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d) For a force-field model for intramolecular radical additions, see: Spellmeyer, D. C.; Houk, K. N. J. Org. Chem. 1987, 52, 959.
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e) For stereoselectivity in 6-heptenyl radical cyclizations, see: Hanessian S.; Dhanoa, D. S.; Beaulieu, P. L. Can. J. Chem. 1987, 65, 1859.
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40
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0010702627
-
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note
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9.-For instance, the cyclization of 4-methylhexenyl radical gives a 83:17 ratio of trans: cis isomers (see ref. 8c,d).
-
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41
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0000729872
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10.-a) Gung, B. W.; Melnick, J. P.; Wolf, M. A.; Marshall, J. A.; Beaudoin, S. J. Org. Chem. 1994, 59, 5609.
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47
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0010701195
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note
-
3 (in ppm) for compounds 5-8 and 13: cis-5b= 4.32, trans-5b= 3.85; cis-5c= 4.01, trans-5c= 3.66; cis-6a= 4.10, trans-6a= 3.25; cis-6b= 3.91, trans-6b= 3.39; cw-7a= 4.68, trans-7a= 4.25; cis-7b= 4.55, trans-7b= 4.23; cis-8a= 4.67, trans-8a= 4.15; cis-8b= 4.66, trans-8b= 4.45; cis-13= 4.05, trans-13= 3.75.
-
-
-
-
48
-
-
0010698527
-
-
note
-
3 (in ppm) for compounds 5-8: cis-5b= 43.1, trans-5b= 56.5; cis-5c= 56.5, trans-5c= 59.8; ciy-6a= 57.9, trans-6a= 59.1; cis-6b= 55.2, trans-6b= 58.4; cis-6c= 57.5, trans-6c= 58.3; cis-7a= 55.2, trans-7a= 60.5; cis-7b= 54.4, trans-7b= 59.3; cis-8a= 55.8, trans-8a= 61.1.
-
-
-
-
49
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0000721036
-
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15.-For some recent reviews on cascade cyclizations, see: a) Malacria, M. Chem. Rev. 1996, 96, 289.
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Malacria, M.1
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0010656674
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See also ref. 1
-
d) See also ref. 1.
-
-
-
-
53
-
-
0010659982
-
-
note
-
C=C trans= 11.7-12.6 Hz).
-
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-
-
54
-
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0001292302
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17.-Snider, B. B.; Kirk, T. C.; Roush, D. M.; Gonzalez, D. J. Org. Chem. 1980, 45, 5015.
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