Differential regulation of IL-4 and IL-13 secretion by human basophils: Their relationship to histamine release in mixed leukocyte cultures

Journal of Immunology

Volumn 160, Issue 4, 1998, Pages 1957-1964

  Redrup, Angela C ^b   Howard, Brian P ^b   MacGlashan Jr , Donald W ^b   Kagey Sobotka, Anne ^b   Lichtenstein, Lawrence M ^b   Schroeder, John T ^a,b  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISINDOLYLMALEIMIDE; HISTAMINE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 13; INTERLEUKIN 3; INTERLEUKIN 4; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C INHIBITOR; TACROLIMUS;

ALLERGY; ARTICLE; BASOPHIL; CONTROLLED STUDY; GENE EXPRESSION; HISTAMINE RELEASE; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; LEUKOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANTIBODIES, ANTI-IDIOTYPIC; BASOPHILS; CELL SEPARATION; CELLS, CULTURED; HISTAMINE RELEASE; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-13; INTERLEUKIN-4; LYMPHOCYTE CULTURE TEST, MIXED; TACROLIMUS;

EID: 0032519678     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Charlesworth, E. N., A. F. Hood, N. A. Soter, A. Kagey-Sobotka, P. S. Norman, and L. M. Lichtenstein. 1989. Cutaneous late-phase response to allergen. Mediator release and inflammatory cell infiltration. J. Clin. Invest. 83:1519.
2. Iliopoulous, O., F. Baroody, R. M. Naclerio, B. S. Bochner, A. Kagey-Sobotka, and L. M. Lichtenstein. 1992. Histamine containing cells obtained from the nose hours after antigen challenge have functional and phenotypic characteristics of basophils. J. Immunol. 148:2223.
3. Guo, C.-B., M. C. Liu, S. J. Galli, B. S. Bochner, A. Kagey-Sobotka, and L. M. Lichtenstein. 1993. Identification of IgE-bearing cells in the late phase response to antigen in the lung as basophils. Am. J. Resp. Cell. Mol. Biol. 10:384.
4. Koshino, T., S. Teshima, N. Fukushima, T. Takaishi, K. Hirai, Y. Miyamoto, Y. Arai, Y. Sano, K. Ito, and Y. Morita. 1993. Identification of basophils by immunohistochemistry in the airways of postmortem cases of fatal asthma. Clin. Exp. Allergy 23:919.
5. Schroeder, J. T., A. Kagey-Sobotka, and L. M. Lichtenstein. 1995. The role of the basophil in allergic inflammation. Allergy 50:463.
6. MacGlashan, D. W., Jr., J. M. White, S. K. Huang, S. J. Ono, J. Schroeder, and L. M. Lichtenstein. 1994. Secretion of interleukin-4 from human basophils: the relationship between IL-4 mRNA and protein in resting and stimulated basophils. J. Immunol. 152:3006.
7. Kasaian, M., M. Clay, M. Happ, R. Garman, S. Hirani, and M. Luqman. 1996. IL-4 production by allergen-stimulated primary cultures: identification of basophils as the major IL-4-producing cell type. Int. Immunol. 8:1287.
8. Ochensberger, B., G.-C. Daepp, S. Rihs, and C. Dahinden. 1996. Human blood basophils produce interleukin-13 in response to IgE-receptor-dependent and -independent activation. Blood 88:3028.
9. Li, H., T. Sim, and R. Alam. 1996. IL-13 released by and localized in human basophils. J. Immunol. 156:4833.
10. Gibbs, B., H. Haas, F. Falcone, C. Albrecht, I. Vollrath, T. Noll, H. Wolff, and U. Amon. 1996. Purified human peripheral blood basophils release interleukin-13 and preformed interleukin-4 following immunological activation. Eur. J. Immunol. 26:2493.
11. Li, H., T. Sim, J. Grant, and R. Alam. 1996. The production of macrophage inflammatory protein-α by human basophils. J. Immunol. 157:1207.
12. de Vries, J. E., and G. Zurawski. 1995. Immunoregulatory properties of IL-13: its potential role in atopic disease. Int. Arch. Allergy Immunol. 106:175.
13. Moser, R., and J. Fehr. 1992. IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J. Immunol. 149:1432.
14. Schleimer, R. P., S. A. Sterbinsky, J. Kaiser, C. A. Bickel, D. A. Klunk, K. Tomioka, W. Newman, F. W. Luscinskas, M. A. Gimbrone, and B. S. Bochner. 1992. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. J. Immunol. 148:1086.
15. Thornhill, M. A., U. Kyan-Aung, and D. O. Haskard. 1990. IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils. J. Immunol. 144:3060.
16. Bochner, B., D. Klunk, S. Sterbinsky, R. Coffman, and R. Schleimer. 1995. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J. Immunol. 154:799.
17. Swain, S., A. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796.
18. Abehsira-Amar, O., M. Gilbert, M. Jolly, J. Theze, and D. Jankovic. 1992. IL-4 plays a dominant role in the differential development of Th0 into Th1 and Th2 cells. J. Immunol. 148:3820.
