-
1
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signaling
-
(a) Zhow, S.; Carraway, K. L.; Eck, M. J.; Cantley, L. C. Catalytic specificity of protein-tyrosine kinases is critical for selective signaling. Nature 1995, 373, 536-539.
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Zhow, S.1
Carraway, K.L.2
Eck, M.J.3
Cantley, L.C.4
-
3
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
(c) Davis, R. J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 1993, 268, 14553-14556.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14553-14556
-
-
Davis, R.J.1
-
4
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
(d) Zhow, S.; Shoelson, S. E.; Chauduri, M.; Pawson, T.; Fajardo, J. E. SH2 domains recognize specific phosphopeptide sequences. Cell 1993, 72, 767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Zhow, S.1
Shoelson, S.E.2
Chauduri, M.3
Pawson, T.4
Fajardo, J.E.5
-
5
-
-
0026674221
-
Characterization of protein tyrosine kinases from human breast cancer involvement of the c-Src oncogene product
-
Ottenhoff-Kalf, A. E.; Rijksen, G.; Van Beurden, E. A.; Steal, G. E. Characterization of protein tyrosine kinases from human breast cancer. involvement of the c-Src oncogene product. Cancer Res. 1992, 52, 4773-4778.
-
(1992)
Cancer Res.
, vol.52
, pp. 4773-4778
-
-
Ottenhoff-Kalf, A.E.1
Rijksen, G.2
Van Beurden, E.A.3
Steal, G.E.4
-
6
-
-
0028000069
-
Signal transduction theraphy- A novel approach to disease managment
-
Levitzki, A. Signal transduction theraphy- A novel approach to disease managment. Eur. J. Biochem. 1994, 226, 1-13.
-
(1994)
Eur. J. Biochem.
, vol.226
, pp. 1-13
-
-
Levitzki, A.1
-
7
-
-
0028173679
-
Myristylation and palmitylation of Src family members: The fats of the matter
-
(a) Resh, M. D. Myristylation and palmitylation of Src family members: the fats of the matter. Cell 1994, 76, 411-413.
-
(1994)
Cell
, vol.76
, pp. 411-413
-
-
Resh, M.D.1
-
8
-
-
0027300619
-
The when and how of Src regulation
-
(b) Howell, J. A. The when and how of Src regulation. Cell 1993, 73, 1051-1054.
-
(1993)
Cell
, vol.73
, pp. 1051-1054
-
-
Howell, J.A.1
-
9
-
-
0031025991
-
Three-dimensional structure of tyrosine kinase c-Src
-
Xu, W.; Harrison, S. C.; Eck, M. J. Three-dimensional structure of tyrosine kinase c-Src. Nature 1997, 385, 595-601.
-
(1997)
Nature
, vol.385
, pp. 595-601
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
10
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
Van Der Geer, P.; Hunter, T.; Lindberg, R. A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell. Biol. 1994, 10, 251-337.
-
(1994)
Annu. Rev. Cell. Biol.
, vol.10
, pp. 251-337
-
-
Van Der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
11
-
-
0026316096
-
Growth factors and cancer
-
(a) Aaronson, S. A. Growth factors and cancer. Science 1991, 254, 1146-1153.
-
(1991)
Science
, vol.254
, pp. 1146-1153
-
-
Aaronson, S.A.1
-
12
-
-
0026069474
-
-
(b) Cantley, L. C.; Auger, K. R.; Carbenter, C.; Graziani, A.; Soltoff, S. Oncogenes and signal transduction. Cell 1991, 64, 281-302.
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carbenter, C.3
Graziani, A.4
Oncogenes, S.S.5
Transduction, S.6
-
13
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
(c) Ullrich, A.; Schlessinger, J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990, 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
14
-
-
0025015390
-
Oncogenes evoke new cancer therapies
-
Marx, J. Oncogenes evoke new cancer therapies. Science 1990, 249, 1376-1378.
