Inactivation of leukocytes in platelet concentrates by photochemical treatment with psoralen plus UVA

Blood

Volumn 91, Issue 6, 1998, Pages 2180-2188

  Grass, Joshua A ^a   Hei, Derek J ^a   Metchette, Ken ^a   Cimino, George D ^a   Wiesehahn, Gary P ^a   Corash, Laurence ^a   Lin, Lily ^a  

^a CERUS CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4' AMINOMETHYL 4,5',8 TRIMETHYLPSORALEN; AROTINOLOL; INTERLEUKIN 8; METHOXSALEN; PSORALEN; THROMBOCYTE CONCENTRATE;

ARTICLE; CONTAMINATION; CONTROLLED STUDY; DNA SEQUENCE; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN CELL; PHOTOCHEMOTHERAPY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE TRANSFUSION; ULTRAVIOLET A RADIATION;

EID: 0032520987     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.6.2180     Document Type: Article

References (44)

1. Anderson KC, Weinstein HJ: Transfusion-associated graft-versus-host disease. N Engl J Med 323:315, 1990
2. Hathway WE, Fulginiti VA, Pierce CW, Githens JH, Pearlman DS, Muschenheim F, Kempe CH: Graft-vs-host reaction following a single blood transfusion. JAMA 201:139, 1967
3. Greenbaum B: Transfusion-associated graft-versus-host disease: Historical perspectives, incidence, and current use of irradiated blood products. J Clin Oncol 9:1889, 1991
4. Capon SM, DePond WD, Tyan DB, Pepkowtz SH, Toyoda H, Cinman AC, Azer PC, Goldfinger D: Transfusion-associated graft-versus-host disease in an immunocompetent patient. Ann Intern Med 114:1025, 1991
5. Benson K, Marks AR, Marshall MJ, Goldstein JD: Fatal graft-versus-host disease associated with transfusions of HLA-matched, HLA-homozygous platelets from unrelated donors. Transfusion 4:432, 1994
6. Takahashi K, Juji T, Kiyazaki H: Post-transfusion graft-versus-host disease occurring in non-immunosuppressed patients in Japan. Transfus Sci 12:281, 1991
7. Petz LD, Calhoun L, Yam P, Cecka M, Schiller G, Faithowicz AR, Herron R, Sayah D, Wallace RB, Belldegrun A: Transfusion-associated graft-versus-host disease in immunocompetent patients: Report of a fatal case associated with transfusion of blood from a second-degree relative, and survey of predisposing factors. Transfusion 33:742, 1993
8. Kernan NA, Collins NH, Juliano L, Cartagena T, Dupont B, O'reilly RJ: Clonable T lymphocytes in T-cell-depleted bone marrow transplants correlate with development of graft-v-host disease. Blood 68:770, 1986
9. Vallera D, Solderling C, Carlson G, Kersey J: Bone marrow transplantation across major histocompatibility barriers in mice. Transplantation 31:218, 1981
10. Spitzer TR: Transfusion induced graft-vs-bone disease, in Burakoff SJ, Deeg HJ, Ferrara J, Atkinson K (eds): Graft-vs.-Host Disease-Immunology, Pathophysiology and Treatment. NY, Marcel Dekker, 1990, p 539
11. Anderson KC: Clinical indications for blood component irradiation, in Baldwin ML, Jefferies LC (eds): Irradiation of Blood Components. Bethesda, MD, American Association of Blood Banks, 1992, p 31
12. Anderson KC, Goodnough LT, Sayers M, Pisciotto PT, Kurtz SR, Lane TA, Anderson CS, Silberstein LE: Variation in blood component irradiation practice: Implications for prevention of transfusion-associated graft-versus-host disease. Blood 77:2096, 1991
13. Pelzynski MM, Moroff G, Luban NLC, Taylor BJ, Quinones RR: Effect of gamma irradiation on T-cell inactivation as assessed by limiting dilution analysis: Implications for preventing transfusion associated graft vs. host disease. Blood 83:1683, 1994
14. Dodd RY: Adverse consequences of blood transfusion: Quantitative risk estimates, in Nance SJ (ed): Blood Supply: Risks, Perceptions and Prospects for the Future. Bethesda, MD, American Association of Blood Banks, 1994, p 1
15. Lin L, Cook DN, Wiesehahn GP, Alfonso R, Behrman B, Cimino GD, Corten L, Damonte PB, Dikeman R, Dupuis K, Fang YM, Hanson CV, Hearst JE, Lin CY, Londe HF, Metchette K, Nerio AT, Pu JT, Reames AA, Rheinschmidt M, Tessman J, Isaacs ST, Wollowitz S, Corash L: Photochemical inactivation of viruses and bacteria in human platelet concentrates using a novel psoralen and long wavelength ultraviolet light. Transfusion 37:423, 1997
16. Lin L, Wiesehahn GP, Morel PA, Corash L: Use of 8-methoxypsoralen and long wavelength ultraviolet radiation for decontamination of platelet concentrates. Blood 74:517, 1989
17. Lin L, Londe H, Janda JM, Hanson CV, Corash L: Photochemical inactivation of pathogenic bacteria in human platelet concentrates. Blood 83:2698, 1994
18. Cimino G, Gamper H, Isaacs S, Hearst J: Psoralens as photoactive probes of nucleic acid structure and function: Organic chemistry, photochemistry, and biochemistry. Ann Rev Biochem 54:1151, 1985
19. Wollowitz S, Fang Y, Pu JT, Nerio A, Spielmann HP, Lin L, Behrman B, Londe H, Alfonso R, Corash L, Isaacs S: Novel psoralens with enhanced UVA dependent inactivation of human immunodeficiency virus and reduced mutagenicity in the absence of UVA light. Blood 82(S1):402a, 1993 (abstr)
