Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex: Identification of important amino acid residues

Biochemical Journal

Volumn 334, Issue 3, 1998, Pages 703-711

  Jackson, John C ^a,c   Vinluan, Christine C ^a   Dragland, Carol J ^a   Sundararajan, Vijayayakumar ^a,d   Yan, Bing ^a   Gounarides, John S ^a   Nirmala, Nanguneri R ^a   Topiol, Sid ^a   Ramage, Paul ^b   Blume, John E ^a,e   Aicher, Thomas D ^a   Bell, Philip A ^a   Mann, William R ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Pierce Chemical Company   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

^e Metabolex Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ADENOSINE TRIPHOSPHATE; ISOLEUCINE; PHENYLALANINE; PYRUVATE DEHYDROGENASE COMPLEX;

ARTICLE; BIOPHYSICS; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

ACETYLTRANSFERASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CATALYTIC DOMAIN; CLONING, MOLECULAR; DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHORYLATION; PROTEIN CONFORMATION; PYRUVATE DEHYDROGENASE COMPLEX; RATS; RECOMBINANT PROTEINS; SWINE;

ANIMALIA;

EID: 0032530887     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3340703     Document Type: Article

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