메뉴 건너뛰기




Volumn 57, Issue 10, 1997, Pages 1877-1881

Potent pseudosubstrate-based peptide inhibitors for p60(c-src) protein tyrosine kinase

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN INHIBITOR; PROTEIN KINASE P60; SYNTHETIC PEPTIDE;

EID: 0030963144     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (23)

References (40)
  • 1
    • 0027716791 scopus 로고
    • The Src family of tyrosine protein kinases in hemopoietic signal transduction
    • Tsygankow, A., and Bolen, J. The Src family of tyrosine protein kinases in hemopoietic signal transduction. Stem Cells, 11: 371-380, 1993.
    • (1993) Stem Cells , vol.11 , pp. 371-380
    • Tsygankow, A.1    Bolen, J.2
  • 2
    • 0027353561 scopus 로고
    • Protein tyrosine kinase growth factor receptors and their ligands in development, and differentiation, and cancer
    • Wilkis, A. F. Protein tyrosine kinase growth factor receptors and their ligands in development, and differentiation, and cancer. Adv. Cancer Res., 60: 43-73, 1993.
    • (1993) Adv. Cancer Res. , vol.60 , pp. 43-73
    • Wilkis, A.F.1
  • 3
    • 37049183697 scopus 로고
    • Human breast cancer. Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Washington DC
    • Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. Human breast cancer. Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Washington DC), 235: 177-182, 1987.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 4
    • 0021674862 scopus 로고
    • An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity
    • Konopka, J. B., Watanabe, S., and Witte, O. N. An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell, 37: 1035-1042, 1984.
    • (1984) Cell , vol.37 , pp. 1035-1042
    • Konopka, J.B.1    Watanabe, S.2    Witte, O.N.3
  • 6
    • 0022542478 scopus 로고
    • Over-expression of the EGF receptor is a hallmark of squamous cell carcinoma
    • Ozanne, B., Richard, C. S., Hendler, F., Burns, D., and Gusterson, B. Over-expression of the EGF receptor is a hallmark of squamous cell carcinoma. J. Pathol., 149: 9-14, 1986.
    • (1986) J. Pathol. , vol.149 , pp. 9-14
    • Ozanne, B.1    Richard, C.S.2    Hendler, F.3    Burns, D.4    Gusterson, B.5
  • 10
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Washington DC
    • Levitzki, A., and Gazit, A. Tyrosine kinase inhibition: an approach to drug development. Science (Washington DC), 267: 1782-1787, 1995.
    • (1995) Science , vol.267 , pp. 1782-1787
    • Levitzki, A.1    Gazit, A.2
  • 11
    • 27644447540 scopus 로고    scopus 로고
    • Recent advances in tyrosine kinase inhibitors
    • Fry, D. W. Recent advances in tyrosine kinase inhibitors. Annu. Rep. Med. Chem., 31: 151-160, 1996.
    • (1996) Annu. Rep. Med. Chem. , vol.31 , pp. 151-160
    • Fry, D.W.1
  • 12
    • 0026454471 scopus 로고
    • Protein-tyrosine kinase inhibition: Mechanism-based discovery of anti-tumor agents
    • Chang, C., and Geahlen, R. L. Protein-tyrosine kinase inhibition: mechanism-based discovery of anti-tumor agents. J. Natl. Prod., 55: 1529-1590, 1992.
    • (1992) J. Natl. Prod. , vol.55 , pp. 1529-1590
    • Chang, C.1    Geahlen, R.L.2
  • 13
    • 0028032074 scopus 로고
    • Protein-tyrosine kinase: Potential targets for anticancer drug development
    • Burke, T. R., Jr. Protein-tyrosine kinase: potential targets for anticancer drug development. Stem Cells, 12: 1-6, 1994.
    • (1994) Stem Cells , vol.12 , pp. 1-6
    • Burke Jr., T.R.1
  • 15
    • 0028362398 scopus 로고
    • Identification of tricyic analogs related to ellagic acid as potent/selective tyrosine protein kinase inhibitors
