메뉴 건너뛰기




Volumn 40, Issue 4, 1997, Pages 367-370

Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo

Author keywords

6 Thioguanine nucleotide; Interaction; Metabolism; Methylmercaptopurine

Indexed keywords

DRUG METABOLITE; MERCAPTOPURINE; METHOTREXATE; THIOPURINE METHYLTRANSFERASE;

EID: 0030952175     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050672     Document Type: Article
Times cited : (7)

References (21)
  • 2
    • 0015009229 scopus 로고
    • Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine
    • Bennett LL, Allan PW (1971) Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine. Cancer Res 31: 152
    • (1971) Cancer Res , vol.31 , pp. 152
    • Bennett, L.L.1    Allan, P.W.2
  • 9
    • 0023588197 scopus 로고
    • Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells
    • Lennard L (1987) Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells. J Cromatogr 423: 169
    • (1987) J Cromatogr , vol.423 , pp. 169
    • Lennard, L.1
  • 10
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute lymplioblastic leukaemia
    • Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM (1990) Genetic variation in response to 6-mercaptopurine for childhood acute lymplioblastic leukaemia. Lancet 336: 229
    • (1990) Lancet , vol.336 , pp. 229
    • Lennard, L.1    Lilleyman, J.S.2    Van Loon, J.3    Weinshilboum, R.M.4
  • 11
    • 0021348004 scopus 로고
    • Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin
    • Lewis AS, Murphy L, McCalla C, Fleary M, Purcell S (1984) Inhibition of mammalian xanthine oxidase by folate compounds and amethopterin. J Biol Chem 259: 12
    • (1984) J Biol Chem , vol.259 , pp. 12
    • Lewis, A.S.1    Murphy, L.2    McCalla, C.3    Fleary, M.4    Purcell, S.5
  • 12
    • 0026550162 scopus 로고
    • On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro
    • Liliemark J, Pettersson B, Peterson C (1992) On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro. Leukemia Res 16: 275
    • (1992) Leukemia Res , vol.16 , pp. 275
    • Liliemark, J.1    Pettersson, B.2    Peterson, C.3
  • 13
    • 0028930908 scopus 로고
    • Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemia blasts from children with acute lymphoblastic leukemia
    • McLeod HL, Relling MV, Liu Q, Pui C-H, Evans WE (1995) Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemia blasts from children with acute lymphoblastic leukemia. Blood 85: 1897
    • (1995) Blood , vol.85 , pp. 1897
    • McLeod, H.L.1    Relling, M.V.2    Liu, Q.3    Pui, C.-H.4    Evans, W.E.5
  • 14
    • 0015410601 scopus 로고
    • Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in Sarcoma 180 cells
    • Nelson JA, Parks RE (1972) Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in Sarcoma 180 cells. Cancer Res 32: 2034
    • (1972) Cancer Res , vol.32 , pp. 2034
    • Nelson, J.A.1    Parks, R.E.2
  • 15
    • 0026732582 scopus 로고
    • Antifolates induce inhibition of amido phosphoribosyl-transferase in leukemia cells
    • Sant ME, Lyons SD, Phillips L, Christopherson RI (1992) Antifolates induce inhibition of amido phosphoribosyl-transferase in leukemia cells. J Biol Chem 267: 11038
    • (1992) J Biol Chem , vol.267 , pp. 11038
    • Sant, M.E.1    Lyons, S.D.2    Phillips, L.3    Christopherson, R.I.4
  • 16
    • 0026907122 scopus 로고
    • Human liver thiopurine methyltransferase pharmacogenetics: Biochemical properties, liver-erythrocyte correlation and presence of isozymes
    • Szumlanski CL, Honchel R, Scott MC, Weinshilboum RM (1992) Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes. Pharmacogenetics 2: 148
    • (1992) Pharmacogenetics , vol.2 , pp. 148
    • Szumlanski, C.L.1    Honchel, R.2    Scott, M.C.3    Weinshilboum, R.M.4
  • 17
    • 0019366906 scopus 로고
    • Rat thiopurine methyltransferase assay procedure, developmental changes and strain variation
    • Walker RC, Woodson LC, Weinshilboum RM (1981) Rat thiopurine methyltransferase assay procedure, developmental changes and strain variation. Biochem Pharmacol 30: 115
    • (1981) Biochem Pharmacol , vol.30 , pp. 115
    • Walker, R.C.1    Woodson, L.C.2    Weinshilboum, R.M.3
  • 18
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL (1980) Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 32: 651
    • (1980) Am J Hum Genet , vol.32 , pp. 651
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 19
    • 0017880983 scopus 로고
    • Human erythrocyte thiopurine methyltransferase: Radiochemical microassay and biochemical properties
    • Weinshilboum RM, Raymond FA, Pazmiño PA (1978) Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 85: 323
    • (1978) Clin Chim Acta , vol.85 , pp. 323
    • Weinshilboum, R.M.1    Raymond, F.A.2    Pazmiño, P.A.3
  • 20
    • 0018101629 scopus 로고
    • Consequences of inhibition of purine biosynthesis de novo by 6-methylmercaptopurine ribonucleoside in cultured lymphoma L5178Y cells
    • Woods RA, Henderson RM, Henderson JF (1978) Consequences of inhibition of purine biosynthesis de novo by 6-methylmercaptopurine ribonucleoside in cultured lymphoma L5178Y cells. Eur J Cancer 14: 765
    • (1978) Eur J Cancer , vol.14 , pp. 765
    • Woods, R.A.1    Henderson, R.M.2    Henderson, J.F.3
  • 21
    • 0019956940 scopus 로고
    • Pharmacogenetics of human thiopurine methyltransferase: Kidney-erythrocyte correlation and immunolitration studies
    • Woodson LC, Dunnette JH, Weinshilboum RM (1982) Pharmacogenetics of human thiopurine methyltransferase: kidney-erythrocyte correlation and immunolitration studies. J Pharmacol Exp Ther 222: 174
    • (1982) J Pharmacol Exp Ther , vol.222 , pp. 174
    • Woodson, L.C.1    Dunnette, J.H.2    Weinshilboum, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.