A loop deletion in the plant acetohydroxy acid isomeroreductase homodimer generates an active monomer with reduced stability and altered magnesium affinity

Biochemistry

Volumn 37, Issue 37, 1998, Pages 12753-12760

  Wessel, Peter M ^a   Biou, Valérie ^b   Douce, Roland ^a   Dumas, Renaud ^a  

^a SANOFI   (France)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

KETOL ACID REDUCTOISOMERASE; MONOMER; OXIDOREDUCTASE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ARTICLE; BINDING SITE; CATALYSIS; DELETION MUTANT; DIMERIZATION; ENZYME MECHANISM; FLUORESCENCE; GEL FILTRATION; MOLECULAR STABILITY; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS;

ALCOHOL OXIDOREDUCTASES; BINDING SITES; DIMERIZATION; ENZYME ACTIVATION; ENZYME STABILITY; KETOL-ACID REDUCTOISOMERASE; KINETICS; MAGNESIUM; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; RECOMBINANT PROTEINS; SERINE; SPINACIA OLERACEA; THERMODYNAMICS;

EID: 0032530512     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980411g     Document Type: Article

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