Comparison of mouse strains for susceptibility to styrene-induced hepatotoxicity and pneumotoxicity

Journal of Toxicology and Environmental Health

Volumn 51, Issue 2, 1997, Pages 177-187

  Carlson, Gary P ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA GLUTAMYLTRANSFERASE; IDITOL DEHYDROGENASE; LACTATE DEHYDROGENASE; STYRENE; STYRENE OXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG SENSITIVITY; IN VITRO STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER INJURY; LIVER TOXICITY; LUNG TOXICITY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; GAMMA-GLUTAMYLTRANSFERASE; L-IDITOL 2-DEHYDROGENASE; L-LACTATE DEHYDROGENASE; LIVER; LUNG; MALE; MICE; MICE, INBRED A; MICE, INBRED C57BL; MICE, INBRED ICR; MICROSOMES, LIVER; SPECIES SPECIFICITY; STYRENE; STYRENES;

EID: 0030995364     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/00984109708984020     Document Type: Article

References (26)

1. Bond, J. A. 1989. Review of the toxicology of styrene. Crit. Rev. Toxicol. 19:227-249.
2. Cai, J., Myers, S. R. and Hurst, H. E. 1995. Measurement of the hemoglobin N-α2-oxoethyljvaline adduct in ethyl carbamate treated mice. Toxicol. Appl. Pharmacol. 131:73-79.
3. Carlson, C. P. and Day, B. J. 1992. Induction by pyridine of cytochrome P450IIE1 and xenobi-otic metabolism in rat lung and liver. Pharmacology 44:117-123.
4. Foureman, G. L., Harris, C., Guengerich, F. P. and Bend, J. R. 1989. Stereochemistry of styrene oxidation in microsomes and in purified cytochrome P-450 enzymes from rat liver. J. Pharmacol. Exp. Ther. 248:492-497.
5. Gadberry, M. G., DeNicola, D. B. and Carlson, G. P. 1996. Pneumotoxicity and hepatotoxicity of styrene and styrene oxide. J. Toxicol. Environ. Health 48:273-294.
6. Gerlach, U. 1983. Sorbitol dehydrogenase. In Methods of enzymatic analysis, ed. H. U. Bergmeyer, 3rd ed., pp. 112-117. Weinheim: Verlag Chemie.
7. Harris, C., Philpot, R. M., Hernandez, O. and Bend, J. R. 1986. Rabbit pulmonary cytochrome P-450 monooxygenase system: Isozyme differences in the rate and stereoselectivity of styrene oxidation. J. Pharmacol. Exp. Ther. 236:144-149.
8. Iba, M. M., Ghosal, A., Thomas, P. E., Bennett, S. and Storch, A. 1993. Tissue microsomal P450 levels in rats exposed to acetone and pyridine. Toxicologist 13:345.
9. Kaul, K. L. and Novak, R. F. 1987. Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine. J. Pharmacol. Exp. Ther. 243:384-390.
10. Kim, H., Putt, D., Reddy, S., Hollenberg, P. F. and Novak, R. F. 1993. Enhanced expression of rat hepatic CYP2B1/2B2 and 2E1 by pyridine: Differential induction kinetics and molecular basis of expression. J. Pharmacol. Exp. Ther. 267:927-936.
11. Kim, S. G., Philpot, R. M. and Novak, R. F. 1991. Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: Characterization of high- and low-affinity pyridine A/-oxygenases. J. Pharmacol. Exp. Ther. 259:470-477.
12. Leibman, K. C. and Ortiz, E. 1968. Styrene epoxide. An intermediate in microsomal oxidation of styrene to its glycol. Pharmacologist 10:203.
13. Malkinson, A. M., Nesbitt, M. N. and Skamene, E. 1985. Susceptibility to urethan-induced pulmonary adenomas between A/J and C57BL/6J mice: Use of AXB and BXA recombinant inbred lines indicating a three-locus genetic model. J. Natl. Cancer Inst. 75:971-974.
14. Miller, R. R., Newhook, R. and Poole, A. 1994. Styrene production, use and human exposure. Crit. Rev. Toxicol. 24(51):51-510.
15. Morgan, D. L., Mahler, J. F., O'Connor, R. W., Price, H. C. and Adkins, B. 1993a. Styrene inhalation toxicity studies in mice. I. Hepatotoxicity in B6C3F1 mice. Fundal. Appl. Toxicol. 20:325-335.
16. Morgan, D. L., Mahler, J. F., Dill, J. A., Price, H. C., O'Connor, R. W. and Adkins, B. 1993b. Styrene inhalation toxicity studies in mice. III. Strain differences in susceptibility. Fundam. Appl. Toxicol. 21:326-333.
17. Morgan, D. L., Mahler, J. F., Moorman, M. P., Wilson, R. E., Price, H. C., Jr., Richards, J. H. and O'conner, R. W. 1995. Comparison of styrene hepatotoxicity in B6C3F1 and Swiss mice. Fundam. Appl. Toxicol. 27:217-222.
18. Nakajima, T., Wang, R. S., Elovaara, E., Gonzalez, F. J., Gelboin, H. V., Vainio, H. and Aoyama, T. 1994a. CYP2C11 and CYP2B1 are major cytochrome P450 forms involved in styrene oxidation in liver and lung microsomes from untreated rats, respectively. Biochem. Pharmacol. 48:637-642.
19. Nakajima, T., Elovaara, E., Gonzalez, F. J., Gelboin, H. V., Raunio, H., Pelkonen, O., Vainio, H. and Aoyama, T. 1994b. Styrene metabolism by cDNA-expressed human hepatic and pulmonary cytochromes P450. Chem. Res. Toxicol. 7:891-896.
20. Oesch, F., Jerina, D. M., Daly, J. W. and Rice, J. M. 1973. Induction, activation and inhibition of epoxide hydrase: An anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase. Chem.-Biol. Interact. 6:189-202.
21. Page, D. A. and Carlson, G. P. 1994. The effect of pyridine on the in vitro and in vivo metabolism of ethyl carbamate (urethane) by rat and mouse. Carcinogenesis 15:2177-2181.
22. Reinke, L. A. and Moyer, M. J. 1985. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drug Metab. Dispos. 13:538-552.
23. l4C-styrene oxide. Environ. Health Perspect. 17:135-144.
24. Smith, G. D., Ding, J. L. and Peters, T. J. 1979. A sensitive fluorimetric assay for gamma-glutamyl transferase. Anal. Biochem. 100:136-139.
25. Vassault, A. 1983. Lactate dehydrogenase. UV-method with pyruvate and NADH. In Methods of enzymatic analysis, ed. H. U. Bergmeyer, 3rd ed., pp. 118-125. Weinheim: Verlag Chemie.
26. Watabe, T., Ozawa, N. and Hiratsuka, A. 1983. Studies on metabolism and toxicity of styrene-VI. Regioselectivity in glutathione S-conjugation and hydrolysis of racemic, R- and 5-phenyl-oxiranes in rat liver. Biochem. Pharmacol. 32:777-785.