Regulation of human IP-10 gene expression in astrocytoma cells by inflammatory cytokines

Journal of Neuroscience Research

Volumn 54, Issue 2, 1998, Pages 169-180

  Majumder, Sarmila ^a,b   Zhou, Lucy Z H ^a   Chaturvedi, Priya ^a,c   Babcock, Gerald ^a   Aras, Sumer ^a,d   Ransohoff, Richard M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ANKARA UNIVERSITY   (Turkey)

Author keywords

Astrocytes; Chemokines; Gene transcription; Interferons; TNF

Indexed keywords

GAMMA INTERFERON; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTROCYTOMA CELL; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTOMA; BINDING SITES; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; INTERFERON TYPE II; MICE; NF-KAPPA B; RATS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032532023     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19981015)54:2<169::AID-JNR5>3.0.CO;2-C     Document Type: Article

References (32)

1. Aiyar A, Leis J (1993): Modification of the megaprimer method of PCR mutagenesis: Improved amplification of the final product. Biotechniques 14:366-369.
2. Arenberg DA, Kunkel SL, Polverini PJ, Morris SB, Burdick MD, Glass MC, Taub DT, Iannettoni MD, Whyte RI, Strieter RM (1996): Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases. J Exp Med 184:981-992.
3. Asensio VC, Campbell IL (1997): Chemokine gene expression in the brains of mice with lymphocytic choriomeningitis. J Virol 71:7832-7840.
4. Ausbel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1987): "Current Protocols in Molecular Biology." New York: John Wiley & Sons.
5. Chomczynski P, Sacchi N (1987): Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 62:156-159.
6. Devajyothi C, Kalvakolanu I, Babcock GT, Vasavada H, Howe PH, Ransohoff RM (1993): Inhibition of interferon-gamma induced gene transcription by Interferon beta and type beta 1 transforming growth factor in human astrocytoma cells. J Biol Chem 268:18794-18800.
7. Dignam JD, Lebovitz RM, Roeder RG (1983): Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
8. Estes ML, Ransohoff RM, McMahon JT, Jacobs BS, Barna BP (1990): Characterization of adult human astrocytes derived from explant culture. J Neurosci Res 27:697-705.
9. Freter R, Alberta J, Hwsang G, Wrentomore A, Stiles C (1996): Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-κB and a 90-kDa phosphoprotein coactivator. J Biol Chem 271:17417-17424.
10. Glabinski A, Tani M, Aras S, Stoler M, Tuohy V, Ransohoff R (1995): Regulation and function of central nervous system chemokines. lnt J Dev Neurosci 13:153-165.
11. Glabinski A, Tani M, Tuohy VK, Tuthill R, Ransohoff RM (1996): Central nervous system chemokine gene expression follows leukocyte entry in acute murine experimental autoimmune encephalomyelitis. Brain Behav Immunol 9:315-330.
12. Glabinski A, Tani M, Strieter R, Tuohy V, Ransohoff R (1997): Synchronous synthesis of α-and β-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of experimental autoimmune encephalomyelitis. Am J Pathol 150:617-630.
13. Johns LD, Babcock G, Green D, Freedman M, Sriram S, Ransohoff RM (1992): Transforming growth factor-beta 1 differentially regulates proliferation and MHC class-II antigen expression in forebrain and brainstem astrocyte primary cultures. Brain Res 585:229-236.
14. Kessler DS, Levy DE, Darnell J.E. J (1988): Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc Natl Acad Sci USA 85:8521-8525.
15. Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B (1996): Chemokine receptor specific for IP1O and mig: Structure, function, and expression in activated T-lymphocytes [see comments]. J Exp Med 184:963-969.
16. Luster AD, Leder P (1993): IP-1O, a CXC chemokine, elicits a potent thymus-dependent antitumor response in vivo. J Exp Med. 178:1057-1065.
17. Luster AD, Unkeless JC, Ravetch JV (1985): Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 315:672-676.
18. Majumder S, Zhou Z-HL, Ransohoff R (1996): Transcriptional regulation of chemokine gene expression in astrocytes. J Neurosci Res 45:758-769.
19. Nazar AS, Cheng G, Shin HS, Brothers PN, Dhib-Jalbut S, Shin ML, Vanguri P (1997): Induction of IP-10 chemokine promoter by measles virus: Comparison with interferon-gamma shows the use of the same response element but with differential DNA-protein binding profiles. J Neuroimmunol 77:116-127.
20. Ohmori Y, Hamilton TA (1995): The Interferon-stimulated response element and a κB site mediate synergistic induction of murine IP-10 gene transcription by IFN-γ and TNFα. J Immunol 154:5235-5244.
21. Ransohoff R (1997): Chemokines in neurological disease models: correlation between chemokine expression patterns and inflammatory pathology. J Leukocyte Biol 62:645-652.
22. Ransohoff R, Devajyothi C, Estes M, Babcock G, Rudick R, Frohman E, Barna B (1991): Interferon-β specifically inhibits interferon-γ-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line. J Neuroimmunol 33:103-112.
23. Ransohoff R, Hamilton T, Tani M, Stoler M, Shick H, Major J, Estes M, Thomas D, Tuohy V (1993): Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 7:592-602.
24. Ransohoff R, Glabinski A, Tani M (1996): Chemokines in immunemediated inflammation of the central nervous system. Cytokine Growth Factor Rev 7:35-46.
25. Sgadari C, Angiolillo AL, Cherney BW, Pike SE, Farber JM, Koniaris LG, Vanguri P, Burd PR, Sheikh N, Gupta G, Teruya-Feldstein J, Tosato G (1996): Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo. Proc Natl Acad Sci USA 93:13791-13796.
26. Sgadari C, Farber JM, Angiolillo AL, Liao F, Teruya-Feldstein J, Burd PR, Yao L, Gupta G, Kanegane C, Tosato G (1997): Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo. Blood 89:2635-2643.
27. Sun D, Hu X, Liu X, Whitaker JN, Walker WS (1997): Expression of chemokine genes in rat glial cells: The effect of myelin basic protein-reactive encephalitogenic T cells. J Neurosci Res 48:192-200.
28. Tani M, Ransohoff RM (1994): Do Chemokines mediate inflammatory cell invasion of the central nervous system parenchyma? Brain Pathol 4:135-144.
29. Tani M, Glabinski AR, Tuohy VK, Stoler MH, Estes ML, Ransohoff RM (1996): In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis. Am J Pathol 148:889-896.
30. Taub D, Lloyd A, Conlon K, Wang J, Ortoldo J, Harada A, Matsushima K, Kelvin D, Oppenheim J (1993): Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 177:1809-1814.
31. Vanguri P, Farber JM (1994): IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-Aa, in astrocytes and microglia. J Immunol 152:1411-1418.
32. Wojcik WJ, Swoveland P, Zhang X, Vanguri P (1996): Chronic intrathecal infusion of phosphorothioate or phosphodiester antisense oligonucleotides against cytokine responsive gene-2/ IP-10 in experimental allergic encephalomyelitis of lewis rat. J Pharmacol Exp Ther 278:404-410.