The dose of a putative ubiquitin-specific protease affects position- effect variegation in Drosophila melanogaster

Molecular and Cellular Biology

Volumn 16, Issue 10, 1996, Pages 5717-5725

  Henchoz, Sandra ^a,b   De Rubertis, Francesco ^a   Pauli, Daniel ^a   Spierer, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN;

ARTICLE; CHROMOSOME REARRANGEMENT; DNA SEQUENCE; DROSOPHILA MELANOGASTER; GENE INSERTION; GENE MAPPING; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSGENE;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0029791553     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.10.5717     Document Type: Article

References (71)

1. Baker, R. T., J. W. Tobias, and A. Varshavsky. 1992. Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. J. Biol. Chem. 267:23364-23375.
2. Baksa, K., H. Morawietz, V. Dombradi, M. Axton, H. Taubert, G. Szabo, I. Torok, A. Udvardy, H. Gyurkovics, B. Szoor, D. Glover, G. Reuter, and J. Gausz. 1993. Mutations in the protein phosphatase 1 gene at 87B can differentially affect suppression of position-effect variegation and mitosis in Drosophila melanogaster. Genetics 135:117-125.
3. Bishop, C. P. 1992. Evidence for intrinsic differences in the formation of chromatin domains in Drosophila melanogaster. Genetics 132:1063-1069.
4. Brown, N. H., and F. C. Kafatos. 1988. Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203:425-437.
5. Busch, H. 1984. Ubiquitination of proteins. Methods Enzymol. 106:238-262.
6. Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79:13-21.
7. Cleard, F. 1993. Ph.D. thesis. University of Geneva, Geneva, Switzerland.
8. Cleard, F., M. Matsarskaia, and P. Spierer. 1995. The modifier of position-effect variegation Suvar(3)7 of Drosophila: there arc two alternative transcripts and seven scattered zinc fingers, each preceded by a tryptophan box. Nucleic Acids Res. 23:796-802.
9. Davie, J. R., and L. C. Murphy. 1994. Inhibition of transcription selectively reduces the level of ubiquitinate histone H2B in chromatin. Biochem. Biophys. Res. Commun. 203:344-350.
10. Davies, N., and G. G. Lindsey. 1994. Histone H2B (and H2A) ubiquitination allows normal histne octamer and core particle reconstitution. Biochim. Biophys. Acta 1218:187-193.
11. Dolfini, S. 1971. Karyotype polymorphism in a cell population of Drosophila melanogaster cultured in vitro. Chromosoma 33:196-208.
12. Dorn, R., V. Krauss, G. Reuter, and H. Saumweher. 1993. The enhancer of position-effect variegation of Drosophila. E(var)3-93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators. Proc. Natl. Acad. Sc. USA 90:11376-11380.
13. Dorn, R., J. Szidonya, G. Korge, M. Sehnert, H. Taubert, E. Archoukieh, B. Tschiersch, H. Morawietz, G. Wustmann, G. Hoffmann, and G. Reuter. 1993. P transposon-induced dominant enhancer mutations of position-effect variegation in Drosophila melanogaster. Genetics 133:279-290.
14. Eissenberg, J. C. 1989. Position effect variegation in Drosophila: towards a genetics of chromatin assembly. Bioessays 11:14-17.
15. Eissenberg, J. C., T. C. James, D. M. Foster-Hartnett, T. Hartnett, V. Ngan, and S. C. Elgin. 1990. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc. Natl. Acad. Sc. USA 87:9923-9927.
16. Falquet, L., N. Paquet, S. Frutiger, G. J. Hughes, K. Hoang-Van, and J. C. Jaton. 1995. cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2). FEBS Lett. 376:233-237.
17. Farkas, G., J. Gausz, M. Galloni, G. Reuter, H. Gyurkovics, and F. Karch. 1994. The Trithorax-like gene encodes the Drosophila GAGA factor. Nature (London) 371:806-808.
18. Fauvarque, M. O., and J. M. Dura. 1993. Polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila. Genes Dev. 7:1508-1520.
19. Fischer-Vize, J. A., G. M. Rubin, and R. Lehmann. 1992. The fat facets gene is required for Drosophila eye and embryo development. Development 116: 985-1000.
20. Glotzer, M. 1995. Cell cycle. The only way out of mitosis. Curr. Biol. 5:970-972.