    • Dow, R. L., Chou, T. T., Bechle, B. M., Goddard, C., and Larson, E. R. Identification of tricyic analogs related to ellagic acid as potent/selective tyrosine protein kinase inhibitors. J. Med. Chem., 37: 2224-2231, 1994.
    • (1994) J. Med. Chem. , vol.37 , pp. 2224-2231
    • Dow, R.L.1    Chou, T.T.2    Bechle, B.M.3    Goddard, C.4    Larson, E.R.5
  • 17
    • 0028180234 scopus 로고
    • 4,5-Dianilinophthalimide: A protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity
    • Buchdunger, E., Trinks, U., Mett, H., Regenass, U., Muller, M., Meyer, T., McGlynn, E., Pinna, L. A., Traxler, P., and Lydon, N. B. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc. Natl. Acad. Sci. USA, 91: 2334-2338, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2334-2338
    • Buchdunger, E.1    Trinks, U.2    Mett, H.3    Regenass, U.4    Muller, M.5    Meyer, T.6    McGlynn, E.7    Pinna, L.A.8    Traxler, P.9    Lydon, N.B.10
  • 18
    • 0028243048 scopus 로고
    • A new series of PDGF receptor tyrosine kinase inhibitors: 3-substituted quinoline derivatives
    • Maguire, M. P., Sheets, K. R., McVety, K., Spada, A. P., and Zilberstein, A. A new series of PDGF receptor tyrosine kinase inhibitors: 3-substituted quinoline derivatives. J. Med. Chem., 37: 2129-2137, 1994.
    • (1994) J. Med. Chem. , vol.37 , pp. 2129-2137
    • Maguire, M.P.1    Sheets, K.R.2    McVety, K.3    Spada, A.P.4    Zilberstein, A.5
  • 20
    • 0029123125 scopus 로고
    • Tyrosine kinase inhibitors. 7. 7-Amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidines: A new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor
    • Thompson, A. M., Bridges, A. J., Fry, D. W., Kraker, A. J., and Denny, W. A. Tyrosine kinase inhibitors. 7. 7-Amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidines: a new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. J. Med. Chem., 38: 3780-3788, 1995.
    • (1995) J. Med. Chem. , vol.38 , pp. 3780-3788
    • Thompson, A.M.1    Bridges, A.J.2    Fry, D.W.3    Kraker, A.J.4    Denny, W.A.5
  • 21
    • 0028968622 scopus 로고
    • Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class
    • Buchdunger, E., Zimmermann, J., Mett, H., Meyer, T., Muller, M., Regenass, R., and Lydon, N. B. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc. Natl. Acad. Sci. USA, 92: 2558-2562, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2558-2562
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3    Meyer, T.4    Muller, M.5    Regenass, R.6    Lydon, N.B.7
  • 22
    • 0029130763 scopus 로고
    • Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5′-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor
    • Rewcastle, G. W., Denny, W. A., Bridges, A. J., Zhou, H., Cody, D. R., McMichael, A., and Fry, D. W. Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl)amino]- and 4-(phenylamino)quinazolines as potent adenosine 5′-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor. J. Med. Chem., 38: 3482-3487, 1995.
    • (1995) J. Med. Chem. , vol.38 , pp. 3482-3487
    • Rewcastle, G.W.1    Denny, W.A.2    Bridges, A.J.3    Zhou, H.4    Cody, D.R.5    McMichael, A.6    Fry, D.W.7
  • 24
    • 0029896163 scopus 로고    scopus 로고
    • Regulation, substrates and functions of Src
    • Brown, M. T., and Cooper, J. A. Regulation, substrates and functions of Src. Biochim. Biophys. Acta, 1287: 121-149, 1996.
    • (1996) Biochim. Biophys. Acta , vol.1287 , pp. 121-149
    • Brown, M.T.1    Cooper, J.A.2
  • 25
    • 0029046713 scopus 로고
    • Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases
    • Lam, K. S., Wu, J. Z., and Lou, Q. Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. Int. J. Pept. Protein Res., 45: 587-592, 1995.