-
(1990)
Science
, vol.249
, pp. 1376-1378
-
-
Marx, J.1
-
15
-
-
0028968949
-
Tyrosine Kinase inhibition: An Approach to Drug Development
-
(a) Levitzki, A.; Gazit, A. Tyrosine Kinase inhibition: An Approach to Drug Development. Science 1995, 267, 1782-1788.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
16
-
-
0028950061
-
Inhibition of cell signaling pathways
-
(b) Langdon, S. P.; Smith, G. F. inhibition of cell signaling pathways. Cancer Treat. Rev. 1995, 21, 65-89.
-
(1995)
Cancer Treat. Rev.
, vol.21
, pp. 65-89
-
-
Langdon, S.P.1
Smith, G.F.2
-
17
-
-
0024554077
-
Overexpression of transforming growth factor α in psoriatic epidermis
-
Elder, J. E.; Fisher, G. J.; Lindquist, P. B.; Voorthees, J. J.; Coffey, R. J., Jr. Overexpression of transforming growth factor α in psoriatic epidermis. Science 1989, 243, 811-814.
-
(1989)
Science
, vol.243
, pp. 811-814
-
-
Elder, J.E.1
Fisher, G.J.2
Lindquist, P.B.3
Voorthees, J.J.4
Coffey Jr., R.J.5
-
18
-
-
0026673511
-
Signal transduction in athero-sclerosis: Integration of cytokines and the eicosanoidnetwork
-
Hajjar, D. P.; Pomerants, H. B. Signal transduction in athero-sclerosis: integration of cytokines and the eicosanoidnetwork. FASEB J. 1992, 6, 2933-2941.
-
(1992)
FASEB J
, vol.6
, pp. 2933-2941
-
-
Hajjar, D.P.1
Pomerants, H.B.2
-
19
-
-
0026451516
-
A cascade model for restenosis as special case of atherosclerosis progression
-
Libby, P.; Schwartz, D.; Borgie, E.; Tanaka, H. A cascade model for restenosis as special case of atherosclerosis progression. Circulation 1992, 86, 47-52.
-
(1992)
Circulation
, vol.86
, pp. 47-52
-
-
Libby, P.1
Schwartz, D.2
Borgie, E.3
Tanaka, H.4
-
20
-
-
27644447540
-
Recent advances in tyrosine kinase inhibitors
-
(a) Fry, W. D. Recent advances in tyrosine kinase inhibitors. Annu. Rep. Med. Chem. 1996, 31, 151-160.
-
(1996)
Annu. Rep. Med. Chem.
, vol.31
, pp. 151-160
-
-
Fry, W.D.1
-
21
-
-
0028172837
-
Tyrosine protein kinase inhibition and cancer
-
(b) Boutin, J. A. Tyrosine protein kinase inhibition and cancer. int. J. Biochem. 1994, 26, 1203-1226.
-
(1994)
Int. J. Biochem.
, vol.26
, pp. 1203-1226
-
-
Boutin, J.A.1
-
22
-
-
0028032074
-
Protein-tyrosine kinases: Potential targets for anticancer drug development
-
(c) Burke, T. R., Jr. Protein-tyrosine kinases: potential targets for anticancer drug development. Stem Cells 1994, 12, 1-6.
-
(1994)
Stem Cells
, vol.12
, pp. 1-6
-
-
Burke Jr., T.R.1
-
23
-
-
0026458235
-
Tyrophostins: Tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction
-
(d) Levitzki, A. Tyrophostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction. FASEB J. 1992, 6, 3275-3282.
-
(1992)
FASEB J
, vol.6
, pp. 3275-3282
-
-
Levitzki, A.1
-
24
-
-
0026578427
-
Protein-tyrosine kinase inhibitors
-
(e) Burke, T. R., Jr. Protein-tyrosine kinase inhibitors. Drugs Future 1992, 17, 19-131.
-
(1992)
Drugs Future
, vol.17
, pp. 19-131
-
-
Burke Jr., T.R.1
-
25
-
-
0026454471
-
Protein-tyrosine kinase inhibition: Mechanism-based discovery of antitumor agents
-
(f) Chang, C. J.; Geahlen, R. L. Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents. J. Nat. Prod. 1992, 55, 1529-1560.
-
(1992)
J. Nat. Prod.
, vol.55
, pp. 1529-1560
-
-
Chang, C.J.1
Geahlen, R.L.2
-
26
-
-
0018580807
-
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates
-
(a) Eckhart, W.; Hutchinson, M. A.; Hunter, T. An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates. Cell 1979, 18, 925-933.
