메뉴 건너뛰기




Volumn 188, Issue 4, 1998, Pages 773-778

Glycan-regulated antigen processing of a protein in the endoplasmic reticulum can uncover cryptic cytotoxic T cell epitopes

Author keywords

Antigen processing; Class I major histocompatibility complex; Cytotoxic T lymphocyte; Endoplasmic reticulum; Transporter associated with antigen processing

Indexed keywords

ANTIGEN; EPITOPE; GLYCAN; NUCLEOPROTEIN; PROTEIN;

EID: 0032541487     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.4.773     Document Type: Article
Times cited : (30)

References (25)
  • 1
    • 0027258002 scopus 로고
    • Antigen processing. Peptides and the proteasome
    • Howard, J.C., and A. Seelig. 1993. Antigen processing. Peptides and the proteasome. Nature. 365:211-212.
    • (1993) Nature , vol.365 , pp. 211-212
    • Howard, J.C.1    Seelig, A.2
  • 2
    • 0030843345 scopus 로고    scopus 로고
    • Transporter associated with antigen processing
    • Elliott, T. 1997. Transporter associated with antigen processing. Adv. Immunol. 65:47-109.
    • (1997) Adv. Immunol. , vol.65 , pp. 47-109
    • Elliott, T.1
  • 3
    • 0028925556 scopus 로고
    • Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum
    • Elliott, T., A. Willis, V. Cerundolo, and A. Townsend. 1995. Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum. J. Exp. Med. 181:1481-1491.
    • (1995) J. Exp. Med. , vol.181 , pp. 1481-1491
    • Elliott, T.1    Willis, A.2    Cerundolo, V.3    Townsend, A.4
  • 4
    • 0028096715 scopus 로고
    • Trimming of antigenic peptides in an early secretory compartment
    • Snyder, H.L., J.W. Yewdell, and J.R. Bennink. 1994. Trimming of antigenic peptides in an early secretory compartment. J. Exp. Med. 180:2389-2394.
    • (1994) J. Exp. Med. , vol.180 , pp. 2389-2394
    • Snyder, H.L.1    Yewdell, J.W.2    Bennink, J.R.3
  • 5
    • 1842407159 scopus 로고    scopus 로고
    • Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing
    • Snyder, H.L., I. Bacik, J.R. Bennink, G. Kearns, T.W. Behrens, T. Bachi, M. Orlowski, and J.W. Yewdell. 1997. Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing. J. Exp. Med. 186:1087-1098.
    • (1997) J. Exp. Med. , vol.186 , pp. 1087-1098
    • Snyder, H.L.1    Bacik, I.2    Bennink, J.R.3    Kearns, G.4    Behrens, T.W.5    Bachi, T.6    Orlowski, M.7    Yewdell, J.W.8
  • 6
    • 0030239693 scopus 로고    scopus 로고
    • Defective ribosomal products (DRiPs): A major source of antigenic peptides for MHC class I molecules?
    • Yewdell, J.W., L.C. Anton, and J.R. Bennink. 1996. Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules? J. Immunol. 157:1823-1826.
    • (1996) J. Immunol. , vol.157 , pp. 1823-1826
    • Yewdell, J.W.1    Anton, L.C.2    Bennink, J.R.3
  • 7
    • 0022972506 scopus 로고
    • Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence
    • Townsend, A.R., J. Bastin, K. Gould, and C.G. Brownlee. 1986. Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence. Nature. 324:575-577.
    • (1986) Nature , vol.324 , pp. 575-577
    • Townsend, A.R.1    Bastin, J.2    Gould, K.3    Brownlee, C.G.4
  • 8
    • 1842290406 scopus 로고    scopus 로고
    • Introduction of a glycosylation site into a secreted protein provides evidence for an alternative antigen processing pathway: Transport of precursors of major histocompatibility complex class I-restricted peptides from the endoplasmic reticulum to the cytosol