21. Goldstein, G., M. Scheid, U. Hammerling, D. H. Schlesinger, H. D. Niall, and E. A. Boyse. 1975. Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc. Natl. Acad. Sci. USA 72:11-15.
22. Grossniklaus, U., H. J. Bellen, C. Wilson, and W. J. Gehring. 1989. P-element-mediated enhancer detection applied to the study of oogenesis in Drosophila. Development 107:189-200.
23. Hayashi, S., A. Ruddell, D. Sinclair, and T. Grigliatti. 1990. Chromosomal structure is altered by mutations that suppress or enhance position effect variegation. Chromosoma 99:391-400.
24. Henderson, D. S., S. S. Banga, T. A. Grigliatti, and J. B. Boyd. 1994. Mutagen sensitivity and suppression of position-effect variegation result from mutations in mus209, the Drosophila gene encoding PCNA. EMBO J. 13:1450-1459.
25. Hendrich, B. D., and H. F. Willard. 1995. Epigenetic regulation of gene expression: the effect of altered chromatin structure from yeast to mammals. Hum. Mol. Genet. 4:1765-1777.
26. Henikoff, S. 1990. Position-effect variegation after 60 years. Trends Genet. 6:422-426.
27. Hochstrasser, M. 1995. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol. 7:215-223.
28. Huang, Y., R. T. Baker, and J. A. Fischer-Vize. 1995. Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270:1828-1831.
29. Karpen, G. H., and A. C. Spradling. 1990. Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila. Cell 63:97-107.
30. Kornberg, R. D., and Y. Lorch. 1995. Interplay between chromatin structure and transcription. Curr. Opin. Cell Biol. 7:371-375.
31. Laman, H., D. Balderes, and D. Shore. 1995. Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:3608-3617.
32. Levinger, L., and A. Varshavsky. 1982. Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome. Cell 28:375-385.
33. Lindsley, D. L., and G. G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press, Inc., New York.
34. Locke, J., M. A. Kotarski, and K. D. Tartof. 1988. Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect. Genetics 120:181-198.
35. Maniatis, T., R. C. Hardison, E. Lacy, J. Lauer, C. O'Connell, D. Quon, G. K. Sim, and A. Efstratiadis. 1978. The isolation of structural genes from libraries of eucaryotic DNA. Cell 15:687-701.
36. Moazed, D., and A. S. Johnson. Personal communication.
37. Moehrle, A., and R. Paro. 1994. Spreading the silence: epigenetic transcriptional regulation during Drosophila development. Dev. Genet. 15:478-484.
38. Monaco, J., and D. Nandi. 1995. The genetics of proteasomes and antigen processing. Annu. Rev. Genet. 29:729-754.
39. Nakamura, T., J. Hillova, R. Mariage-Samson, M. Onno, K. Huebner, L. A. Cannizzaro, L. Boghosian-Sell, C. M. Croce, and M. Hill. 1992. A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells. Oncogene 7:733-741.
40. Palombella, V. J., O. J. Rando, A. L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 78:773-785.
41. Papa, F. R., and M. Hochstrasser. 1993. The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature (London) 366:313-319.
42. Paro, R., and D. S. Hogness. 1991. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl. Acad. Sci. USA 88:263-267.
43. Pickart, C. M., and I. A. Rose. 1986. Mechanism of ubiquitin carboxyl-terminal hydrolase. Borohydride and hydroxylamine inactivate in the presence of ubiquitin. J. Biol. Chem. 261:10210-10217.
44. Pirrotta, V. 1986. Cloning Drosophila genes, p. 83-109. In D. B. Roberts (ed.), Drosophila, a practical approach. IRL Press, Oxford.
45. Ramos, R. G., G. L. Igloi, B. Lichte, U. Baumann, D. Maier, T. Schneider, J. H. Brandstatter, A. Frohlich, and K. F. Fischbach. 1993. The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein. Genes Dev. 7:2533-2547.
46. Reuter, G., M. Giarre, J. Farah, J. Gausz, A. Spierer, and P. Spierer. 1990. Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-linger protein. Nature (London) 344:219-223.
