Genetic selection of mouse lines differing in sensitivity to a benzodiazepine receptor inverse agonist

Brain Research

Volumn 787, Issue 1, 1998, Pages 85-90

  Chapouthier, Georges ^a,c   Launay, Jean Marie ^b   Venault, Patrice ^a,c   Breton, Catherine ^a   Roubertoux, Pierre L ^a   Crusio, Wim E ^a  

^a CNRS   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Behavioral neurogenetics; Benzodiazepine receptor; Convulsion; Genetic selection; Methyl carboline 3 carboxylate; Mouse

Indexed keywords

BENZODIAZEPINE RECEPTOR STIMULATING AGENT; BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREEDING; CONTROLLED STUDY; CONVULSION; GENETIC SELECTION; LATENT PERIOD; MALE; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; SEIZURE;

ANIMALS; CARBOLINES; CONVULSANTS; FEMALE; FLUMAZENIL; GABA AGENTS; MALE; MICE; MICE, INBRED STRAINS; RADIOLIGAND ASSAY; SELECTION (GENETICS); SPECIES SPECIFICITY;

EID: 0032536710     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01483-2     Document Type: Article

References (31)

1. [1] M.M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Ann. Biochem. 72 (1976) 248-254.
2. [2] G. Chapouthier, D. Bondoux, B. Martin, C. Desforges, J.M. Launay, Genetic difference in sensitivity to β-carboline: evidence for the involvement of brain benzodiazepine receptors, Brain Res. 553 (1991) 342-346.
3. [3] G. Chapouthier, B. Martin, β-carbolines: from memory towards genetics, Eur. Bull. Cognit. Psychol. 12 (1992) 423-458.
4. [4] G. Chapouthier, P. Venault, L. Prado de Carvalho, J. Simiand, J. Rossier, Possible effects of β-carbolines on memory, Soc. Neurosci. Abstr. 10 (1984) 647.
5. [5] Y. Clément, J.-M. Launay, D. Bondoux, P. Venault, B. Martin, J. Young, P. Robel, G. Chapouthier, A mouse mutant strain highly resistant to methyl β-carboline-3-carboxylate-induced seizures, Exp. Brain Res. 110 (1996) 28-35.
6. [6] J.C. Crabbe, A. Kosobud, E.R. Young, Genetic selection for ethanol withdrawal severity: differences in replicate mouse lines, Life Sci. 33 (1983) 955-962.
7. [7] J.C. Crabbe, E.R. Young, B. Tam, A. Kosobud, J.K. Belknap, S.E. Laursen, Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity, J. Pharmacol. Exp. Ther. 239 (1986) 154-159.
8. [8] C.M. De Fiebre, R.J. Marley, L.L. Miner, N.E.C. De Fiebre, J.M. Wehner, A.C. Collins, Classical genetic analyses of responses to sedative-hypnotic drugs in crosses derived from long-sleep and short-sleep mice, Alcohol. Clin. Exp. Res. 16 (1992) 511-521.
9. [9] C. Desforges, P. Venault, R.H. Dodd, G. Chapouthier, P.L. Roubertoux, β-carboline-induced seizures in mice: genetic analysis, Pharmacol. Biochem. Behav. 34 (1989) 733-737.
10. [10] D.J. Feller, R.A. Harris, J.C. Crabbe, Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice, Eur. J. Pharmacol. 157 (1988) 147-154.
11. [11] S.E. File, D.J. Greenblatt, I.L. Martin, C.L. Brown, Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptors occupancy, Psychopharmacology 86 (1985) 137-141.
12. [12] E.J. Gallaher, L.E. Hollister, S.E. Gionet, J.C. Crabbe, Mouse lines selected for genetic differences in diazepam sensitivity, Psychopharmacology 93 (1987) 25-30.
13. [13] R.A. Harris, A.M. Allan, Genetic differences in coupling of benzodiazepine receptors to chloride channels, Brain Res. 490 (1989) 26-32.
14. [14] A.E. Kosobud, J.C. Crabbe, Ethanol withdrawal in mice bred to be genetically prone or resistant to ethanol withdrawal seizures, J. Pharmacol. Exp. Ther. 238 (1986) 170-177.
