Increased concentrations of methylated 6-mercaptopurine metabolites and 6-thioguanine nucleotides in human leukemic cells in vitro by methotrexate

Biochemical Pharmacology

Volumn 55, Issue 10, 1998, Pages 1641-1646

  Giverhaug, Trude ^a   Loennechen, Thrina ^a   Aarbakke, Jarle ^a  

^a Inst Med Biol Inst Pharm U   (Norway)

Author keywords

Acute lymphoblastic leukemia; Antimetabolites; Drug interaction

Indexed keywords

6 THIOGUANINE NUCLEOTIDE; ANTIMETABOLITE; FOLIC ACID ANTAGONIST; MERCAPTOPURINE; METHOTREXATE; METHYLMERCAPTOPURINE MONOPHOSPHATE; THIOPURINE METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOBLAST; CANCER CELL CULTURE; CELL LEVEL; DRUG ACTIVITY; DRUG METABOLISM; DRUG UPTAKE; HUMAN; HUMAN CELL; HYBRID CELL; PRIORITY JOURNAL; PROMYELOCYTE; T LYMPHOBLAST;

6-MERCAPTOPURINE; CULTURE MEDIA; GUANINE NUCLEOTIDES; HUMANS; METHOTREXATE; METHYLATION; THIOGUANINE; TUMOR CELLS, CULTURED;

EID: 0032525033     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00681-3     Document Type: Article

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