-
(1979)
Cell
, vol.18
, pp. 925-933
-
-
Eckhart, W.1
Hutchinson, M.A.2
Hunter, T.3
-
27
-
-
0020519557
-
Polyoma virus transforming protein associates with the product of the c-src cellular gene
-
(b) Courtneidge, S. A.; Smith, A. E. Polyoma virus transforming protein associates with the product of the c-src cellular gene. Nature 1983, 303, 435-439.
-
(1983)
Nature
, vol.303
, pp. 435-439
-
-
Courtneidge, S.A.1
Smith, A.E.2
-
30
-
-
0026730978
-
Development and progression of human colon cancer
-
(b) Talamonti, M. S.; Curley, S. A.; Gallick, G. E. Development and progression of human colon cancer. Cancer Bull. 1992, 44, 321-326.
-
(1992)
Cancer Bull.
, vol.44
, pp. 321-326
-
-
Talamonti, M.S.1
Curley, S.A.2
Gallick, G.E.3
-
32
-
-
0027954475
-
Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice
-
(d) Guy, C. T.; Muthuswamy, S. K.; Cardiff, R. D.; Soriano, P. Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice. Genes Dev. 1994, 8, 23-32.
-
(1994)
Genes Dev.
, vol.8
, pp. 23-32
-
-
Guy, C.T.1
Muthuswamy, S.K.2
Cardiff, R.D.3
Soriano, P.4
-
33
-
-
0028174305
-
c-src with two major signaling pathways in human breast cancer
-
c-src with two major signaling pathways in human breast cancer. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 83-87.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 83-87
-
-
Lutrell, D.K.1
Lee, A.2
Lansing, T.J.3
Crosby, R.M.4
Jung, K.D.5
Willard, D.6
Luther, M.7
Rodriguez, M.8
-
34
-
-
0027369574
-
Increased expression of the src proto-oncogene in hairy cell leukemia and a subgroup of B-cell limphomas
-
(f) Lynch, S. A.; Bfrugge, J. S.; Fromowitz, F.; Glantz, L.; Viola, M. V. increased expression of the src proto-oncogene in hairy cell leukemia and a subgroup of B-cell limphomas. Leukemia 1993, 7, 1416-1422.
-
(1993)
Leukemia
, vol.7
, pp. 1416-1422
-
-
Lynch, S.A.1
Bfrugge, J.S.2
Fromowitz, F.3
Glantz, L.4
Viola, M.V.5
-
35
-
-
0028362398
-
Identification of tricyclic analogues related to ellagic acid as potent/selective tyrosine protein kinase inhibitors
-
(a) Dow, R. L.; Chow, T. T.; Bechle, B. M.; Larson, E. R. Identification of tricyclic analogues related to ellagic acid as potent/selective tyrosine protein kinase inhibitors. J. Med. Chem. 1994, 31, 2221-2231.
-
(1994)
J. Med. Chem.
, vol.31
, pp. 2221-2231
-
-
Dow, R.L.1
Chow, T.T.2
Bechle, B.M.3
Larson, E.R.4
-
37
-
-
0028143584
-
Intracellular concentrations of ATP can be as high as 5 μM
-
Traut, T. W. intracellular concentrations of ATP can be as high as 5 μM. Mol. Cell Biochem. 1994, 140, 1-22.
-
(1994)
Mol. Cell Biochem.
, vol.140
, pp. 1-22
-
-
Traut, T.W.1
-
38
-
-
0028789189
-
c-src
-
c-src. J. Med. Chem. 1995, 38, 4276-4283.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4276-4283
-
-
Nair, S.A.1
Kim, M.H.2
Warren, S.D.3
Choi, S.4
Songyang, Z.5
Cantley, L.C.6
-
39
-
-
0026419319
-
Generation and use of synthetic peptide libaries for basic research and drug discovery
-
(a) Houghten, R. A.; Pinilla, C.; Blondelle, S. E.; Cuervo, J. H. Generation and use of synthetic peptide libaries for basic research and drug discovery. Nature 1991, 354, 84-86.
