Cellular alloreactivity of human cord blood cells detected by T-cell frequency analysis and a human skin explant model

Transplantation

Volumn 66, Issue 7, 1998, Pages 903-909

  Wang, Xiao N ^a   Sviland, Lisbet ^a   Ademokun, Adebo J ^a   Dunn, Janice ^a   Cavanagh, Gary ^a   Proctor, Stephen J ^a   Dickinson, Anne M ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN;

ADULT; ALLOIMMUNITY; ARTICLE; BLOOD CELL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EXPLANT; FREQUENCY ANALYSIS; GRAFT VERSUS HOST REACTION; HELPER CELL; HLA MATCHING; HUMAN; HUMAN CELL; HUMAN TISSUE; MODEL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROLYMPHOCYTE; SKIN; T LYMPHOCYTE; UMBILICAL CORD BLOOD;

BLOOD CELLS; CULTURE TECHNIQUES; FETAL BLOOD; HISTOCOMPATIBILITY; HLA ANTIGENS; HUMANS; INDICATOR DILUTION TECHNIQUES; ISOANTIGENS; LYMPHOCYTE COUNT; MONOCYTES; SKIN; STEM CELLS; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0032532201     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199810150-00015     Document Type: Article

References (38)

1. Broxmeyer HE, Douglas GW, Hangoc G, et al. Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc Natl Acad Sci USA 1989; 86: 3828.
2. Wagner JE, Kernan NA, Steinbuch M, et al. Allogeneic sibling umbilical cord blood transplantation in children with malignant and non-malignant disease. Lancet 1995; 346: 214.
3. Kurtzberg J, Laughlin M, Graham M, et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 1996; 335: 157.
4. Apperley JF. Umbilical cord blood progenitor cell transplantation. Bone Marrow Transplantation 1994; 14: 187.
5. Broxmeyer HE. Questions to be answered regarding umbilical cord blood hematopoietic stem and progenitor cells and their uses in transplantation. Transfusion 1995; 35: 694.
6. Ademokun JA, Chapman C, Dunn J, et al. Umbilical cord blood collection and separation for haematopoietic progenitor cell banking. Bone Marrow Transplant 1997; 19: 1023.
7. Dickinson AM, Sviland L, Carey PJ, et al. Skin explant culture as a model for cutaneous graft versus host disease in humans. Bone Marrow Transplant 1988; 3: 323.
8. Sviland L, Dickinson AM, Carey PJ, et al. An in vitro predictive test for clinical graft versus host disease in allogeneic bone marrow transplant recipients. Bone Marrow Transplant 1990; 5: 105.
9. Lerner KG, Kao GF, Storb R, et al. Histopathology of graft versus host reaction (GVHR) in human recipients of marrow from HLA-matched sibling donors. Transplantation 1974; 18: 295.
10. Dickinson AM, Sviland L, Hamilton PJ, et al. Cytokine involvement in predicting clinical graft-versus-host disease in allogeneic bone marrow transplant recipients. Bone Marrow Transplant 1994; 13: 65.
11. Wang XN, Proctor SJ, Dickinson AM. Frequency analysis of recipient-reactive helper and cytotoxic T lymphocyte precursors using a combined single limiting dilution assay. Transplant Immunol 1996; 4: 247.
12. Strijbosch LWG, Buurman WA, Does RJMM, et al. Limiting dilution assays: experimental design and statistical analysis. J Immunol Methods 1987; 97: 133.
13. Strijbosch LWG, Does RJMM, Buurman WA. Computer aided design and evaluation of limiting and serial dilution experiments. Int J Biomed Comput 1988; 23: 279.
14. Gratwohl A, Hermans J, Baldomero H. Blood and marrow transplantation activity in Europe 1995. Bone Marrow Transplant 1997; 19: 407.
15. Wagner JE, Rosenthal J, Sweetman R, et al. Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease. Blood 1996; 88: 795.
16. Kurtzberg J, Graham M, Casey J, et al. The use of umbilical cord blood in mismatched related and unrelated hemopoietic stem cell transplantation. Blood Cells 1994; 20: 275.
17. Eisner MD, August CS. Impact of donor and recipient characteristics on the development of acute and chronic graft-versus-host disease following pediatric bone marrow transplantation. Bone Marrow Transplant 1995; 15: 663.