    • (1995) Int. J. Pept. Protein Res. , vol.45 , pp. 587-592
    • Lam, K.S.1    Wu, J.Z.2    Lou, Q.3
  • 28
    • 0028556408 scopus 로고
    • Identifying substrate motifs of protein kinases by a random library approach
    • Wu, J. Z., Ma, Q. N., and Lam, K. S. Identifying substrate motifs of protein kinases by a random library approach. Biochemistry, 33: 14825-14833, 1994.
    • (1994) Biochemistry , vol.33 , pp. 14825-14833
    • Wu, J.Z.1    Ma, Q.N.2    Lam, K.S.3
  • 31
    • 0026059319 scopus 로고
    • Pseudosubstrate-based peptide inhibitors
    • Kemp, B. E., and Pearson, R. B., and House, C. M. Pseudosubstrate-based peptide inhibitors. Methods Enzymol., 200: 287-316, 1991.
    • (1991) Methods Enzymol. , vol.200 , pp. 287-316
    • Kemp, B.E.1    Pearson, R.B.2    House, C.M.3
  • 34
    • 0030111325 scopus 로고    scopus 로고
    • A protein kinase assay system for both acidic and basic peptides
    • Lou, Q., Wu, J. Z., and Lam, K. S. A protein kinase assay system for both acidic and basic peptides. Anal. Biochem., 235: 107-109, 1996.
    • (1996) Anal. Biochem. , vol.235 , pp. 107-109
    • Lou, Q.1    Wu, J.Z.2    Lam, K.S.3
  • 35
    • 15444350366 scopus 로고    scopus 로고
    • The protein kinase: Protein-tyrosine kinases
    • San Diego, CA: Academic Press
    • Hardie, G., and Hanks, S. The protein kinase: protein-tyrosine kinases. Facts Book, pp. 7-47. San Diego, CA: Academic Press, 1996.
    • (1996) Facts Book , pp. 7-47
    • Hardie, G.1    Hanks, S.2
  • 36
    • 0006912117 scopus 로고    scopus 로고
    • Development of a selective pseudosubstrate-based peptide inhibitor of p60c-src protein tyrosine kinase
    • Wu, J. Z., Phan, H., Salmon S. E., and Lam, K. S. Development of a selective pseudosubstrate-based peptide inhibitor of p60c-src protein tyrosine kinase. Lett. Pept. Sci., 3: 309-316, 1996.
    • (1996) Lett. Pept. Sci. , vol.3 , pp. 309-316
    • Wu, J.Z.1    Phan, H.2    Salmon, S.E.3    Lam, K.S.4
  • 37
    • 0027724577 scopus 로고
    • In vitro substrate specificity of protein tyrosine kinases
    • Cheng, H. C., Matsuura, I., and Wang, J. H. In vitro substrate specificity of protein tyrosine kinases. Mol. Cell. Biochem., 127/128: 103-113, 1993.
    • (1993) Mol. Cell. Biochem. , vol.127-128 , pp. 103-113
    • Cheng, H.C.1    Matsuura, I.2    Wang, J.H.3
  • 38
    • 0031025991 scopus 로고    scopus 로고
    • Three-dimensional structure of the tyrosine kinase c-scr
    • Xu, W., Harrison, S. C., and Eck, M. J. Three-dimensional structure of the tyrosine kinase c-scr. Nature (Lond.), 385: 595-602, 1996.
    • (1996) Nature (Lond.) , vol.385 , pp. 595-602
    • Xu, W.1    Harrison, S.C.2    Eck, M.J.3
  • 39
    • 0026733512 scopus 로고
    • Comparison of scr-family cDNAs reveals distinct mechanisms unlerlying focus formation in transfected fibroblasts
    • Sartor, O., McLellan, C. A., and Chiueh, T. Comparison of scr-family cDNAs reveals distinct mechanisms unlerlying focus formation in transfected fibroblasts. J. Biol. Chem., 267: 21044-21051, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21044-21051
    • Sartor, O.1    McLellan, C.A.2    Chiueh, T.3
  • 40
    • 0027452347 scopus 로고
    • Substrate specificity for normal but not mutationally activated variants of src family kinases
    • Sartor, O., and Robbins, K. C. Substrate specificity for normal but not mutationally activated variants of src family kinases. J. Biol. Chem., 268: 21014-21020, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21014-21020
    • Sartor, O.1    Robbins, K.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.