-
(1991)
Nature
, vol.354
, pp. 84-86
-
-
Houghten, R.A.1
Pinilla, C.2
Blondelle, S.E.3
Cuervo, J.H.4
-
40
-
-
0024991625
-
Peptides on phage: A vast library of peptides for identifying ligands. Proc
-
(b) Cwirla, S. E.; Peters, E. A.; Barret, R. W.; Dower, W. J. Peptides on phage: a vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 6378-6382.
-
(1990)
Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 6378-6382
-
-
Cwirla, S.E.1
Peters, E.A.2
Barret, R.W.3
Dower, W.J.4
-
41
-
-
0026419328
-
A new type of synthetic peptide library for identifying ligand-binding activity
-
Lam, K. S.; Salmon, S. E.; Hersh, E. M.; Hruby, V. J.; Kazmiersky, W. M.; Knapp, R. J. A new type of synthetic peptide library for identifying ligand-binding activity. Nature 1991, 354, 82-84.
-
(1991)
Nature
, vol.354
, pp. 82-84
-
-
Lam, K.S.1
Salmon, S.E.2
Hersh, E.M.3
Hruby, V.J.4
Kazmiersky, W.M.5
Knapp, R.J.6
-
42
-
-
0029046713
-
Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases
-
Lam, K. S.; Wu, J.; Lou, Q. Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. int. J. Pept. Protein Res. 1995, 45, 587-592.
-
(1995)
Int. J. Pept. Protein Res.
, vol.45
, pp. 587-592
-
-
Lam, K.S.1
Wu, J.2
Lou, Q.3
-
44
-
-
0030915528
-
Asymmetric synthesis of unusual amino acids: Synthesis of four isomers of β-methyl-3-(2′-naphthyl)-alanine
-
Yuan, W.; Hruby, V. J. Asymmetric synthesis of unusual amino acids: Synthesis of four isomers of β-methyl-3-(2′-naphthyl)-alanine. Tetrahedron Lett. 1997, 38, 5853-5856.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 5853-5856
-
-
Yuan, W.1
Hruby, V.J.2
-
45
-
-
0027231813
-
β-turn topography
-
Ball, J. R.; Hughes, R. A. β-turn topography. Tetrahedron 1993, 49, 3467-3478.
-
(1993)
Tetrahedron
, vol.49
, pp. 3467-3478
-
-
Ball, J.R.1
Hughes, R.A.2
-
47
-
-
0030111325
-
A protein kinase assay for both acidic and basic peptides
-
Lou, Q.; Wu, J.; Lam, K. S. A protein kinase assay for both acidic and basic peptides. Anal. Biochem. 1996, 235, 107-109.
-
(1996)
Anal. Biochem.
, vol.235
, pp. 107-109
-
-
Lou, Q.1
Wu, J.2
Lam, K.S.3
-
48
-
-
0000440578
-
Bispenicillamine enkephalins possess highly improved specificity toward δ opiod receptors
-
Mosberg, H. I.; Hurst, T.; Hruby, V. J.; Yamamura, H. I. Bispenicillamine enkephalins possess highly improved specificity toward δ opiod receptors. Proc. Natl. Acad. Sci. U.S.A. 1983, 80, 5871-5874.
-
(1983)
Proc. Natl. Acad. Sci. U.S.A.
, vol.80
, pp. 5871-5874
-
-
Mosberg, H.I.1
Hurst, T.2
Hruby, V.J.3
Yamamura, H.I.4
-
49
-
-
0141837614
-
Peptides and mimics, design of conformationally constrained
-
Meyers, R. A., Ed.; VCH: Weinheim
-
Hruby, V. J.; Boteju, L. W. Peptides and mimics, design of conformationally constrained. In Encyclopedia of Molecular Biology and Molecular Medicine; Meyers, R. A., Ed.; VCH: Weinheim, 1996; Vol. 4, pp 371-382.
-
(1996)
Encyclopedia of Molecular Biology and Molecular Medicine
, vol.4
, pp. 371-382
-
-
Hruby, V.J.1
Boteju, L.W.2
-
50
-
-
0030884435
-
Design of peptides, proteins and peptidomimetics in chi space
-
Hruby, V. J.; Li, G.; Haskell-Luevano, C.; Shenderovich, M. Design of peptides, proteins and peptidomimetics in chi space. Biopolymers 1997, 43, 219-266.