18. Speiser DE, Loliger CC, Siren MK, et al. Pretransplant cytotoxic donor T cell activity specific to patient HLA class I antigens correlating with mortality after unrelated BMT. Br J Haematol 1996; 93: 935.
19. Schwarer A, Jiang YZ, Deacock S, et al. Comparison of helper and cytotoxic antirecipient T cell frequencies in unrelated bone marrow transplantation. Transplantation 1994; 58: 1198.
20. Kaminski E, Sharrock C, Hows J, et al. Frequency analysis of cytotoxic T lymphocyte precursors: possible relevance to HLA-matched unrelated donor bone marrow transplantation. Bone Marrow Transplant 1988; 3: 149.
21. Spencer A, Brookes P, Kaminski E, et al. Cytotoxic T lymphocyte precursor frequency analysis in bone marrow transplantation with volunteer unrelated donors: value in donor selection. Transplantation 1995; 59: 1302.
22. Theobald M, Nierle T, Bunjes D, et al. Host-specific interleukin-2-secreting donor T-cell precursors as predictors of acute graft-versus-host disease in bone marrow transplantation between HLA-identical siblings. N Engl J Med 1992; 327: 1613.
23. Schwarer AP, Jiang YZ, Brookes PA, et al. Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation. Lancet 1993; 341: 203.
24. Kaminski E, Hows J, Man S, et al. Prediction of graft versus host disease by frequency analysis of cytotoxic T cells after unrelated donor bone marrow transplantation. Transplantation 1989; 48: 608.
25. Fairfax CA, Borzy MS. Interleukin 2 production, proliferative response, and receptor expression by cord blood mononuclear cells. J Clin Lab Immunol 1988; 27: 63.
26. Harris DT, Schumacher MJ, Locascio J, et al. Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes. Immunology 1992; 89: 10006.
27. Roncarolo MG, Bigler M, Ciuti E, et al. Immune responses by cord blood cells. Blood Cells 1994; 20: 573.
28. Keever CA, Abu-Hajir M, Graf W, et al. Characterization of the alloreactivity and anti-leukemia reactivity of cord blood mononuclear cells. Bone Marrow Transplant 1995; 15: 407.
29. Deacock SJ, Schwarer AP, Bridge J, et al. Evidence that umbilical cord blood contains a higher frequency of HLA class II specific alloreactive T cells than adult peripheral blood. Transplantation 1992; 53: 1128.
30. Roelen DL, van Bree SPMJ, van Beelen E, et al. Cytotoxic T lymphocytes against HLA-B antigens are less naive than cytotoxic T lymphocytes against HLA-A antigens. Transplantation 1994; 57: 446.
31. Potolicchio I, Brookes PA, Madrigal A, et al. HLA-DPB1 mismatch at position 69 is associated with high helper T lymphocyte precursor frequencies in unrelated bone marrow transplant pairs. Transplantation 1996; 62: 1347.
32. Harris DT, Locascio J, Besencon FJ. Analysis of the alloreactive capacity of human umbilical cord blood: implications for graft-versus-host disease. Bone Marrow Transplant 1994; 14: 545.
33. Breur-Vriesendorp B, Vingerhoed J, van Twuyver E, et al. Frequency analysis of HLA-specific cytotoxic T lymphocyte precursors in humans. Transplantation 1991; 51: 1096.
34. Berthou C, Legros-Maida S, Soulie A, et al. Cord blood T lymphocytes lack constitutive perform expression in contrast to adult peripheral blood T lymphocytes. Blood 1995; 85: 1540.
35. Beck R, Lam-Po-Tang, PR. Comparison of cord blood and adult blood lymphocyte normal ranges: a possible explanation for decreased severity of graft versus host disease after cord blood transplantation. Immunol Cell Biol 1994; 72: 440.
36. Han P, Hodge G, Story C, et al. Phenotypic analysis of functional T-lymphocyte subtypes and natural killer cells in human cord blood: relevance to umbilical cord blood transplantation. Br J Haematol 1995; 89: 733.
37. Roncarolo MG. The role of interleukin-10 in transplantation and GVHD. In: Ferrara JLM, Deeg HJ, Burakoff SJ, eds. Graft-vs-host disease. New York: Marcel Dekker Inc., 1996; 694.
38. Sharrock CEM, Man S, Wanachiwanawin W. et al. Analysis of the alloreactive T cell repertoire in man. I. Differences in precursor frequency for cytotoxic T cell responses against allogeneic MHC molecules in unrelated individuals. Transplantation 1987; 43: 699.