Synthesis of α-aryl N-adamant-1-yl nitrones and using them for spin trapping of hydroxyl radicals

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 4, 1998, Pages 379-384

  Sár, Cecília P ^a   Hideg, Éva ^b   Vass, Imre ^b   Hideg, Kálmán ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

^b INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMANTANE; FREE RADICAL; HYDROXYL RADICAL; NITRONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG SYNTHESIS; NONHUMAN; SOLUBILITY; SPIN TRAPPING;

ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; HYDROXYL RADICAL; NITROGEN OXIDES; SPIN LABELS;

EID: 0032539568     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00033-X     Document Type: Article

References (19)

1. 1. Halliwell, B.; Gutteridge, J.M.C. In Methods in Enzymology; Packer, L.; Glazer, A.N., Eds.; Academic Press: London, 1990; Vol. 186, pp. 1-85.
2. 2. Pryor, W.A.; Jin, X.; Squadrito, G.L. Proc. Natl. Acad. Sci. USA 1994, 91, 1173.
3. 3. Halliwell, B.; Gutteridge, J.M.C. Free Radicals in Biology and Medicine (2nd ed.) Calderon Press: Oxford, 1989.
4. 4. Janzen, E.G.; Haire, D.L. In Advances in Free Radical Chemistry; Tanner, D., Ed.; JAI Press: Greenwich, CT, 1990; Vol. 1, pp 253.
5. 5. Ohya-Nishiguchi, H. In Bioradicals Detected by ESR Spectroscopy; Ohya-Nishiguchi, H.; Packer, L., Eds.; Birkhauser Verlag: Basel, 1995; pp 1-17.
6. 6. Mottley, C.; Mason, R.P. In Biological Magnetic Resonance; Berliner, L.J.; Reuben, J., Eds.; Plenum Publishers: New York, NY, 1989; Vol 8, pp 489-546.
7. 7. Matasyoh, J.C.; Schuler, P.; Stegmann, H.B.; Poyer, J.L.; West, M.; Janzen, E.G. Magn. Reson. in Chem. 1996, 34, 351.
8. 8. Sankuratri, N.; Kotake, Y.; Janzen, E.G. Free Rad. Biol. Med. 1996, 21, 889.
9. 9. Sankuratri, N.; Janzen, E.G. Tetrahedron Letters 1996, 37, 5313.
10. 10. Thomas, C.E.; Ohlweiler, D.F.; Carr, A.A.; Nieduzak, T.R.; Hay, D.A.; Adams, G.; Vaz, R.; Bernotas, R.C. J. Biol. Chem. 1996, 271, 3097.
11. 11. Janzen, E.G.; Liu, J. I.-P. J. Magn. Reson. 1973, 9, 510.
12. 12. Janzen, E.G. Acc. Chem. Res. 1971, 4, 31.
13. 13. Haire, D.L.; Oehler, U.M.; Krygsman, P.H.; Janzen, E.G. J. Org. Chem. 1988, 53, 4535.
14. 14. Janzen, E.G.; Wang, Y.Y.; Shetty, R.V. J. Am. Chem. Soc. 1978, 100, 2923.
15. 15. Carmichael, A.J.; Makino, K.; Riesz, P. Radiat. Res, 1984, 100, 222.
16. 16. Kotake, Y.; Janzen, E.G. J. Am. Chem. Soc. 1991, 113, 9503.
17. 17. Settimo, A.; Marini, A.M.; Primofiore, G.; Settimo, F. Il Farmaco 1995, 50, 321.
18. 18. Väczi, L.; Hankovszky, H.O.; Hideg, K.; Hadházy, Gy. Acta Microbiol. Acad. Sci. Hung. 1973, 20, 241.
19. 19. Sár, C.P.; Kálai, T.; Bárácz, N.M.; Jerkovich, Gy.; Hideg, K. Synth. Comm. 1995, 25, 2929.