    • Bacík, I., H.L. Snyder, L.C. Antón, G. Russ, W. Chen, J.R. Bennink, L. Urge, L. Otvos, B. Dudkowska, L. Eisenlohr, and J.W. Yewdell. 1997. Introduction of a glycosylation site into a secreted protein provides evidence for an alternative antigen processing pathway: transport of precursors of major histocompatibility complex class I-restricted peptides from the endoplasmic reticulum to the cytosol. J. Exp. Med. 186: 479-487.
    • (1997) J. Exp. Med. , vol.186 , pp. 479-487
    • Bacík, I.1    Snyder, H.L.2    Antón, L.C.3    Russ, G.4    Chen, W.5    Bennink, J.R.6    Urge, L.7    Otvos, L.8    Dudkowska, B.9    Eisenlohr, L.10    Yewdell, J.W.11
  • 9
    • 0031973735 scopus 로고    scopus 로고
    • The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol
    • Mosse, C.A., L. Meadows, C.J. Luckey, D.J. Kittlesen, E.L. Huczko, C.L. Slingluff, J. Shabanowitz, D.F. Hunt, and V.H. Engelhard. 1998. The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol. J. Exp. Med. 187:37-48.
    • (1998) J. Exp. Med. , vol.187 , pp. 37-48
    • Mosse, C.A.1    Meadows, L.2    Luckey, C.J.3    Kittlesen, D.J.4    Huczko, E.L.5    Slingluff, C.L.6    Shabanowitz, J.7    Hunt, D.F.8    Engelhard, V.H.9
  • 10
    • 0029828991 scopus 로고    scopus 로고
    • Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
    • Wiertz, E.J., D. Tortorella, M. Bogyo, J. Yu, W. Mothes, T.R. Jones, T.A. Rapoport, and H.L. Ploegh. 1996. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384: 432-438.
    • (1996) Nature , vol.384 , pp. 432-438
    • Wiertz, E.J.1    Tortorella, D.2    Bogyo, M.3    Yu, J.4    Mothes, W.5    Jones, T.R.6    Rapoport, T.A.7    Ploegh, H.L.8
  • 11
    • 0026576422 scopus 로고
    • HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides
    • Wei, M.L., and P. Cresswell. 1992. HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. Nature. 356:443-446.
    • (1992) Nature , vol.356 , pp. 443-446
    • Wei, M.L.1    Cresswell, P.2
  • 14
    • 0027237066 scopus 로고
    • Transporter-independent processing of HIV-1 envelope protein for recognition by CD8+ T cells
    • Hammond, S.A., R.C. Bollinger, T.W. Tobery, and R.F. Silliciano. 1993. Transporter-independent processing of HIV-1 envelope protein for recognition by CD8+ T cells. Nature. 364:158-161.
    • (1993) Nature , vol.364 , pp. 158-161
    • Hammond, S.A.1    Bollinger, R.C.2    Tobery, T.W.3    Silliciano, R.F.4
  • 15
    • 0029907090 scopus 로고    scopus 로고
    • Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen
    • Gueguen, M., and E.O. Long. 1996. Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen. Proc. Natl. Acad. Sci. USA. 93:14692-14697.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14692-14697
    • Gueguen, M.1    Long, E.O.2
  • 16
    • 0029924928 scopus 로고    scopus 로고
    • Recognition of out-of-frame major histocompatibility complex class I-restricted epitopes in vivo
    • Elliott, T., H. Bodmer, and A. Townsend. 1996. Recognition of out-of-frame major histocompatibility complex class I-restricted epitopes in vivo. Eur. J. Immunol. 26:1175-1179.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1175-1179
    • Elliott, T.1    Bodmer, H.2    Townsend, A.3
  • 17
    • 0018652553 scopus 로고
    • Fine specificity analysis with monoclonal antibodies of antigens controlled by the major histocompatibility complex and by the Qa/TL region in mice
    • Lemke, H., G.J. Hammerling, and U. Hammerling. 1979. Fine specificity analysis with monoclonal antibodies of antigens controlled by the major histocompatibility complex and by the Qa/TL region in mice. Immunol. Rev. 47:175-206.
    • (1979) Immunol. Rev. , vol.47 , pp. 175-206
    • Lemke, H.1    Hammerling, G.J.2    Hammerling, U.3
