HLA-DPB1 mismatch at position 69 is associated with high helper T lymphocyte precursor frequencies in unrelated bone marrow transplant pairs

Transplantation

Volumn 62, Issue 9, 1996, Pages 1347-1352

  Potolicchio, Ilaria ^a,b   Brookes, Paul A ^c   Madrigal, Alejandro ^c   Lechler, Robert I ^c   Sorrentino, Rosa ^a,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA B ANTIGEN; HLA DP ANTIGEN; HLA DR ANTIGEN;

ALLOIMMUNITY; ARTICLE; BONE MARROW TRANSPLANTATION; CYTOTOXIC T LYMPHOCYTE; GENETIC POLYMORPHISM; GENOTYPE; GRAFT VERSUS HOST REACTION; HELPER CELL; HLA MATCHING; HUMAN; HUMAN CELL; ISOELECTRIC FOCUSING; MIXED LYMPHOCYTE CULTURE; PRIORITY JOURNAL; PROLYMPHOCYTE;

BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; HISTOCOMPATIBILITY TESTING; HLA-DP ANTIGENS; HUMANS; POLYMORPHISM, GENETIC; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0030445609     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199611150-00029     Document Type: Article

References (30)

1. McGlave PB, Beatty PG, Ash R, Hows JM. Therapy for chronic myelogenous leukemia with unrelated donor bone marrow transplantation: results in 102 cases. Blood 1990; 75: 1728.
2. Beatty PG, Hansen JA, Longton GM, et al. Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies. Transplantation 1991; 51: 443.
3. Beatty PG, Clift RA, Mickelson EM, et al. Marrow transplantation from related donors other than HLA-identical siblings. N Engl J Med 1985; 313: 765.
4. Ash RC, Casper JT, Chitambar CR, et al. Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. N Engl J Med 1990; 322: 485.
5. Hansen JA, Anasetti C, Beatty GP, et al. Treatment of leukemia by marrow transplantation from HLA incompatible donors: effect of HLA-disparity on GVHD, relapse and survival. Bone Marrow Transplant 1990; 6: 108.
6. Anasetti C, Beatty PG, Storb R, et al. Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma. Hum Immunol 1990; 29: 79.
7. Schwarer AP, Jiang YZ, Deacock S, et al. Comparison of helper and cytotoxic antirecipient T cell frequencies in unrelated bone marrow transplantation. Transplantation 1994; 58: 1198.
8. Spencer A, Brookes PA, Kaminski E, et al. Cytotoxic T lymphocyte precursor frequency analyses in bone marrow transplantation with volunteer unrelated donors. Transplantation 1995; 59: 1302.
9. Spencer A, Szydlo RM, Brookes PA, et al. Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient. Blood 1995; 86: 3590.
10. D'Amato M, Sorrentino R. A simple and economical DRB1 typing procedure combining group specific amplification, DNA hetero-duplex and enzyme restriction analysis. Tissue Antigens 1994; 43: 295.
11. D'Amato M, Sorrentino R. Short insertions in the partner strands greatly enhance the discriminating power of DNA heteroduplex analysis: resolution of HLA-DQB1 polymorphisms. Nucleic Acids Res 1995; 23: 2078.
12. Sorrentino R, Potolicchio I, Ferrara GB, Tosi R. A new approach to HLA-DPB1 typing with allele-specific amplification and enzyme restriction. Immunogenetics 1992; 36: 248.
13. Kaminski E, Hows JM, Goldman JM, et al. Optimizing a limiting dilution culture system for quantitating frequencies of alloreactive cytotoxic T lymphocyte precursors. Cell Immunol 1991; 137: 88.
14. Fazekas de St. Groth S. The evaluation of limiting dilution assays. J Immunol Methods 1982; 49: R11.
15. Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Assoc 1976; 53: 457.
16. Brown JH, Jardetzky TS, Gorga JC, et al. 3-Dimensional structure of the human class-II histocompatibility antigens HLA-DR1. Nature 1993; 364: 33.
17. Sell TW, Eckels DD. Primary mixed lymphocyte responses to HLA-DP. Hum Immunol 1990; 29: 23.
18. Cesbron A, Moreau P, Milpied N, Harousseau JL, Muller JW, Bignon JF. Crucial role of the third and fourth hypervariable regions of HLA-DPB1 allelic sequences in the mixed lymphocyte reaction. Hum Immunol 1992; 33: 202.
19. Olerup O, Moller E, Persson U. HLA-DP incompatibilities induce proliferation in primary mixed lymphocyte culture in HLA-A, B, C, DR and DQ compatible individuals: implications for allogeneic bone marrow transplantation. Tissue Antigens 1990; 36: 1940.
20. Al Daccak R, Loiseau P, Soulie A, et al. HLA-DP genotyping in HLA-A, B and DR identical intrafamilial bone marrow transplantation. Leukemia 1990; 4: 222.
21. De Gast GC, Mickelson EM, Beatty PG, et al. Mixed lymphocyte culture reactivity and graft-versus-host disease in HLA-identical marrow transplantation for leukemia. Bone Marrow Transplant 1992; 9: 87.
22. Nomura N, Ota M, Kato S, Inoko H, Tsuji K. Severe acute graft-versus-host disease by HLA-DPB1 disparity in recombinant family of bone marrow transplantation between serologically HLA-Identical siblings: an application of the polymerase chain reaction-restriction fragment length polymorphism method. Hum Immunol 1991; 32: 261.
23. Kato Y, Mitsuishi Y, Cecka M, et al. HLA-DP incompatibilities and severe graft-versus-host disease in unrelated bone marrow transplants. Transplantation 1991; 52: 374.
24. Gaschet J, Mahe B, Milpied N, et al. Specificity of T cells invading the skin during acute graft-versus-host disease after semi-allogeneic bone marrow transplantation. J Clin Invest 1993; 91: 12.
25. Petersdorff EW, Smith AG, Mickelson EM, et al. The role of HLA-DPB1 disparity in the development of acute graft-versus-host disease following unrelated donor marrow transplantation. Blood 1993; 81: 1923.
26. Lundin KEA, Scott H, Hansen T, et al. Gliadin-specific, HLA-DQ (α1*0501,β1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med 1993; 178: 187.
27. Begovich AB, Bugawan TL, Nepom BS, et al. A specific HLA DP β allele is associated with pauciarticular juvenile arthritis but not adult rheumatoid arthritis. Proc Natl Acad Sci USA 1989; 86: 9489.
28. Bugawan TL, Angelini G, Larrick J, et al. A combination of a particular HLA DP β allele and HLA DQ heterodimer confers susceptibility to coeliac disease. Nature 1989; 339: 470.
29. Richeldi L, Sorrentino R, Saltini C. HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science 1993; 262: 242.
30. Sinigaglia F, Hammer J. Motifs and supermotifs for MHC class II binding peptides. J Exp Med 1995; 181: 449.