992;1686-1689.
18. Shaw J.P., Kent K., Bird J., Fishbach J., Froehler B. Nucleic Acids Res. 19:1991;747-750.
19. Prakash, G. and Kool, E.T. (1991) J. Chem. Soc. Chem. Commun. 1161-1163.
20. Clusel C., Ugarte E., Enjolras N., Vasseur M., Blumenfled M. Nucleic Acids Res. 21:1993;3405-3411.
21. Kool E.T. Annu. Rev. Biophys. Biomol. Struct. 25:1996;1-28.
22. Khan I.M., Coulson J.M. Nucleic Acids Res. 21:1993;2957-2958.
23. Poddevin B., Meguenni S., Elias I., Vasseur M., Blumenfeld M. Antisense Res. Rev. 4:1994;147-154.
24. Chu B.C., Orgel L.E. Nucleic Acids Res. 19:1991;6958.
25. Lim C.L., Hunt C.A. Nucleosides Nucleotides. 16:1997;41-51.
26. Nakamura Y., Oda K., Nakada S. J. Biochem. 110:1991;395-401.
27. Kimura N., Nishida M., Nagata K., Ishihama A., Oda K., Nakada S. J. Gen. Virol. 73:1992;1321-1328.
28. Yamanaka K., Ogasawara N., Yoshikawa H., Ishihama A., Nagata K. Proc. Natl. Acad. Sci. USA. 88:1991;5369-5373.
29. Yakubov L.A., Deeva E.A., Zarytova V.F., Ivanova E.M., Ryte A.S., Yurchenko L.V., Vlassov V.V. Proc. Natl. Acad. Sci. USA. 86:1989;6454-6458.
30. Loke S.L., Stein C.A., Zhang X.H., Mori K., Nakanishi M., Subasinghe C., Cohen J.S., Neckers L.M. Proc. Natl. Acad. Sci. USA. 86:1989;3474-3478.
31. Noe C., Hernandez-Borrel J., Kinsky S.C., Matsuura E., Leserman L. Biochim. Biophys. Acta. 946:1988;253-260.
32. Akhtar, S. (Ed.) (1995) Delivery Strategies for Antisense Oligonucleotide Therapeutics, CRC Press, New York.
33. Hatta T., Nakagawa Y., Takaki K., Nakada S., Yokoto T., Takaku H. Biochem. Biophys. Res. Commun. 233:1996;341-346.
34. Leiter J.M.E., Agrawal S., Palese P., Zamecnik P.C. Proc. Natl. Acad. Sci. USA. 87:1990;3430-3434.