15. [15] A.E. Kosobud, J.C. Crabbe, Genetic correlations among inbred strain sensitivities to convulsions induced by nine convulsant drugs, Brain Res. 526 (1990) 8-16.
16. [16] R.J. Marley, J.M. Wehner, Correlation between the enhancement of flunitrazepam binding by GABA and seizure susceptibility in mice, Life Sci. 40 (1987) 2215-2224.
17. [17] R.J. Marley, A. Stincomb, J.M. Wehner, Further characterization of benzodiazepine receptor differences in long-sleep and short-sleep mice, Life Sci. 43 (1988) 1223-1231.
18. [18] B. Martin, C. Desforges, G. Chapouthier, Comparisons between patterns of convulsions induced by two β-carbolines in ten inbred strains of mice, Neurosci. Lett. 133 (1991) 73-76.
19. [19] B. Martin, C. Marchaland, G. Chapouthier, R. Motta, Evidence for a multigenic system controlling methyl-β-carboline-3-carboxylate (β-CCM)-induced seizures, Behav. Genet. 24 (1994) 285-297.
20. [20] G.E. McClearn, R. Kakihana, Selective breeding for ethanol sensitivity: SS and LS mice, in: G.E. McClearn, R.A. Deitrich, V.G. Erwin (Eds.), Development of Animal Models as Pharmacogenetic Tools, United States Government Printing Office, Department of Health and Human Services, Washington, DC, 1981, pp. 147-159.
21. [21] G.E. McClearn, J.R. Wilson, W. Meredith, The use of isogenic and heterogenic mouse stocks in behavioral research, in: G. Lindzey, D. Thiessen (Eds.), Contributions to Behavior-Genetic Analysis: The Mouse as a Prototype, Appleton-Century-Crofts, New York, 1970, pp. 3-22.
22. [22] D.J. Nutt, R.G. Lister, Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice, Psychopharmacology 94 (1988) 435-436.
23. [23] L. Prado de Carvalho, G. Grecksch, G. Chapouthier, J. Rossier, Anxiogenic and non-anxiogenic benzodiazepine antagonists, Nature 301 (1983) 64-66.
24. [24] L. Prado de Carvalho, G. Grecksch, E.A. Cavalheiro, R.H. Dodd, G. Chapouthier, J. Rossier, Characterization of convulsions induced by methyl-β-carboline-3-carboxylate in mice, Eur. J. Pharmacol. 103 (1984) 287-293.
25. [25] R.D. Schwartz, T.W. Seale, P. Skolnick, S.M. Paul, Differential seizure sensitivity to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/cByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding, Brain Res. 481 (1989) 169-174.
26. [26] M.M. Schweri, S.M. Paul, P. Skolnick, Strain differences in susceptibility to the convulsant actions of 3-carbomethoxy-β-carboline, Pharmacol. Biochem. Behav. 19 (1983) 951-955.
27. [27] T.W. Seale, K.A. Abla, T.H. Roderick, O.M. Rennert, J.M. Carney, Different genes specify hyporesponsiveness to seizures induced by caffeine and the benzodiazepine inverse agonist, DMCM, Pharmacol. Biochem. Behav. 27 (1987) 451-456.
28. [28] P. Venault, G. Chapouthier, L. Prado de Carvalho, J. Simiand, M. Morre, R.H. Dodd, J. Rossier, Benzodiazepine impairs and β-carboline enhances performances in learning and memory tasks, Nature 321 (1986) 864-866.
29. [29] R.E. Wimer, C.C. Wimer, C.J. Winn, N.A. Raval, N. Alameddine, A.J. Cohen, New strains of seizure-prone mice, Brain Res. 534 (1990) 94-98.
30. [30] P.T.H. Wong, W.L. Teo, Diazepam sensitive mice: differential sensitivity to the depressant and anticonvulsant effects of diazepam, Life Sci. 47 (1990) 1519-1525.
31. [31] Y.L. Yoong, P.T.H. Wong, Selective breeding of mice for differential sensitivity to diazepam, Behav. Genet. 18 (1988) 185-191.