Solution-phase parallel synthesis of benzoxazines using a polymer-supported carbodiimide

Tetrahedron Letters

Volumn 39, Issue 12, 1998, Pages 1487-1488

  Buckman, Brad O ^a   Morrissey, Michael M ^a   Mohan, Raju ^a  

^a BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; BENZOXAZINE DERIVATIVE; CYANAMIDE; ISOCYANIC ACID DERIVATIVE;

ARTICLE; CYCLIZATION; SYNTHESIS;

EID: 0032546239     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00012-4     Document Type: Article

References (13)

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3. (c) Gordon, E. M.; Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A. J. Med. Chem. 1994, 37, 1385.
4. 2. (a) Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Tetrahedron Lett. 1996, 37, 7193-7196.
5. (b) Gayo, L. M.; Suto, M. J. Tetrahedron Lett. 1997, 38, 513-516.
6. (c) Siegel, M, G.; Hahn, P. J.; Dressman, B. A.; Fritz, J. E.; Grunwell, J. R.; Kaldor, S. W. Tetrahedron Lett. 1997, 19, 3357-3360.
7. (d) Thomas, J. B.; Fall, M. J.; Cooper, J. B.; Burgess, J. P.; Carroll, F. I., Tetrahedron Lett. 1997, 38, 5099-5102.
8. 3. Buckman, B. O.; Mohan, R. Tetrahedron Lett. 1996, 26, 4439-4442.
9. 4. (a) Krantz, A.; Spencer, R. W.; Tam, T. F.; Liak, T. J.; Copp, L. J.; Thomas, E. M.; Rafferty, S. P. J. Med. Chem. 1990, 33, 464-479.
10. (b) Abood, N. A.; Schretzman, L. A.; Flynn, D. L.; Houseman, K. A.; Wittwer, A. J.; Dilworth, V. M.; Hippenmeyer, P. J.; Holwerda, B. C. Bioorg. Med. Chem. Lett. 1997, 16, 2105-2108.
11. (c) Jarvest, R. L.; Parratt, M. J.; Debouck, C. M.; Gorniak, J. G.; Jennings, L. J.; Serafinowska, H. T.; Strickler, J. E. Bioorg. Med. Chem. Lett. 1996, 20, 2463-2466.
12. 5. Desai, M. C.; Stephens Stramiello, L. M. Tetrahedron Lett. 1993, 48, 7685-7688.
13. 6) 3.75 (s, 3), 6.95 (d, 2, J = 4, 7.20-7.40 (m, 2), 7.65 (d, 1, J = 4), 7.75 (dd, 1, J = 4,4), 7.95 (d, 1, J = 4). MS (m/z) 268.