20. Alfonso R, Londe H, Cook D, Hanson CV, Rheinschmidt M, Behrman B, Lin L: Inactivation of cell free, cell associated, and proviral HIV-1 by the novel psoralen S-59 in human platelet concentrates. Blood 84(S1):530a, 1994 (abstr)
21. Corash L, Cook D, Reames A, Arnstein P: Photochemical decontamination of platelet concentrates prevents transfusion induced cytomegalovirus infection. Blood 84(S1):503a, 1994 (abstr)
22. Cook D, Lin C, Reames A, Marion PL: Inactivation of duck hepatitis B virus in human platelet concentrate by the novel psoralen S-59 and light. Transfusion 34(S):43S. 1994 (abstr)
23. Lin L, Behrman B, Rheinschmidt M, Mayaudon V, Payrat JM, Corash L: Evaluation of in vitro platelet function in synthetic media following photochemical decontamination treatment of apheresis platelet concentrates. Transfusion 34(S):71S, 1994 (abstr)
24. Wollowittz S, Isaacs ST, Rapoport H, Spielman HP, inventors; Cerus Corporation, assignee. Compounds for the photodecontamination of pathogens in blood. US Patent 5,399.719. 1995, March 21
25. Gulliksson H, Eriksson L, Hogman CF, Payrat JM: Buffy coat derived platelet concentrates prepared from half-strength citrate CPD and CPD whole blood units: Comparison between three additive solutions, in vitro studies. Vox Sang 68:152, 1995
26. Taswell C: Limiting dilution assays for the determination of immunocompetent cell frequencies: I data analysis. J Immunol 126: 1614, 1981
27. Kao KJ, Scornik JC: Accurate quantitation of the low number of white cells in white cell-depleted blood components. Transfusion 29:774, 1989
28. Gyllensten UB, Erlich HA: Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQα locus. Proc Natl Acad Sci USA 85:7652, 1988
29. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA: Primer directed enzyme amplification of DNA with thermostable DNA polymerase. Science 239:487, 1987
30. Lowenthal RM, Challis DR, Griffiths AE, Chappell RA, Goulder PJR: Transfusion-associated graft-versus-host disease: Report of an occurrence following the administration of irradiated blood. Transfusion 33:524, 1993
31. Stack G, Snyder EL: Cytokine generation in stored platelet concentrates. Transfusion 34:20, 1994
32. Heddle NM, Klama L, Singer J, Richards C, Fedak P, Walker I, Kelton JG: The role of the plasma from platelet concentrates in transfusion reactions. N Engl J Med 331:625, 1995
33. Stack G, Baril L, Napychank P, Snyder E: Cytokine generation in stored, white cell-reduced, and bacterially contaminated units of red cells. Transfusion 35:199, 1995
34. Muylle L, Peetermans ME: Effect of prestorage leukocyte removal on the cytokine levels in stored platelet concentrates. Vox Sang 66:14, 1994
35. Hei DJ, Grass J, Lin L, Cimino GD: Inhibition of cytokine synthesis in pooled platelet concentrates by treatment with psoralen plus UVA. 23rd Annual Meeting of the American Society of Photobiology and Photochemistry. 61:13(S), 1995 (abstr)
36. Neuner P, Charvat B, Knobler R, Kirnbauer R, Schwarz A, Luger TA, Schwarz T: Cytokine release by peripheral blood mononuclear cells is affected by 8-methoxypsoralen plus UV-A. Photochem Photobiol 59:182, 1994
37. Stack G, Baril L, Napychank P, Snyder EL: Cytokine generation in stored, white cell-reduced, and bacterially contaminated units of red cells. Transfusion 35:199, 1995
38. Setlow RB, Setlow JK: Effect of radiation on polynucleotides, in Baldwin ML, Jeffries LC (eds): Irradiation of Blood Components. Bethesda, MD, American Association of Blood Banks, 1992, p 1
39. Lin L, Londe H, Hanson C, Wiesehahn G, Isaacs S, Cimino G, Corash L: Photochemical inactivation of cell associated human immunodeficiency virus in platelet concentrate. Blood 82:292, 1993
40. Claas FHJ, Smeenk RJT, Schmidt R, Van Steenbrugge GJ, Eernisse JG: Alloimmunization against MHC antigens after platelet transfusion is due to contaminating leukocytes in the platelet suspension. Exp Hematol 9:84, 1981
41. Grana NH, Kao KJ : Use of 8-Methoxypsoralen and ultraviolet-A pretreated platelet concentrates to prevent alloimmunization against class I major histocompatability antigens. Blood 77:2530, 1991
42. 1 hybrid recipients: Implications for transfusion-associated graft-versus-host disease. Blood 86:3090, 1995
43. Ullrich SE: Photoinactivation of T-cell function with psoralen and UVA radiation suppresses the induction of experimental murine graft-versus-host disease across major histocompatibility barriers. J Invest Dermatol 96:303, 1991
44. Grass J, Wafa T, Reames A, Wages D, Ferrara J, Lin L, Corash L: Prevention of transfusion-associated graft versus host disease (TA-GVHD) by photochemical treatment (PCT). Blood 88(S1):627a, 1996 (abstr)