-
(1997)
Biopolymers
, vol.43
, pp. 219-266
-
-
Hruby, V.J.1
Li, G.2
Haskell-Luevano, C.3
Shenderovich, M.4
-
51
-
-
0029740203
-
Probing the stereochemical requirements for receptor recognition of δ-opioid agonists through topographic modifications in position 1
-
(a) Qian, X.; Kövér, K. E.; Shenderovich, M. D.; Hruby, V. J. Probing the stereochemical requirements for receptor recognition of δ-opioid agonists through topographic modifications in position 1. J. Am. Chem. Soc. 1996, 775, 7282-7290.
-
(1996)
J. Am. Chem. Soc.
, vol.775
, pp. 7282-7290
-
-
Qian, X.1
Kövér, K.E.2
Shenderovich, M.D.3
Hruby, V.J.4
-
52
-
-
0028799933
-
Topographical modification of melanotropin peptide analogues with β-methyltryptophan isomers at position 9 leads to differential potencies and prolonged biological activities
-
(b) Haskell-Luevano, C.; Boteju, L. W.; Miwa, H.; Hadley, M. E.; Gantz, I.; Hruby, V. J. Topographical modification of melanotropin peptide analogues with β-methyltryptophan isomers at position 9 leads to differential potencies and prolonged biological activities. J. Med. Chem. 1995, 38, 4720-4729.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4720-4729
-
-
Haskell-Luevano, C.1
Boteju, L.W.2
Miwa, H.3
Hadley, M.E.4
Gantz, I.5
Hruby, V.J.6
-
53
-
-
0029993270
-
Topographical amino acid substitution in position 10 of glucagon analogues leads to antagonists/partial agonists with greater binding differences
-
(c) Azizeh, B. Y.; Shenderovich, M. D.; Trivedi, D.; Li, G.; Sturm, N. S.; Hruby, V. J. Topographical amino acid substitution in position 10 of glucagon analogues leads to antagonists/partial agonists with greater binding differences. J. Med. Chem. 1996, 39, 2449-2455.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 2449-2455
-
-
Azizeh, B.Y.1
Shenderovich, M.D.2
Trivedi, D.3
Li, G.4
Sturm, N.S.5
Hruby, V.J.6
-
54
-
-
0001534216
-
Conformational analysis of four β-methylphenylalanine stereoisomers in a bioactive peptide by z-filtered relay NMR
-
(a) Kövér, K. E.; Jiao, D.; Fang, S.; Hruby, V. J. Conformational analysis of four β-methylphenylalanine stereoisomers in a bioactive peptide by z-filtered relay NMR. Magn. Reson. Chem. 1993, 31, 1072-1076.
-
(1993)
Magn. Reson. Chem.
, vol.31
, pp. 1072-1076
-
-
Kövér, K.E.1
Jiao, D.2
Fang, S.3
Hruby, V.J.4
-
59
-
-
0027724577
-
In Vitro substrate specificity of protein tyrosine kinases
-
Cheng, H. C.; Matsura, I.; Wang, J. H. in Vitro substrate specificity of protein tyrosine kinases. Mol. Cell. Biochem. 1993, 127, 103-113.
-
(1993)
Mol. Cell. Biochem.
, vol.127
, pp. 103-113
-
-
Cheng, H.C.1
Matsura, I.2
Wang, J.H.3
-
60
-
-
0014772602
-
Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
-
Kaiser, E.; Colescott, R. L.; Bossinger, C. D.; Cook, P. J. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal. Biochem. 1970, 34, 595-598.
-
(1970)
Anal. Biochem.
, vol.34
, pp. 595-598
-
-
Kaiser, E.1
Colescott, R.L.2
Bossinger, C.D.3
Cook, P.J.4
-
61
-
-
0013579630
-
Optimization of disulfide bond formation
-
Misicka, A.; Hruby, V. J. Optimization of disulfide bond formation. Polish J. Chem. 1994, 68, 893-899.
-
(1994)
Polish J. Chem.
, vol.68
, pp. 893-899
-
-
Misicka, A.1
Hruby, V.J.2
|