  • 18
    • 0022129512 scopus 로고
    • Cytotoxic T cells recognize fragments of the influenza nucleoprotein
    • Townsend, A.R., F.M. Gotch, and J. Davey. 1985. Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell. 42:457-467.
    • (1985) Cell , vol.42 , pp. 457-467
    • Townsend, A.R.1    Gotch, F.M.2    Davey, J.3
  • 19
    • 0027336845 scopus 로고
    • k-restricted cytotoxic T cell epitope in the NS1 protein of influenza virus using an MHC allele-specific motif
    • k-restricted cytotoxic T cell epitope in the NS1 protein of influenza virus using an MHC allele-specific motif. Virology. 193:289-295.
    • (1993) Virology , vol.193 , pp. 289-295
    • Cossins, J.1    Gould, K.G.2    Smith, M.3    Driscoll, P.4    Brownlee, G.G.5
  • 20
    • 0026335733 scopus 로고
    • An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein
    • Tsomides, T.J., B.D. Walker, and H.N. Eisen. 1991. An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc. Natl. Acad. Sci. USA. 88:11276-11280.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11276-11280
    • Tsomides, T.J.1    Walker, B.D.2    Eisen, H.N.3
  • 21
    • 0024095276 scopus 로고
    • Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen
    • Townsend, A., J. Bastin, K. Gould, G. Brownlee, M. Andrew, B. Coupar, D. Boyle, S. Chan, and G. Smith. 1988. Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. J. Exp. Med. 168:1211-1224.
    • (1988) J. Exp. Med. , vol.168 , pp. 1211-1224
    • Townsend, A.1    Bastin, J.2    Gould, K.3    Brownlee, G.4    Andrew, M.5    Coupar, B.6    Boyle, D.7    Chan, S.8    Smith, G.9
  • 22
    • 0024246812 scopus 로고
    • Recognition of influenza a matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site
    • Gotch, F., A. McMichael, and J. Rothbard, 1988. Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site. J. Exp. Med. 168: 2045-2057.
    • (1988) J. Exp. Med. , vol.168 , pp. 2045-2057
    • Gotch, F.1    McMichael, A.2    Rothbard, J.3
  • 23
    • 0030198868 scopus 로고    scopus 로고
    • Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP
    • Lewis, J.W., A. Neisig, J. Neefjes, and T. Elliott. 1996. Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP. Curr. Biol. 6:873-883.
    • (1996) Curr. Biol. , vol.6 , pp. 873-883
    • Lewis, J.W.1    Neisig, A.2    Neefjes, J.3    Elliott, T.4
  • 24
    • 0031032422 scopus 로고    scopus 로고
    • The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells
    • Cerundolo, V., A. Benham, V. Braud, S. Mukherjee, K. Gould, B. Macino, J. Neefjes, and A. Townsend. 1997. The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells. Eur. J. Immunol. 27:336-342.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 336-342
    • Cerundolo, V.1    Benham, A.2    Braud, V.3    Mukherjee, S.4    Gould, K.5    Macino, B.6    Neefjes, J.7    Townsend, A.8
  • 25
    • 0029062090 scopus 로고
    • An epitope selective transporter associated with antigen processing (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL
    • Hammond, S.A., P.R. Johnson, S.A. Kalams, B.D. Walker, M. Takiguchi, J.T. Safrit, R.A. Koup, and R.F. Siliciano. 1995. An epitope selective transporter associated with antigen processing (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL. J. Immunol. 154:6140-6156.
    • (1995) J. Immunol. , vol.154 , pp. 6140-6156
    • Hammond, S.A.1    Johnson, P.R.2    Kalams, S.A.3    Walker, B.D.4    Takiguchi, M.5    Safrit, J.T.6    Koup, R.A.7    Siliciano, R.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.