47. Reuter, G., and P. Spierer. 1992. Position effect variegation and chromatin proteins. Bioessays 14:605-612.
48. Reuter, G., W. Werner, and H. J. Hoffmann. 1982. Mutants affecting position-effect heterochromatinization in Drosophila melanogaster. Chromosoma 85:539-551.
49. Reuter, G., and I. Wolff. 1981. Isolation of dominant suppressor mutations for position-effect variegation in Drosophila melanogaster. Mol. Gen. Genet. 182:516-519.
50. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
51. Saville, K. J., and J. M. Belote. 1993. Identification of an essential gene, I(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit. Proc. Natl. Acad. Sci. USA 90:8842-8846.
52. Schneuwly, S., A. Kuriowa, P. Baumgartner, and W. J. Gehring. 1986. Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster. EMBO J. 4:733-739.
53. Seifert, H. S., E. Y. Chen, M. So, and F. Heffron. 1986. Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 83:735-739.
54. Seufert, W., B. Futcher, and S. Jentsch. 1995. Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature (London) 373:78-81.
55. Seum, C., A. Spierer, D. Pauli, J. Szidonya, G. Reuter, and P. Spierer. 1996. Position-effect variegation in Drosophila depends on dose of the gene encoding the E2F transcriptional activator and cell cycle regulator. Development 122:1949-1956.
56. Siegelman, M., M. W. Bond, W. M. Gallatin, T. St. John, H. T. Smith, V. A. Fried, and I. L. Weissman. 1986. Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. Science 231:823-829.
57. Soeller, W. C., C. E. Oh, and T. B. Kornberg. 1993. Isolation of cDNAs encoding the Drosophila GAGA transcription factor. Mol. Cell. Biol. 13: 7961-7970.
58. Southern, E. M. 1975. Detection of sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503-517.
59. Spierer, P., A. Spierer, W. Bender, and D. S. Hogness. 1983. Molecular mapping of genetic and chromomeric units in Drosophila melanogaster. J. Mol. Biol. 168:35-50.
60. Spradling, A. C. 1986. P element-mediated transformation, p. 175-196. In D. B. Roberts (ed.), Drosophila, a practical approach. IRL Press, Oxford.
61. Tamkun, J. W., R. Deuring, M. P. Scott, M. Kissinger, A. M. Pattatucci, T. C. Kaufman, and J. A. Kennison. 1992. brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SW12. Cell 68:561-572.
62. Tartof, K. D., C. Bishop, M. Jones, C. A. Hobbs, and J. Locke. 1989. Towards an understanding of position effect variegation. Dev. Genet. 10:162-176.
63. Tartof, K. D., C. Hobbs, and M. Jones. 1984. A structural basis for variegating position effects. Cell 37:869-878.
64. Tautz, D., and C. Pfeifle. 1989. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98:81-85.
65. Tschiersch, B., A. Hofmann, V. Krauss, R. Dorn, G. Korge, and G. Reuter. 1994. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13:3822-3831.
66. Tsukiyama, T., C. Daniel, J. Tamkun, and C. Wu. 1995. ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor. Cell 83:1021-1026.
67. Vijay-Kumar, S., C. E. Bugs, K. D. Wilkinson, R. D. Vierstra, P. M. Hatfield, and W. J. Cook. 1987. Comparison of the three-dimensional structures of human, yeast, and oat ubiquitin. J. Biol. Chem. 262:6396-6399.
68. Wilkinson, K. D., V. L. Tashayev, L. B. O'Connor, C. N. Larsen, E. Kasperek, and C. M. Pickart. 1995. Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T. Biochemistry 34: 14535-14546.
69. Xiao, W., T. Fontanie, and M. Tang. 1994. UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product. Yeast 10:1497-1502.
70. Yarden, Y., J. A. Escobedo, W. J. Kuang, T. L. Yang-Feng, T. O. Daniel, P. M. Tremble, E. Y. Chen, M. E. Ando, R. N. Harkins, U. Francke, V. A. Fried, A. Ullrich, and L. T. Williams. 1986. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature (London) 323:226-232.
71. Zhang, N., K. Wilkinson, and M. Bownes. 1993. Cloning and analysis of expression of a ubiquitin carboxyl terminal hydrolase expressed during oogenesis in Drosophila melanogaster. Dev. Biol. 157:214-223.