Changing residue 338 in human factor IX from arginine to alanine causes an increase in catalytic activity

Journal of Biological Chemistry

Volumn 273, Issue 20, 1998, Pages 12089-12094

  Chang, Jinli ^a   Jin, Jianping ^a   Lollar, Pete ^b   Bode, Wolfram ^c   Brandstetter, Hans ^c   Hamaguchi, Nobuko ^a   Straight, David L ^a   Stafford, Darrel W ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANILIDE; ARGININE; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9A; HEPARIN; METHYLSULFONYLCYCLOHEXYLGLYCYLARGININE 4 NITROANILIDE; MUTANT PROTEIN; RECOMBINANT PROTEIN; THROMBIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; KINETICS; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

FELIS CATUS;

EID: 0032524615     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.20.12089     Document Type: Article

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