Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human

Toxicology Letters

Volumn 95, Issue 2, 1998, Pages 123-129

  Nieusma, Joe L ^a   Claffey, David J ^a   Koop, Dennis R ^b   Chen, Weiqiao ^c   Peter, Raimund M ^c   Nelson, Sidney D ^c   Ruth, James A ^a   Ross, David ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

1,3 Butadiene; Butadiene monoxide; Cytochrome P450 2E1; Metabolism; Purified reconstituted enzyme systems; Stereochemistry

Indexed keywords

1,2 EPOXY 3 BUTENE; 1,3 BUTADIENE; 1,3 BUTADIENE DERIVATIVE; CARCINOGEN; CYTOCHROME P450; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENANTIOMER; EXHAUST GAS; GAS CHROMATOGRAPHY; HUMAN; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; OXIDATION; PLASTIC INDUSTRY; PRIORITY JOURNAL; RABBIT; RAT; RISK ASSESSMENT; RUBBER INDUSTRY; STEREOCHEMISTRY; STEREOISOMERISM; TOXICITY TESTING;

EID: 0032536735     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0378-4274(98)00026-5     Document Type: Article

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