19. + T helper type 2 cells. J. Exp. Med. 181:5.
20. Adkinson, N. F., Jr. 1980. Measurement of Total Serum Immunoglobulin E and Allergen-Specific Immunoglobulin E Antibody, 2nd ed.). American Society of Microbiology, Washington, D.C., p. 800.
21. Schroeder, J. T., D. W. MacGlashan, Jr., A. Kagey-Sobotka, J. M. White, and L. M. Lichtenstein. 1994. IgE-dependent IL-4 secretion by human basophils: the relationship between cytokine production and histamine release in mixed leukocyte cultures. J. Immunol. 153:1808.
22. Gilbert, H. S., and L. Ornstein. 1975. Basophil counting with a new staining method using alcian blue. Blood 46:279.
23. Schroeder, J., L. Lichtenstein, and S. MacDonald. 1996. An IgE-dependent recombinant histamine-releasing factor induces IL-4 secretion from human basophils. J. Exp. Med. 183:1265.
24. Schroeder, J. T., D. W. MacGlashan, Jr., S. M. MacDonald, A. Kagey-Sobotka, and L. M. Lichtenstein. 1997. Regulation of IgE-dependent IL-4 generation by human basophils treated with glucocorticoids. J. Immunol. 158:5448.
25. Schroeder, J. T., L. M. Lichtenstein, and S. M. MacDonald. 1997. Recombinant histamine releasing factor enhances immunoglobulin E-dependent interleukin-4 and -13 secretion by human basophils. J. Immunol. 159:447.
26. Siraganian, R. P. 1974. An automated continuous-flow system for the extraction and fluorometric analysis of histamine. Anal. Biochem. 57:383.
27. Schroeder, J. T., L. M. Lichtenstein, A. Kagey-Sobotka, and D. W. MacGlashan, Jr. 1995. Differential control of basophil histamine and IL-4 secretion with PKC activation. J. Allergy Clin. Immunol. 95:A344.
28. Toullec, D., P. Pianetti, H. Coste, P. Bellevergue, P. T. Grand, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, F. Loriolle, L. Duhamel, D. Charon, and J. Kirilovsky. 1991. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266:15771.
29. Ochensberger, B., S. Rihs, T. Brunner, and C. Dahinden. 1995. IgE-independent interleukin-4 expression and induction of a late phase of leukotriene C4 formation in human blood basophils. Blood 86:4039.
30. Zurawski, S. M., P. Chomarat, O. Djossou, C. Bidaud, A. N. McKenzie, P. Miossec, J. Banchereau, and G. Zurawski. 1995. The primary binding subunit of the human interleukin receptor is also a component of the interleukin-13 receptor. J. Biol. Chem. 270:13869.
31. Punnonen, J., G. Aversa, B. Cocks, A. McKenzie, S. Menon, G. Zurawski, R. de Waal Malefyt, and J. de Vries. 1993. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. USA 90:3730.
32. Defrance, T., P. Carayon, G. Billian, J.-C. Guillemot, M. A., D. Caput, and P. Ferrara. 1994. Interleukin 13 is a B cell stimulating factor. J. Exp. Med. 179:135.
33. Gauchat, J.-F., S. Henchoz, G. Mazzel, J.-P. Aubry, T. Brunner, H. Blasey, P. Life, D. Talabot, L. Flores-Romo, J. Thompson, K. Kishl, J. Butterfield, C. Dahinden, and J.-Y. Bonnefoy. 1993. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 365:340.
34. Dvorak, H. F., A. M. Dvorak, B. A. Simpson, H. B. Richerson, S. Leskowitz, and M. J. Karnovsky. 1970. Cutaneous basophil hypersensitivity. II. A light and electron microscopic description. J. Exp. Med. 132:558.
35. Dvorak, H. F., and M. C. Mihm, Jr. 1972. Basophilic leukocytes in allergic contact dermatitis. J. Exp. Med. 135:235.
36. Dvorak, A. M., and R. A. Monahan. 1982. Crohn's disease. Ultrastructural studies showing basophil leukocyte granule changes and lymphocyte parallel tubular arrays in peripheral blood. Arch. Pathol. Lab. Med. 106:145.
37. Casolaro, V., S. Georas, Z. Song, I. Zubkoff, S. Abdulkadir, D. Thanos, and S. Ono. 1995. Inhibition of NF-AT-dependent transcription by NF-κB: implications for differential gene expression in T helper cell subsets. Proc. Natl. Acad. Sci. USA 92:11623.
38. Paliogianni, F., N. Hama, G. Mavrothlassitis, G. Thyphhronitis, and D. Boumpas. 1996. Signal requirements for interleukin 4 promoter activation in human T cells. Cell. Immunol. 168:33.
39. Hutchinson, L., and M. McCloskey. 1995. Fc∈RI-mediated induction of nuclear factor of activated T-cells. J. Biol. Chem. 270:16333.
40. Azam, M., H. Erdjument-Bromage, B. Kreider, M. Xia, F. Quelle, R. Basu, C. Saris, P. Tempst, J. Ihle, and C. Schindler 1995. Interleukin-3 signals through multiple isoforms of STAT5. EMBO J. 14:1402.
41. Mui, L.-F., A. H. Wakao, A.-M. O'Farrell, N. Harada, and A. Miyajima. 1995. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J. 14:1166.
42. Rao, A. 1994. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 15:274.