Decreased hepatobiliary secretion of inorganic mercury, its deposition and toxicity in the Eisai hyperbilirubinemic rat with no hepatic canalicular organic anion transporter

Toxicology

Volumn 126, Issue 1, 1998, Pages 23-31

  Sugawara, Naoki ^a   Lai, Yu Rong ^a   Sugaware, Chieko ^a   Arizono, Koji ^b  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Biliary excretion of inorganic Hg and glutathione; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter; Eisai hyperbilirubinemic rats; Glutathione S conjugate export pump; Hepatic and renal lesions

Indexed keywords

ADENOSINE TRIPHOSPHATE; BILIRUBIN; CARRIER PROTEIN; GLUTATHIONE; MERCURIC CHLORIDE; MERCURY; MERCURY 203; METALLOTHIONEIN; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; HYPERBILIRUBINEMIA; INTRAHEPATIC BILE DUCT; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRAIN DIFFERENCE;

ANIMALS; ANION TRANSPORT PROTEINS; BILE CANALICULI; BIOLOGICAL AVAILABILITY; CARRIER PROTEINS; HYPERBILIRUBINEMIA; KIDNEY; LIVER; MALE; MERCURIC CHLORIDE; METALLOTHIONEIN; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0032548957     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)00170-4     Document Type: Article

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